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Synthetic peptide vaccines
Вопросы вирусологии, 2016 An update on the development and trials of synthetic peptide vaccines is reviewed. The review considers the successful examples of specific protection as a result of immunization with synthetic peptides using various protocols.O. V. Sergeyev, I. F. Barinskydoaj +3 more sourcesSynthetic Nanoparticles for Vaccines and Immunotherapy [PDF]
Chemical Reviews, 2015 The immune system plays a critical role in our health. No other component of human physiology plays a decisive role in as diverse an array of maladies, from deadly diseases with which we are all familiar to equally terrible esoteric conditions: HIV ...Adamina M., Ahn S., Alizadeh D., Alvarez I. B., Amanna I. J., Amigorena S., Anderson R. P., Arias M. a, Ataman-Onal Y., Bachmann M. F., Bachmann M. F., Bagchi A., Bal S. M., Banchereau J., Barhate G., Barhate G., Beduneau A., Beeton C., Benson D. M., Bershteyn A., Bertholon I., Black M., Blander J. M., Blander J. M., Bonnaud C., Brandtzaeg P., Broaders K. E., Brode S., Brown J. M., Burchill M. A., Bures P., Cario E., Carrasco Y. R., Centers for Disease Control and Prevention, Cerutti A., Cha E., Chabot S., Chabot S. M., Chackerian B., Chackerian B., Champion J. A., Champion J. A., Chang L.-J., Choi J., Chou L. Y. T., Clark R. A., Couzin-Frankel J., Crespo J., Cruz L. J., Cu Y., Darrell J. Irvine, Davis M. E., Davis M. J., De Titta A., Demento S. L., Demento S. L., Demento S. L., Deretic V., Desai M. P., Di Giacomo A. M., Dijkstra J. A. N., Dintzis H. M., Dintzis R. Z., Diwan M., Dolina J. S., Dostert C., Dou H., Dou H., Dudeja P. K., Duivenvoorden R., Eisenbarth S. C., Elamanchili P., Endsley A. N., Ensign L. M., Ensign L. M., Fahmy T. M., Fang R. H., Fernandez-Urrusuno R., Fievez V., Fife B. T., Fifis T., Fifis T., Foged C., Franchi L., Fraser C. C., Freeling J. P., Friede M., Fröhlich E., Gallucci S., Gatto D., Gebril A., Gerner M. Y., Getts D. R., Gharagozloo M., Gilliet M., Glenn G. M., Grupp S. A., Gungor B., Gupta P. N., Gupta P. N., Hajdu P., Hamad I., Hamdy S., Hamdy S., Hanlon D. J., Hanniffy S. B., Hanson M. C., Harde H., Harding C. V., Harding C. V., Harris J., Hasegawa T., Hejazi R., Helling F., Himeno A., Hirosue S., Hodi F. S., Hoffmann E., Hornung V., Hu Y., Hu Y., Hunter Z., Huynh N. T., Ilyinskii P. O., Ingale S., Irvine D. J., Ishii M., Iwasaki A., Iwasaki A., Iwasaki A., Jain S., Jain S., Janeway C. A., Jewell C. M., Jin B., Joffre O. P., Jones M.-C., Junt T., Kamaly N., Kaminskas L. M., Kasturi S. P., Kavya Rakhra, Kawai T., Keller S., Kim Y.-M., Kinman L., Kitaoka M., Klavinskis L. S., Klebanoff C. A., Kolaczkowska E., Kool M., Kourtis I. C., Kovacsovics-Bankowski M., Kovacsovics-Bankowski M., Kuo-Haller P., Kuznetsov V. A., Kwong B., Kwong B., Lai S. K., Lanzavecchia A., Laroui H., Lee I. H., Leonard J. P., Leuschner F., Li A. V., Li A. V., Li H., Li N., Li P., Lico C., Liu H., Liu Z., Locke L. W., Look M., Look M., Lv H., Mabbott N. A., Macho Fernandez E., Maeda H., Maier T., Maisel K., Maldonado R. a., Mandraju R., Manolova V., Martinez F. O., Matzinger P., Matzinger P., Maus M. V., Mbow M. L., McKee A. S., McNamara J. O., Melissa C. Hanson, Mellman I., Mellman I., Minguet S., Minguet S., Mishra D., Mittal A., Modery-Pawlowski C. L., Moghimi S. M., Mohri K., Moon J. J., Moon J. J., Moon J. J., Morefield G. L., Movahedi K., Moyano D. F., Moyle P. M., Mueller S. N., Mukai Y., Muraoka D., Murray P. J., Nakamura T., Nakamura T., Napolitani G., Nehaus V., Nembrini C., Ni X., Niikura K., Niu L., Nochi T., Nordly P., Ochiel D. O., Okada E., Okazaki T., Oussoren C., Oyewumi M. O., Panelli M. C., Panzarini E., Park J., Park J., Pasare C., Perica K., Perisé-Barrios A. J., Petersen L. K., Phan T. G., Pinheiro M., Plapied L., Ralli-Jain P., Rancan F., Rappuoli R., Ravindran R., Reddy S. T., Reddy S. T., Reis e Sousa C., Restifo N. P., Riese P., Rodríguez-Limas W. a., Rosalia R. A., Rosalia R. A., Russell D. G., Sah H., Salata O., Salman H. H., Saluja S. S., Sanders M. T., Sarma J. V., Sawaengsak C., Scheerlinck J.-P. Y., Schietinger A., Seong S.