Results 171 to 180 of about 55,714 (316)

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Prevalence of rheumatoid factor in asymptomatic chronic hepatitis B surface carriers in the context of endemic malaria: cross-sectional study at University Hospital of Cocody, Abidjan, Côte d'Ivoire. [PDF]

Pan Afr Med J
Goran-Kouacou APV, Yéboah OR, Assi AUA, Séri YJ, Adou AH, N Guessan K, Dassé SR.   +6 more
europepmc   +1 more source

Intestinal permeability and immune‐inflammatory markers in patients with idiosyncratic drug‐induced liver injury, drug‐induced steatosis and metabolic dysfunction–associated steatotic liver disease (MASLD)

British Journal of Pharmacology, EarlyView.
Background and Purpose Adverse immuno‐inflammatory responses possibly influenced by bacterial compounds reaching the liver as a consequence of altered intestinal permeability appear to be crucial in the pathogenesis of drug‐induced liver injury and steatotic liver diseases.
Daniel E. Di Zeo‐Sánchez, Irene Díaz‐Alberola, José María Pinazo‐Bandera, Miren García‐Cortés, Judith Sanabria‐Cabrera, Mercedes Robles‐Díaz, Ismael Álvarez‐Álvarez, M. Isabel Lucena, Raúl J. Andrade, Marina Villanueva‐Paz, Camilla Stephens   +10 more
wiley   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

In Vitro Anti-Hepatitis B Virus Activity of Hydroxytyrosol from <i>Lindernia ruellioides</i>. [PDF]

Molecules
Zhao TS, Li KZ, Su HL, Liang B, Liang CQ, Gao JT, Zhou XL.   +6 more
europepmc   +1 more source

Long-term delta superinfection in hepatitis B surface antigen carriers and its relationship to the course of chronic hepatitis

, 1983
Massimo Colombo, Rita Cambieri, Maria Grazia Rumi, Guido Ronchi, E. Del Ninno, Roberto de Franchis   +5 more
openalex   +1 more source

SHBs Mitigates Sorafenib‐Induced Apoptosis in Hepatocellular Carcinoma via Activation of RAF1/MEK/ERK Signaling Pathway

Cancer Science, EarlyView.
Hepatitis B virus (HBV) infection is a major driver of hepatocellular carcinoma (HCC) and is associated with resistance to sorafenib, the first‐line treatment for advanced HCC. This study demonstrates that the small HBV surface antigen (SHBs) promotes sorafenib resistance by activating the RAF1/MEK/ERK signaling pathway, inhibiting apoptosis in HCC ...
Shuxiang Wu, Yuxiang Hong, Hang Li, Mengxian Lin, Xiaohuang Lin, Xinjian Lin, Xu Lin   +6 more
wiley   +1 more source

Hepatitis B virus infection after immunization: How serious it is? An updated review. [PDF]

Clin Exp Med
Marjani A, Alavian SM, Nassiri Toosi M, Alavian SH, Abazari MF, Khamseh A, Jazayeri SM.   +6 more
europepmc   +1 more source

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Hepatitis B virus genotype distribution and mutation patterns: Insights and clinical implications for hepatitis B virus positive patients. [PDF]

World J Exp Med
Ratnaparkhi MM, Vyawahare CR, Gandham NR.   +2 more
europepmc   +1 more source