Results 11 to 20 of about 124,779 (298)

Synthetic peptide vaccines

open access: yesВопросы вирусологии, 2016
An update on the development and trials of synthetic peptide vaccines is reviewed. The review considers the successful examples of specific protection as a result of immunization with synthetic peptides using various protocols.
O. V. Sergeyev, I. F. Barinsky
doaj   +3 more sources

Immunogenicity and Protective Effects of an Ag85B Tuberculosis Subunit Vaccine Formulated with Synthetic TLR4 Agonists in BCG-Boosted Mice [PDF]

open access: yesVaccines
Background/Objectives: Tuberculosis (TB) remains a major global health challenge, and the Bacillus Calmette–Guérin (BCG) vaccine has limited efficacy against adult pulmonary disease. Protein subunit vaccines are a promising alternative but require strong
Soo-Min Kim   +7 more
doaj   +2 more sources

Synthetic Nanoparticles for Vaccines and Immunotherapy [PDF]

open access: yesChemical Reviews, 2015
The immune system plays a critical role in our health. No other component of human physiology plays a decisive role in as diverse an array of maladies, from deadly diseases with which we are all familiar to equally terrible esoteric conditions: HIV ...
Adamina M.   +356 more
core   +5 more sources

Virosome-formulated Plasmodium falciparum AMA-1 & CSP derived peptides as malaria vaccine: randomized phase 1b trial in semi-immune adults & children. [PDF]

open access: yes, 2011
BACKGROUND\ud \ud This trial was conducted to evaluate the safety and immunogenicity of two virosome formulated malaria peptidomimetics derived from Plasmodium falciparum AMA-1 and CSP in malaria semi-immune adults and children.\ud \ud METHODS\ud \ud The
Abdallah, Mwanajaa Shomari   +12 more
core   +16 more sources

PEGylated CuInS2/ZnS quantum dots inhibit neurite outgrowth by downregulating the NGF/p75NTR/MAPK pathway

open access: yesEcotoxicology and Environmental Safety, 2021
The widespread application of cadmium-free CuInS2/ZnS QDs has raised great concern regarding their potential toxicity to humans. To date, toxicological data related to CuInS2/ZnS QDs are scarce.
Zhiwen Yang   +9 more
doaj   +1 more source

Systematic evaluation of CdSe/ZnS quantum dots toxicity on the reproduction and offspring health in male BALB/c mice

open access: yesEcotoxicology and Environmental Safety, 2021
Increased applications of quantum dots (QDs) in the biomedical field have aroused attention for their potential toxicological effects. Although numerous studies have been carried out on the toxicity of QDs, their effects on reproductive and development ...
Li Li   +9 more
doaj   +1 more source

Chemical and Synthetic Biology Approaches for Cancer Vaccine Development

open access: yesMolecules, 2022
Cancer vaccines have been considered promising therapeutic strategies and are often constructed from whole cells, attenuated pathogens, carbohydrates, peptides, nucleic acids, etc.
Farzana Hossain   +4 more
doaj   +1 more source

Cytotoxicity and Immune Dysfunction of Dendritic Cells Caused by Graphene Oxide

open access: yesFrontiers in Pharmacology, 2020
Graphene, known as “black gold”, has important applications in various fields. In previous studies, it has been proved that graphene oxide (GO) which is a derivative of graphene has low toxicity.
Zhiwen Yang   +8 more
doaj   +1 more source

Synthetic peptide vaccines [PDF]

open access: yesBiomeditsinskaya Khimiya, 2010
This review considers the stages of the development of synthetic peptide vaccines against infectious agents, novel approaches and technologies employed in this process, including bioinformatics, genomics, proteomics, large-scale peptide synthesis, high-throughput screening methods, the use of transgenic animals for modelling human infections.
A A, Moĭsa, E F, Kolesanova
openaire   +4 more sources

Vaccine Technologies and Platforms for Infectious Diseases: Current Progress, Challenges, and Opportunities

open access: yesVaccines, 2021
Vaccination is a key component of public health policy with demonstrated cost-effective benefits in protecting both human and animal populations. Vaccines can be manufactured under multiple forms including, inactivated (killed), toxoid, live attenuated ...
Majed Ghattas   +3 more
doaj   +1 more source

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