Results 21 to 30 of about 1,223,155 (304)
Synthetic peptide vaccines [PDF]
Biomeditsinskaya Khimiya, 2010 This review considers the stages of the development of synthetic peptide vaccines against infectious agents, novel approaches and technologies employed in this process, including bioinformatics, genomics, proteomics, large-scale peptide synthesis, high-throughput screening methods, the use of transgenic animals for modelling human infections.
A A, Moĭsa, E F, Kolesanova
openaire +4 more sources
Adjuvants : an essential component of neisseria vaccines [PDF]
, 2009 Adjuvants may be classified into delivery systems and immune potentiator or modulator molecules based on their mechanism of action. Neisseria vaccines containing traditional adjuvants such as aluminium salts have existed for long time, but meningitis ...
Acevedo, R. +8 more
core +4 more sources
Vaccines, 2021 Vaccination is a key component of public health policy with demonstrated cost-effective benefits in protecting both human and animal populations. Vaccines can be manufactured under multiple forms including, inactivated (killed), toxoid, live attenuated ...
Majed Ghattas +3 more
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Development of synthetic antigen vaccines for COVID-19
Human Vaccines & Immunotherapeutics, 2021 The current pandemic called COVID-19 caused by the SARS-CoV-2 virus brought the need for the search for fast alternatives to both control and fight the SARS-CoV-2 infection.
Maria da Conceição Viana Invenção +7 more
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Synthetic vaccines targeting Mincle through conjugation of trehalose dibehenate
, 2022 The covalent fusion of immunostimulatory adjuvants to immunogenic antigens is a promising strategy for the development of effective synthetic vaccines for infectious diseases.
Ismanto, Hendra S +8 more
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Proteome‐minimized outer membrane vesicles from Escherichia coli as a generalized vaccine platform
Journal of Extracellular Vesicles, 2021 Because of their potent adjuvanticity, ease of manipulation and simplicity of production Gram‐negative Outer Membrane Vesicles OMVs have the potential to become a highly effective vaccine platform.
Ilaria Zanella +18 more
doaj +1 more source
Development of Streptococcus pneumoniae Vaccines Using Live Vectors [PDF]
, 2015 : Streptococcus pneumoniae still causes severe morbidity and mortality worldwide, especially in young children and the elderly. Much effort has been dedicated to developing protein-based universal vaccines to conquer the current shortcomings of capsular ...
core +1 more source
Synthetic carbohydrate-based vaccines: challenges and opportunities
Journal of Biomedical Science, 2020 Glycoconjugate vaccines based on bacterial capsular polysaccharides (CPS) have been extremely successful in preventing bacterial infections. The glycan antigens for the preparation of CPS based glycoconjugate vaccines are mainly obtained from bacterial ...
Ravinder Mettu +2 more
doaj +1 more source
Codon pair bias and viral vaccine design [PDF]
, 2015 The authors acknowledge the long term support of the Wellcome Trust and the Biotechnology and Biological Sciences Research Council.Live attenuated vaccines (LAVs) have prevented morbidity and mortality against a number of important viral diseases (such ...
Tulloch, Fiona Ashley +3 more
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Vaccines, 2014 Synthetic tumor vaccines have been proven to be promising for cancer immunotherapy. However, the limitation of the specificity and efficiency of the synthetic tumor vaccines need further improvements.
Zhi-Hua Huang +6 more
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