Non-responsiveness to hepatitis-B vaccination: revaccination and immunogenetic typing [PDF]
Krämer A, Herth D, von Keyserlingk H, et al. Non-responsiveness to hepatitis-B vaccination: revaccination and immunogenetic typing. Klinische Wochenschrift.
Sommer, D. +7 more
core +1 more source
Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection [PDF]
Deletion, anergy, and a spectrum of functional impairments can affect virus-specific CD8 cells in chronic viral infections. Here we characterize a low frequency population of CD8 cells present in chronic hepatitis B virus (HBV) infection which survive in
Ogg, GS +29 more
core +1 more source
German experimental hepatitis B vaccine: influence of variation of dosage schedule, sex and age differences on immunogenicity in health care workers [PDF]
Krämer A, Sommer D, Hahn EG, Riecken E-O. German experimental hepatitis B vaccine: influence of variation of dosage schedule, sex and age differences on immunogenicity in health care workers. Klinische Wochenschrift.
Sommer, D. +3 more
core +1 more source
Epidemiological patterns of hepatitis B virus (HBV) in highly endemic areas [PDF]
This paper uses meta-analysis of published data and a deterministic mathematical model of hepatitis B virus (HBV) transmission to describe the patterns of HBV infection in high endemicity areas.
Edmunds, W. John +5 more
core +1 more source
Viral adaptation to host immune responses occurs in chronic hepatitis B virus (HBV) infection, and adaptation is greatest in HBV e antigen-negative disease [PDF]
Hepatitis B virus (HBV)-specific T-cell responses are important in the natural history of HBV infection. The number of known HBV-specific T-cell epitopes is limited, and it is not clear whether viral evolution occurs in chronic HBV infection. We aimed to
Chopra, A. +56 more
core +1 more source
Background Although vaccines for hepatitis B virus (HBV) are highly effective, HBV infections in vaccinees occur. Index samples of breakthrough infections are typically anti-HBc negative but HBV DNA positive with protective anti-HBs levels while HBsAg ...
Mary C. Kuhns +3 more
doaj +1 more source
Changes in viral load and HBsAg and HBeAg status with age in HBV chronic carriers in The Gambia. [PDF]
BACKGROUND: Little is known about changes in hepatitis B viral load (HBV DNA) in relation to age in Africa. The aim of this study is to determine the natural course of HBV chronic infection, particularly in relation to sequential changes in serum HBV DNA
Jeffries, David +31 more
core +1 more source
Background Although several cases of hepatitis B virus reactivation have been described in patients with a history of hepatitis B virus infection while undergoing treatment for hepatitis C virus infection with direct acting antivirals, the question of ...
Luca Foroghi Biland +10 more
doaj +1 more source
Background: The ultimate goal of hepatitis B treatment is hepatitis B surface antigen (HBsAg) seroclearance. Several factors have been suggested to be associated with the rate of HBsAg reduction in antiviral-naive or lamivudine therapy cohorts.
Xia-Xia Zhang +6 more
doaj +1 more source
Can HBsAg Be Used as a Viral Replication Marker in Chronic Hepatitis B Patients?
Objective: Monitoring hepatitis B virus (HBV) treatment responses and virus replication is performed with molecular tests. However, these tests are either expensive or invasive. A new and more practical marker is needed.
Emel UZUNOĞLU +4 more
doaj +1 more source

