Results 31 to 40 of about 66,703 (260)
Immunological Evaluation of Recent MUC1 Glycopeptide Cancer Vaccines
Vaccines, 2016 Aberrantly glycosylated mucin 1 (MUC1) is a recognized tumor-specific antigen on epithelial cell tumors. A wide variety of MUC1 glycopeptide anti-cancer vaccines have been formulated by many research groups.
Md Kamal Hossain, Katherine A. Wall
doaj +1 more source
Potential of polymeric particles as future vaccine delivery systems/adjuvants for parenteral and non-parenteral immunization against tuberculosis: A systematic review [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective(s): Production of effective tuberculosis (TB) vaccine is necessity. However, the development of new subunit vaccines is faced with concerns about their weak immunogenicity. To overcome such problems, polymers-based vaccine delivery systems have
Farzad Khademi +3 more
doaj +1 more source
Overlapping synthetic peptides as vaccines
Vaccine, 2006 Several vaccine strategies aim to generate cell-mediated immunity (CMI) against microorganisms or tumors. While epitope-based vaccines offer advantages, knowledge of specific epitopes and frequency of major histocompatibility complex (MHC) alleles is required.
Jiang, S +4 more
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Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects
Advanced Materials, EarlyView.Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley +1 more source
Advancing mRNA technologies for therapies and vaccines: An African context
Frontiers in Immunology, 2022 Synthetic mRNA technologies represent a versatile platform that can be used to develop advanced drug products. The remarkable speed with which vaccine development programs designed and manufactured safe and effective COVID-19 vaccines has rekindled ...
Dylan Kairuz +4 more
doaj +1 more source
Advanced Materials, EarlyView.Inspired by viral entry mechanisms, the FUSION assay enables autonomous detection of respiratory viruses via membrane fusion–triggered CRISPR‐Cas13a activation. VEACON selectively fuses with fusion‐competent viruses, triggering fluorescence within confined vesicles.
Jae Chul Park +15 more
wiley +1 more source
The Use of Synthetic Carriers in Malaria Vaccine Design
Vaccines, 2015 Malaria vaccine research has been ongoing since the 1980s with limited success. However, recent improvements in our understanding of the immune responses required to combat each stage of infection will allow for intelligent design of both antigens and ...
Liam Powles +3 more
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Vaccines, 2023 The development of efficient fungal vaccines is urgent for preventing life-threatening systemic fungal infections. In this study, we prepared a synthetic, cell-based fungal vaccine for preventing systemic fungal infections using synthetic biology ...
Zirun Zhao +3 more
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Clustered carbohydrates in synthetic vaccines [PDF]
Chem. Soc. Rev., 2013 Are there general rules to obtain efficient immunization against carbohydrate antigens? Thanks to technological advances in glycobiology and glycochemistry we entered a new era in which the rational design of carbohydrate vaccines has become an achievable goal.
openaire +2 more sources