-Y., Serramía M. J., Sharp F. a, Shen H., Sheridan B. S., Shi C., Shima F., Silva A. L., Slütter B., Slütter B., Smirnov D., Smith B. R., Smith B. R., Smith D. M., Sneh-Edri H., Snyder A., Soboll G., Sokolova V., Solbrig C. M., St. John A. L., Stano A., Stano A., Stano A., Stefanick J. F., Stefanick J. F., Steinman R. M., Stephan M. T., Stephan M. T., Stylianou E., Sun B., Tacken P. J., Takano S., Talar Tokatlian, Tanaka Y., Taneichi M., Tang R., Temchura V. V., Thomas S. N., Thornton E. E., Tobio M., Tomita Y., Topalian S. L., Torres A. G., Tsai S., Tsai S., Tsai S., Tsuji K., Turley D. M., Ulery B. D., Vajdy M., Van der Vlies A. J., Van Lehn R. C., Van ’t Klooster G., Vanlandschoot P., Vicente S., Villa C. H., Vinay D. S., Waeckerle-Men Y., Waeckerle-Men Y., Walter S., Wang C., Wang T., Wang Y.-Y., Wang Z., Watson D. S., Weber J., Wijagkanalan W., Williams G. R., Wilson J. T., Wira C. R., Woodrow K. a., Wright H. L., Wu T. Y., Xia Y., Xiao Y., Xing Y., Xu J., Xu L., Xu Q.-H., Yan S., Yates R. M., Yeaman G. R., Yee C., Yeh T.-H., Yeste a., Yu S. S., Yuan H., Yuba E., Yuba E., Zeltins A., Zeng R., Zhang S., Zhang Z., Zheng Y., Zhu Q., Zhu Q., Zoete M. R. De +356 morecore +5 more sourcesVirosome-formulated Plasmodium falciparum AMA-1 & CSP derived peptides as malaria vaccine: randomized phase 1b trial in semi-immune adults & children. [PDF]
, 2011 BACKGROUND\ud
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This trial was conducted to evaluate the safety and immunogenicity of two virosome formulated malaria peptidomimetics derived from Plasmodium falciparum AMA-1 and CSP in malaria semi-immune adults and children.\ud
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METHODS\ud
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The Abdallah, Mwanajaa Shomari, Abdulla, Salim, Aebi, Thomas, Cech, Patrick Georges, Daubenberger, Claudia, Genton, Blaise, Machunda, Ester Barnabas, Mpina, Maxmillian, Pluschke, Gerd, Stoffel, Sabine Alexandra, Tanner, Marcel, Westerfeld, Nicole, Zurbriggen, Rinaldo +12 morecore +16 more sourcesPEGylated CuInS2/ZnS quantum dots inhibit neurite outgrowth by downregulating the NGF/p75NTR/MAPK pathway
Ecotoxicology and Environmental Safety, 2021 The widespread application of cadmium-free CuInS2/ZnS QDs has raised great concern regarding their potential toxicity to humans. To date, toxicological data related to CuInS2/ZnS QDs are scarce.Zhiwen Yang, Wenyi Zou, Yongning Pan, Ken-Tye Yong, Li Li, Xiaomei Wang, Dongmeng Liu, Tingting Chen, Dahui Xue, Guimiao Lin +9 moredoaj +1 more sourceSystematic evaluation of CdSe/ZnS quantum dots toxicity on the reproduction and offspring health in male BALB/c mice
Ecotoxicology and Environmental Safety, 2021 Increased applications of quantum dots (QDs) in the biomedical field have aroused attention for their potential toxicological effects. Although numerous studies have been carried out on the toxicity of QDs, their effects on reproductive and development ...Li Li, Xiaotan Lin, Tingting Chen, Kan Liu, Yajing Chen, Zhiwen Yang, Dongmeng Liu, Gaixia Xu, Xiaomei Wang, Guimiao Lin +9 moredoaj +1 more sourceChemical and Synthetic Biology Approaches for Cancer Vaccine Development
Molecules, 2022 Cancer vaccines have been considered promising therapeutic strategies and are often constructed from whole cells, attenuated pathogens, carbohydrates, peptides, nucleic acids, etc.Farzana Hossain, Shruthi Kandalai, Xiaozhuang Zhou, Nan Zhang, Qingfei Zheng +4 moredoaj +1 more sourceCytotoxicity and Immune Dysfunction of Dendritic Cells Caused by Graphene Oxide
Frontiers in Pharmacology, 2020 Graphene, known as “black gold”, has important applications in various fields. In previous studies, it has been proved that graphene oxide (GO) which is a derivative of graphene has low toxicity.Zhiwen Yang, Yongning Pan, Tingting Chen, Li Li, Wenyi Zou, Dongmeng Liu, Dahui Xue, Xiaomei Wang, Guimiao Lin +8 moredoaj +1 more sourceSynthetic peptide vaccines [PDF]
Biomeditsinskaya Khimiya, 2010 This review considers the stages of the development of synthetic peptide vaccines against infectious agents, novel approaches and technologies employed in this process, including bioinformatics, genomics, proteomics, large-scale peptide synthesis, high-throughput screening methods, the use of transgenic animals for modelling human infections.A A, Moĭsa, E F, Kolesanovaopenaire +4 more sources