Results 111 to 120 of about 281,611 (124)
Progress in Aptamer Research and Future Applications
ChemistryOpen, EarlyView.This paper mainly describes the screening method of aptamer, the screening difficulties and improvement methods of small molecule aptamer, and the application and treatment of aptamer. It explores the latest progress and application of aptamers, and summarises them, thus indicating some problems that still exist in this field.
Song Liu +4 more
wiley +1 more source
Portal Hypertension &Cirrhosis, EarlyView.The advantages to measure handgrip strength (HGS) are simple, convenient, noninvasive, cost‐effective, and easy to be widely carried out during daily clinical practice. Mounting evidence demonstrates that muscle strength measured by HGS is a feasible and reliable metric to evaluate nutritional status, as well as relevant cirrhosis‐related complications
Binxin Cui, Ziyi Yang, Chao Sun
wiley +1 more source
Visualization and hotspot analysis of CAR‐T research based on CiteSpace
Precision Medical Sciences, EarlyView.Articles on CAR‐T cells were collected from the Web of Science Core Collection (WoSCC). Key bibliometric characteristics were analyzed using CiteSpace. Our findings showed that CAR‐T cell therapy is a cutting‐edge field that has drawn a lot of interest, that its depth and excitement for research are growing, and that it may face further challenges and ...
Kejin Li +6 more
wiley +1 more source
Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
Small, EarlyView.The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa +4 more
wiley +1 more source
Small Methods, EarlyView.This review explores the dual roles of exosomes in gastrointestinal (GI) cancers as diagnostic biomarkers and therapeutic agents. It highlights advancements in exosomal miRNAs, lncRNAs, circRNAs, and proteins for cancer detection and prognosis. The study also examines engineering strategies for exosome‐based drug delivery systems, their potential to ...
Mohit J. Mehta +7 more
wiley +1 more source
Small Structures, EarlyView.This illustration depicts a comprehensive strategy against monkeypox, showcasing its transmission, symptoms, and prevention. Centralized around nanomaterials and biosensors, it integrates early screening, Internet of Things, vaccination, and community involvement through collaboration among healthcare workers, scientists, researchers, social groups ...
Vishal Chaudhary +3 more
wiley +1 more source
Pediatric Autoimmune Pancreatitis: Clinical Findings and Outcomes in Sweden
United European Gastroenterology Journal, EarlyView.ABSTRACT Introduction Pediatric autoimmune pancreatitis (AIP) is a rare form of pancreatitis in children with poorly understood pathophysiology. It is a recognized risk factor for chronic pancreatitis in approximately 4% of pediatric cases. This study aims to describe the demographics, clinical characteristics, and outcomes of a large Swedish cohort of
Miroslav Vujasinovic +9 more
wiley +1 more source
FASEB BioAdvances, EarlyView.Furin interacted with PTEN‐L and activated PINK1/Parkin‐mediated mitophagy in HSCs. Furin inhibited HSC activation and alleviated liver fibrosis by regulating the PTEN‐L/PINK1/Parkin axis. Abstract Hepatic Stellate cells (HSCs) play an important role during liver fibrosis progression; more and more evidence indicates that mitophagy greatly regulates ...
Yan‐Wei Song +2 more
wiley +1 more source
A Guide to Screening for Autoimmune Diseases in Patients With Vulvar Lichen Sclerosus
Australasian Journal of Dermatology, EarlyView.ABSTRACTBackgroundThe aetiology of vulvar lichen sclerosus (VLS) remains unknown. However, there is evidence that in addition to a genetic predisposition, autoimmunity contributes to the pathogenesis.ObjectivesThe objective of this study was to determine the prevalence of autoimmune disease and positive autoantibody serology in patients with VLS ...
Annabel Guttentag +5 more
wiley +1 more source
Feedback regulation of VISTA and Treg by TNF‐α controls T cell responses in drug allergy
Allergy, EarlyView.TNF‐α breaks immune tolerance by regulating the VISTA at early stage of the drug‐specific T‐cell response. The response of drug‐responsive effector T cells was negative feedback regulated by increasing Treg cells. This indicates that Treg agonists, rather than TNF‐α antagonists, could be used to treat patients with progressive SCARs.
Lele Sun +14 more
wiley +1 more source