Results 181 to 190 of about 75,183 (262)

Functional Antigen‐Specific CD8 TSCM Responses Are Associated with Repeated Clearance of Hepatitis C Virus Infection

open access: yesEuropean Journal of Immunology, Volume 55, Issue 12, December 2025.
HCV re‐infection is common after spontaneous clearance of the initial infection. In the rare group of super‐clearers who clear repeatedly, HCV‐specific CD8+ T memory stem cells (TSCM) retain stemness, proliferation, and multipotency, sustaining immune protection. In contrast, clearer chronics lose these properties.
Yanran Zhao   +10 more
wiley   +1 more source

The impact of two-year community-wide pharmacy interventions on the public's knowledge, attitudes, beliefs and behaviors about pharmacists as immunizers. [PDF]

open access: yesBMC Public Health
Halperin DM   +8 more
europepmc   +1 more source

IL‐10‐ and IL‐13‐Biased T Cell Responses to SARS‐CoV‐2 Vaccination in Diabetes

open access: yesEuropean Journal of Immunology, Volume 55, Issue 12, December 2025.
How the immune system of people with diabetes responds to vaccination against respiratory viruses is not well understood. Using activation‐induced markers to identify, quantify, and functionally characterize Spike‐specific CD4+ and CD8+ T cells after SARS‐CoV‐2 vaccination, we show defects in T cell memory maintenance and an IL‐10 and IL‐13‐dominated T
Emma M. Jones   +13 more
wiley   +1 more source

Dynamical Modelling and Optimal Control of Conjunctivitis Epidemic

open access: yesEngineering Reports, Volume 7, Issue 12, December 2025.
Conjunctivitis disease was modelled using a deterministic modelling approach, with the dynamics presented by the compartments in the flowchart. The results showed that intervention D is the best cost‐effectiveness policy. ABSTRACT In this study, we develop a mathematical model for conjunctivitis transmission dynamics.
Sacrifice Nana‐Kyere   +5 more
wiley   +1 more source

Efficacy of Hepatitis B vaccine in those who lost Hepatitis B surface antigen during follow-up: Efficacy of HBV vaccine in those who lost HBsAg.

open access: green, 2011
Hassan Taheri   +4 more
openalex   +1 more source

Recent Utilization of Pediatric Extrapolation and Modeling and Simulation Approaches in Pediatric Drug Development in Japan

open access: yesThe Journal of Clinical Pharmacology, Volume 65, Issue 12, Page 1889-1899, December 2025.
Abstract In Japan, the percentage of approved drugs with pediatric indications increased to 30% in 2010‐2015, but no further increase was observed through 2020. The Ministry of Health, Labor, and Welfare in Japan presented draft future directions to promote pediatric drug development, where the modeling and simulation (M&S) approach was introduced as a
Akinori Nakashima   +5 more
wiley   +1 more source

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