Results 181 to 190 of about 475,040 (341)

Hepatitis B virus infection among children aged 1- 5 years of Mayurbhanj district (Odisha), India: A prospective study protocol. [PDF]

open access: yesPLoS One
Bhat KD   +6 more
europepmc   +1 more source

Innovative pharmacotherapy for hepatic metabolic and chronic inflammatory diseases in China

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Liver disease constitutes a significant global health concern, particularly in China where it has distinctive characteristics. China grapples with a staggering 300 million cases, predominantly due to hepatitis B and metabolic non‐alcoholic fatty liver disease. Additionally, hepatocellular carcinoma has become a prevalent which is a lethal type
Feng Zhang   +5 more
wiley   +1 more source

Immunogenicity of an Intranasal Dual (Core and Surface)-Antigen Vaccine Against Hepatitis B Virus Enhanced by Carboxyl-Vinyl Polymer Excipients. [PDF]

open access: yesVaccines (Basel)
Rashid MHO   +15 more
europepmc   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

Organoid Models to Study Human Infectious Diseases

open access: yesCell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu   +4 more
wiley   +1 more source

NSun2‐Mediated tsRNAs Alleviate Liver Fibrosis via FAK Dephosphorylation

open access: yesCell Proliferation, EarlyView.
NSun2 deficiency inhibited sinusoidal capillarization, alleviating liver fibrosis. Reduced NSun2 expression led to alterations in the functional tsRNAs tRF‐1‐S25 and tRF‐5‐V31, which regulate sinusoidal capillarization by targeting key proteins, including DUSP1 and FAK – crucial clinical targets – offering a novel RNA‐based therapeutic approach for ...
Pengcheng Li   +14 more
wiley   +1 more source

The recent advances in vaccine adjuvants. [PDF]

open access: yesFront Immunol
Xing J   +6 more
europepmc   +1 more source

Endogenous Bacterial Endophthalmitis Complicating Hemodialysis Catheter‐Related Sepsis: A Case Report and Review of the Literature

open access: yesHemodialysis International, EarlyView.
ABSTRACT Background Endogenous endophthalmitis is an infrequent yet severe complication of hemodialysis catheter‐related sepsis. In this report, we present a case of endogenous bacterial endophthalmitis in a patient with hemodialysis catheter‐related sepsis.
Hui Guo   +5 more
wiley   +1 more source

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