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Harnessing synthetic biology for advancing RNA therapeutics and vaccine design
npj Systems Biology and Applications, 2023 Recent global events have drawn into focus the diversity of options for combatting disease across a spectrum of prophylactic and therapeutic approaches. The recent success of the mRNA-based COVID-19 vaccines has paved the way for RNA-based treatments to ...
Blaine A. Pfeifer +4 more
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Synthetic Self-Adjuvanting Glycopeptide Cancer Vaccines
Frontiers in Chemistry, 2015 Due to changes in glycosyltransferase expression during tumorigenesis, the glycoproteins of cancer cells often carry highly truncated carbohydrate chains compared to those on healthy cells.
Richard James Payne +2 more
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New Points of Departure for More Global Influenza Vaccine Use
Vaccines, 2020 Each year, influenza causes a significant acute respiratory disease burden. In addition, influenza pandemics periodically occur. Annual vaccination is the best tool for influenza prevention, but its effectiveness can vary from year to year.
Irina Kiseleva
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Synthetic Vaccines from Tumor-Associated Glycopeptide Antigens
CHIMIA, 2011 The aberrantly glycosylated and extensively over-expressed membrane-bound mucin MUC1 glycoprotein forms a tumor specific epitope on the surface of epithelial cells.
Ulrika Westerlind, Horst Kunz
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Visceral Leishmaniasis: Advancements in vaccine development via classical and molecular approaches
Frontiers in Immunology, 2014 Visceral Leishmaniasis (VL) or kala-azar, a vector-borne protozoan disease, shows endemicity in larger areas of the tropical, subtropical and the Mediterranean countries.
Sumit eJoshi +5 more
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Advances in the design and development of SARS-CoV-2 vaccines
Military Medical Research, 2021 Since the end of 2019, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide.
Xue-Liang Peng +6 more
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Designing synthetic vaccines for HIV [PDF]
Expert Review of Vaccines, 2015 Despite three decades of intensive research efforts, the development of an effective prophylactic vaccine against HIV remains an unrealized goal in the global campaign to contain the HIV/AIDS pandemic. Recent characterization of novel epitopes for inducing broadly neutralizing antibodies has fueled research in the design and synthesis of new, well ...
Alberto Fernández-Tejada +2 more
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Synthetic Nanoparticles for Vaccines and Immunotherapy [PDF]
Chemical Reviews, 2015 1.1 Progress and challenges in the new age of engineering immunity The immune system plays a critical role in our health. No other component of human physiology plays a decisive role in as diverse an array of maladies, from deadly diseases with which we are all familiar to equally terrible esoteric conditions: HIV, malaria, pneumococcal and influenza ...
Rakhra, Kavya +3 more
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Acknowledgment to Reviewers of Vaccines in 2020
, 2021 Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Vaccines maintains its standards for the high quality of its published papers [...
Vaccines Editorial Office Vaccines Editorial Office
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Applications of polymer-based nanoparticles in vaccine field
Nanotechnology Reviews, 2019 Polymer-based nanoparticles have good solubility, stability, safety, and sustained release,which increases the absorption of loaded drugs, protects the drugs from degradation, and prolongs their circulation time and targeted delivery.
Guo Sihan +6 more
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