Results 71 to 80 of about 16,590,594 (260)

The Role of New Viral Biomarkers in Chronic Hepatitis B: Ready to Use in the Clinical Practice?

open access: yesViral Hepatitis Journal, 2018
Recent advances have been made to develop and improve the serologic and molecular virologic tools for the diagnosis and optimal management of chronic hepatitis B (CHB) infection.
Suna YAPALI
doaj   +1 more source

Hepatitis B virus infection and associated factors among pregnant women attending antenatal clinics in West Hararghe public hospitals, Oromia region, Ethiopia

open access: yesThe Pan African Medical Journal, 2020
INTRODUCTION: Globally, approximately 350-400 million persons are chronically infected with hepatitis B virus (HBV), over 65 million of whom are in Africa. One in four people with chronic hepatitis B develop serious health problems.
Belay Mamuye   +2 more
doaj   +1 more source

Preoperative FIB‐4 Index as a Potential Factor Associated With Severe Postoperative Complications and Endogenous Organ Failure After Hepatectomy for Hepatocellular Carcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study demonstrates that a preoperative FIB‐4 index ≥ 5.0 independently predicts severe complications and endogenous organ failure (EOF) following hepatectomy for hepatocellular carcinoma. By capturing structural liver fragility and systemic vulnerability, the FIB‐4 index enhances surgical risk stratification beyond traditional functional markers ...
Masanori Nakamura   +9 more
wiley   +1 more source

A Multivalent mRNA Therapeutic Vaccine Exhibits Breakthroughs in Immune Tolerance and Virological Suppression of HBV by Stably Presenting the Pre-S Antigen on the Cell Membrane

open access: yesPharmaceutics
Background/Objectives: In chronic hepatitis B infection (CHB), the hepatitis B surface antigen (HBsAg) continuously exhausts the hepatitis B surface antibody (HBsAb), which leads to the formation of immune tolerance.
Shang Liu   +10 more
doaj   +1 more source

A new group of hepadnaviruses naturally infecting Orangutans (Pongo pygmaeus) [PDF]

open access: yes, 1999
A high prevalence (42.6%) of hepatitis B virus (HBV) infection was suspected in 195 formerly captive orangutans due to a large number of serum samples which cross-reacted with human HBV antigens.
Heeney, J.L.   +4 more
core  

Mac‐2 Binding Protein Glycosylation Isomer (M2BPGi)–Based Risk Stratification Refined by Tumor Metabolic Activity in Hepatocellular Carcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
M2BPGi reflects background liver fibrosis and hepatic functional impairment. PET SUVmax reflects tumor metabolic aggressiveness. Their combination identifies a dual‐high subgroup with the poorest recurrence‐free and overall survival. ABSTRACT Aim To evaluate the prognostic significance of preoperative Mac‐2 binding protein glycosylation isomer (M2BPGi)
Kojiro Shirabe   +8 more
wiley   +1 more source

Occult hepatitis B virus infection and its demographic and clinical determinants among blood donors in Saudi Arabia: A retrospective cross-sectional study

open access: yesJournal of International Medical Research
Objective Occult hepatitis B virus infection, characterized by the presence of hepatitis B virus DNA in the absence of detectable hepatitis B surface antigen, poses a significant risk to blood donation safety. This study aimed to determine the prevalence
Abdulrahman F Alrezaihi   +5 more
doaj   +1 more source

Erratum to 'The management of chronic hepatitis B in the immunocompromised patient: recommendations from a single topic meeting' [J. Clin. Virol. 41 (4) 2008 243-254] [PDF]

open access: yes, 2008
Patients with chronic hepatitis B virus (HBV) infection have a substantial risk of reactivation and jaundice following the use of immunosuppressant therapy.
Pol, Stanislas   +7 more
core  

Expression of hepatitis B small surface antigen in Santalum album embryogenic cell suspension cultures

open access: yes, 2010
Embryogenic cell suspension cultures of Santalum album were transformed with Agrobacterium tumefaciens harboring pD35SHER plant expression vector having hepatitis B small surface antigen (HBsAg) with a C-terminal ER retention signal.
U. K. S. Shekhawat   +2 more
core   +1 more source

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