Results 81 to 90 of about 16,590,594 (260)

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

open access: yesAnimal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang   +10 more
wiley   +1 more source

Association of Cytokines with Alanine Aminotransferase, Hepatitis B Virus Surface Antigen and Hepatitis B Envelope Antigen Levels in Chronic Hepatitis B

open access: yesChinese Medical Journal, 2018
Background: Cytokines play an important role in occurrence and recovery of hepatitis B virus (HBV) infection. The aim of this study was to investigate the changes of cytokines concentration and its correlation to alanine aminotransferase (ALT), HBV ...
Ming-Hui Li   +18 more
doaj   +1 more source

A rational approach to the development of future generation processes for lipoprotein VLP vaccine candidates [PDF]

open access: yes, 2009
Lipoprotein VLPs, known also as lipid-envelope VLPs, are expressed intracellularly in yeast, localised on the host endoplasmic reticulum (ER). The main challenge in production lies in the complexity of the recovery and purification process.
Kee, G.K.
core  

Successful treatment of chronic hepatitis B and D with pegylated-interferon plus entecavir

open access: yes, 2017
Interferon-based regimen has been used to treat hepatitis D virus (HDV) super-infection on top of hepatitis B virus (HBV) carriers; however, viral relapse is frequent after stopping therapy. Recently, quantitative hepatitis B surface antigen (qHBsAg) was
Chen, Guei-Ying;Su, Tung-Hung;Kao, Jia-Horng   +1 more
core   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel   +12 more
wiley   +1 more source

SEROPREVALENCE OF HEPATITIS B AND C IN YOUNG ADULTS SEEKING RECRUITMENT IN ARMED FORCES

open access: yesPakistan Armed Forces Medical Journal, 2006
Background: Hepatitis B virus (HBV) and hepatitis C virus (HCV) are the commonest causes of chronic liver disease all over the world including Pakistan.
Irfan Ali Mirza   +5 more
doaj   +2 more sources

Rheumatology Informatics System for Effectiveness Registry Participation Associated With Significant Gains in Quality Measure Performance: An Interrupted Time Series Analysis

open access: yesArthritis &Rheumatology, EarlyView.
Objective To examine the association between participation in a qualified clinical data registry and quality measure performance. Methods We included practices that joined the American College of Rheumatology's Rheumatology Informatics System for Effectiveness (RISE) registry between 2015 and 2021.
Gabriela Schmajuk   +5 more
wiley   +1 more source

Management of Hepatitis B Surface Antigen and Hepatitis C Antibody-Positive Patients by Departments Not Specializing in Hepatology at a Suburban University Hospital in Japan: A Single-Center Observational Study [Corrigendum]

open access: yesInternational Journal of General Medicine, 2021
Tokushima Y, Tago M, Tokushima M, et al. Int J Gen Med. 2020;13:743—750. The authors have advised there are errors in Table 1 on page 746 in the Hbs-Ag positive patients’ data. The errors were introduced during the creation of ...
Tokushima Y   +6 more
doaj  

Stimulation requirement and pathogenetic significance of T cells during chronic viral hepatitis. [PDF]

open access: yes, 2007
Hepatitis B virus (HBV) and Hepatitis C virus (HCV) are important causes of liver inflammation and fibrosis. More than 500 million people are persistently infected worldwide and consequently are at increased risk of developing chronic liver disease ...
Kennedy, P.
core  

Purification of Disassembled Capsid Protein by Hydroxyapatite Chromatography Enhances Virus‐Like Particle Recovery

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Virus‐like particles (VLPs) are a promising modality with extensive applications in prophylactic and therapeutic vaccine design. Human Papillomavirus (HPV) vaccines are one such example where VLP vaccine applications have led to the successful reduction in HPV‐associated diseases, such as cervical cancer.
Nicholas Samuelson   +5 more
wiley   +1 more source

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