Results 41 to 50 of about 16,590,594 (260)

Maternal hepatitis B and infant infection among pregnant women living with HIV in South Africa

Journal of the International AIDS Society, 2014
Introduction Globally, hepatitis B virus (HBV) infection is the leading cause of liver‐related mortality. Newborn vaccination, maternal antiviral therapy and administering hepatitis B immune globulin shortly after birth can greatly reduce the risk of ...
Christopher J Hoffmann, Fildah Mashabela, Silvia Cohn, Jennifer D Hoffmann, Sanjay Lala, Neil A Martinson, Richard E Chaisson   +6 more
doaj   +1 more source

Avaliação da memória imunológica para o vírus da hepatite B em indivíduos vacinados [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências de Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2014A susceptibilidade à infecção pelo vírus da hepatite B (HBV) e necessidade de doses de reforço da vacina ...
Livramento, Andréa do
core  

Viral Hepatitis and Rapid Diagnostic Test Based Screening for HBsAg in HIV-infected Patients in Rural Tanzania. [PDF]

, 2013
\ud \ud Co-infection with hepatitis B virus (HBV) is highly prevalent in people living with HIV in Sub-Saharan Africa. Screening for HBV surface antigen (HBsAg) before initiation of combination antiretroviral therapy (cART) is recommended. However, it is
Emilio Letang, Mwaigomole, Geoffrey, Battegay, Manuel, Lars Henning, Abdul, Omary, Marcel Tanner, Hatz, Christoph, Ngwale, Ramadhani, Franzeck Fabian C., Henning, Lars, Geoffrey Mwaigomole, Ramadhani Ngwale, Marian Hamisi, Tanner, Marcel, Omary Abdul, Ngwale Ramadhani, Hamisi, Marian, Mwaigomole Geoffrey, Bernadeta Msongole, Henning Lars, Tanner Marcel, Franzeck, Fabian C., Manuel Battegay, Msongole Bernadeta, Fabian C Franzeck, Fabian C. Franzeck, Msongole, Bernadeta, Letang, Emilio, Hamisi Marian, Hatz Christoph, Letang Emilio, Battegay Manuel, Christoph Hatz, Franzeck, Fabian C, Abdul Omary   +34 more
core   +2 more sources

A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints

Advanced Science, EarlyView.
ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu, Jun Yang, Yuhang Zhang, Xiaoli Xue   +3 more
wiley   +1 more source

Seropositive for hepatitis B and C viruses is associated with the risk of decreased bone mineral density in adults: An analysis of studies from the NHANES database

Frontiers in Medicine, 2023
BackgroundSome studies had reported that patients with viral hepatitis are at increased risk of reduced bone mineral density and even osteoporosis.
Jiasheng Tao, Zijian Yan, Wenmian Huang, Tao Feng   +3 more
doaj   +1 more source

52-week efficacy and safety of telbivudine with conditional tenofovir intensification at week 24 in HBeAg-positive chronic Hepatitis B [PDF]

, 2013
Background and Aims: The Roadmap concept is a therapeutic framework in chronic hepatitis B for the intensification of nucleoside analogue monotherapy based on early virologic response.
Tawesak Tanwandee (279135), Jorge Daruich, Wattana Sukeepaisarnjaroen, Rashidkhan Pathan, Eduardo Fassio, Fernando Bessone (254729), Suzane K Ono, Daruich, Jorge, Pessôa, Mário Guimarães, Yuhong Dong, Tanwandee, Tawesak, Rashidkhan Pathan (279143), Sukeepaisarnjaroen, Wattana, Mário G Pessôa, Ono, Suzane K., Teerha Piratvisuth (279131), Piyawat Komolmit (279133), Chan, Henry L. Y., Henry L Y Chan, Dong, Yuhong, Piratvisuth, Teerha, Pessôa, Mário G., Mário G. Pessôa (279138), Stefan Zeuzem (22856), Hugo Cheinquer (279142), Stefan Zeuzem, Trylesinski, Aldo, Pathan, Rashidkhan, Bessone, Fernando, Suzane K. Ono (279140), Henry L. Y. Chan (279137), Aldo Trylesinski (279145), Fassio, Eduardo, Piyawat Komolmit, Henry L. Y. Chan, Ono, Suzane Kioko, Komolmit, Piyawat, Jorge Daruich (279141), Hugo Cheinquer, Eduardo Fassio (279139), Cheinquer, Hugo, Chan, Henry, Tawesak Tanwandee, Mário G. Pessôa, Aldo Trylesinski, Suzane K. Ono, Teerha Piratvisuth, Fernando Bessone, Wattana Sukeepaisarnjaroen (279136), Yuhong Dong (279144), Zeuzem, Stefan   +50 more
core   +2 more sources

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Evolution of hepatitis B serological markers in HIV coinfected patients: a case study

Revista de Saúde Pública
OBJECTIVE To describe the evolution of serological markers among HIV and hepatitis B coinfected patients, with emphasis on evaluating the reactivation or seroreversion of these markers. METHODS The study population consisted of patients met in an AIDS
Ana Luiza de Castro Conde Toscano, Maria Cássia Mendes Corrêa   +1 more
doaj   +1 more source

Kinetics of Hepatitis B Surface Antigen Level in Chronic Hepatitis B Patients who Achieved Hepatitis B Surface Antigen Loss during Pegylated Interferon Alpha-2a Treatment

Chinese Medical Journal, 2017
Background: Hepatitis B surface antigen (HBsAg) loss/seroconversion is considered to be the ideal endpoint of antiviral therapy and the ultimate treatment goal in chronic hepatitis B (CHB). This study aimed to assess the patterns of HBsAg kinetics in CHB
Ming-Hui Li, Lu Zhang, Xiao-Jing Qu, Yao Lu, Ge Shen, Shu-Ling Wu, Min Chang, Ru-Yu Liu, Lei-Ping Hu, Zhen-Zhen Li, Wen-Hao Hua, Shu-Jing Song, Yao Xie   +12 more
doaj   +1 more source

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

Advanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun, Junhao Fan, Xiaolu Xie, Yuting Shi, Xiaoqing Liu, Tiefeng Xu, Sidi Yang, Keda Shi, Chengshu Xie, Shixiong Li, Siwen Chen, Ruoxi Cai, Ping He, Yuzhen Ye, Tao Chen, Xiancai Ma, Chunmei Li, Jingyou Yu, Deyin Guo   +18 more
wiley   +1 more source