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Вопросы вирусологии, 2016 An update on the development and trials of synthetic peptide vaccines is reviewed. The review considers the successful examples of specific protection as a result of immunization with synthetic peptides using various protocols.
O. V. Sergeyev, I. F. Barinsky
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Immunogenicity and Protective Effects of an Ag85B Tuberculosis Subunit Vaccine Formulated with Synthetic TLR4 Agonists in BCG-Boosted Mice [PDF]
VaccinesBackground/Objectives: Tuberculosis (TB) remains a major global health challenge, and the Bacillus Calmette–Guérin (BCG) vaccine has limited efficacy against adult pulmonary disease. Protein subunit vaccines are a promising alternative but require strong
Soo-Min Kim +7 more
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Ecotoxicology and Environmental Safety, 2021 The widespread application of cadmium-free CuInS2/ZnS QDs has raised great concern regarding their potential toxicity to humans. To date, toxicological data related to CuInS2/ZnS QDs are scarce.
Zhiwen Yang +9 more
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Ecotoxicology and Environmental Safety, 2021 Increased applications of quantum dots (QDs) in the biomedical field have aroused attention for their potential toxicological effects. Although numerous studies have been carried out on the toxicity of QDs, their effects on reproductive and development ...
Li Li +9 more
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Chemical and Synthetic Biology Approaches for Cancer Vaccine Development
Molecules, 2022 Cancer vaccines have been considered promising therapeutic strategies and are often constructed from whole cells, attenuated pathogens, carbohydrates, peptides, nucleic acids, etc.
Farzana Hossain +4 more
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Cytotoxicity and Immune Dysfunction of Dendritic Cells Caused by Graphene Oxide
Frontiers in Pharmacology, 2020 Graphene, known as “black gold”, has important applications in various fields. In previous studies, it has been proved that graphene oxide (GO) which is a derivative of graphene has low toxicity.
Zhiwen Yang +8 more
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Synthetic peptide vaccines [PDF]
Biomeditsinskaya Khimiya, 2010 This review considers the stages of the development of synthetic peptide vaccines against infectious agents, novel approaches and technologies employed in this process, including bioinformatics, genomics, proteomics, large-scale peptide synthesis, high-throughput screening methods, the use of transgenic animals for modelling human infections.
A A, Moĭsa, E F, Kolesanova
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Vaccines, 2021 Vaccination is a key component of public health policy with demonstrated cost-effective benefits in protecting both human and animal populations. Vaccines can be manufactured under multiple forms including, inactivated (killed), toxoid, live attenuated ...
Majed Ghattas +3 more
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Development of synthetic antigen vaccines for COVID-19
Human Vaccines & Immunotherapeutics, 2021 The current pandemic called COVID-19 caused by the SARS-CoV-2 virus brought the need for the search for fast alternatives to both control and fight the SARS-CoV-2 infection.
Maria da Conceição Viana Invenção +7 more
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Proteome‐minimized outer membrane vesicles from Escherichia coli as a generalized vaccine platform
Journal of Extracellular Vesicles, 2021 Because of their potent adjuvanticity, ease of manipulation and simplicity of production Gram‐negative Outer Membrane Vesicles OMVs have the potential to become a highly effective vaccine platform.
Ilaria Zanella +18 more
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