Results 131 to 140 of about 902,310 (311)

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

open access: yesHepatology, EarlyView., 2022
Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim   +12 more
wiley   +1 more source

The prevalence of vertical transmission of human immunodeficiency virus and associated factors among exposed infants in Eastern Lake zone and Southern Highland of Tanzania: a cross-sectional study

open access: yesHIV Research & Clinical Practice
Background Globally, the rate of antiretroviral therapy coverage for pregnant women living with human immunodeficiency virus (HIV) increased by 38% between 2010 and 2015 but only by 2% between 2016 and 2020.
Peter Richard Torokaa   +20 more
doaj   +1 more source

Treatment of chronic hepatitis B: options, monitoring, special cases and adverse effects

open access: yesJournal of Education, Health and Sport
Introduction:  Hepatitis B remains a significant clinical issue. Despite the availability of effective vaccines, the world is still not free from this problem.
Mateusz Litwin Litwin   +8 more
doaj   +1 more source

Missing Women: Some Recent Controversies on Levels and Trends in Gender Bias in Mortality [PDF]

open access: yes
This paper discusses two recent controversies surrounding levels and trends in the number of ‘missing women’ in the world. First, the impact of fertility decline on gender bias in mortality is examined.
Stephan Klasen
core  

The National Clinical Database Risk Calculator and the 5‐Item Modified Frailty Index Predict the Development of Postoperative Delirium After Surgery for Hepatocellular Carcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study demonstrates that combining the NCD Risk Calculator with the mFI‐5 enables more precise stratification of postoperative delirium risk in patients undergoing surgery for HCC. Patients classified as high risk by the combined model showed a markedly higher incidence of delirium than those in the intermediate‐ and low‐risk groups.
Kiyotaka Hosoda   +9 more
wiley   +1 more source

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

open access: yesHepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai   +29 more
wiley   +1 more source

Multifactor Risk Stratification for Post‐Transplant Alcohol Relapse Using Abstinence, Psychosocial, and Socioeconomic Factors

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Alcohol relapse after liver transplantation is difficult to predict using abstinence duration alone. We developed a multifactor model integrating abstinence duration, psychosocial risk (SIPAT), and socioeconomic context (AUC 0.70). This approach may support individualized risk assessment and tailored follow‐up intensity; external validation is needed ...
Ayato Obana   +9 more
wiley   +1 more source

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

open access: yesHepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo   +14 more
wiley   +1 more source

Viral hepatitis B and C among immigrants in Iceland [PDF]

open access: yes, 2006
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/OpenBACKGROUND: Viral hepatitis B and C are a major health problem worldwide. The prevalence of these diseases varies throughout the world.
Gestur Pálsson   +5 more
core  

Efficacy and Safety of a Simple Auxiliary Liver Suspension Device in Complex Laparoscopic Hepatectomy: A Multicenter Randomized Clinical Trial

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Purpose To evaluate the efficacy and safety of a novel auxiliary liver suspension device in complex laparoscopic hepatectomy. Methods A total of 253 patients with hepatocellular carcinoma (HCC) undergoing complex laparoscopic hepatectomy at the Third Affiliated Hospital of Naval Medical University, Sichuan Provincial People's Hospital, and ...
Xiao‐Ying Zhu   +9 more
wiley   +1 more source

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