Results 181 to 190 of about 55,714 (316)

NSun2‐Mediated tsRNAs Alleviate Liver Fibrosis via FAK Dephosphorylation

open access: yesCell Proliferation, EarlyView.
NSun2 deficiency inhibited sinusoidal capillarization, alleviating liver fibrosis. Reduced NSun2 expression led to alterations in the functional tsRNAs tRF‐1‐S25 and tRF‐5‐V31, which regulate sinusoidal capillarization by targeting key proteins, including DUSP1 and FAK – crucial clinical targets – offering a novel RNA‐based therapeutic approach for ...
Pengcheng Li   +14 more
wiley   +1 more source

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

open access: yesCell Proliferation, EarlyView.
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far   +4 more
wiley   +1 more source

Fermentation of recombinant yeast producing hepatitis B surface antigen [PDF]

open access: bronze, 1987
C. E. Carty   +3 more
openalex   +1 more source

Vaccination in Multiple Myeloma: Challenges and Strategies

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background Multiple myeloma (MM) is a hematological malignancy characterized by profound immunosuppression resulting from both disease‐related mechanisms and treatment‐induced immune dysfunction. This compromised immune status markedly increases susceptibility to infections, a leading cause of morbidity and mortality in MM patients.
Enrica Antonia Martino   +10 more
wiley   +1 more source

Age‐Specific Prevalence of Hepatitis B e Antigen (HBeAg) and Antibody to HBeAg (Anti‐HBe) among Asymptomatic Hepatitis B Surface Antigen (HBsAg) Carriers in Okinawa and Kyushu, Japan [PDF]

open access: bronze, 1986
Seizaburo Kashiwagi   +7 more
openalex   +1 more source

Acute hepatitis and haemolysis associated with doxycycline and rifampin administration in two weanling foals

open access: yesEquine Veterinary Education, EarlyView.
Summary Two foals were being treated with a combination of oral doxycycline and rifampin for presumed Rhodococcus equi infections. After 3–4 weeks of antimicrobial administration, both foals presented with icterus and nonspecific clinical signs, including lethargy and inappetence.
A. Murdock   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy