Results 41 to 50 of about 124,779 (298)
Applications of polymer-based nanoparticles in vaccine field
Nanotechnology Reviews, 2019 Polymer-based nanoparticles have good solubility, stability, safety, and sustained release,which increases the absorption of loaded drugs, protects the drugs from degradation, and prolongs their circulation time and targeted delivery.
Guo Sihan +6 more
doaj +1 more source
Журнал микробиологии, эпидемиологии и иммунобиологии, 2016 For many decades, live vaccines remain the most effective means for prophylaxis of bacterial infections. Until recently, the main source of vaccine strains were empirically selected bacteria, virulence of which was attenuated due to natural mutations ...
A. V. Kolesnikov +6 more
doaj +1 more source
Human and bovine respiratory syncytial virus vaccine research and development [PDF]
, 2008 Human (HRSV) and bovine (BRSV) respiratory syncytial viruses (RSV) are two closely related viruses, which are the most important causative agents of respiratory tract infections of young children and calves, respectively.
Deplanche, Martine +2 more
core +2 more sources
An Update on mRNA-Based Viral Vaccines
Vaccines, 2021 With the success of COVID-19 vaccines, newly created mRNA vaccines against other infectious diseases are beginning to emerge. Here, we review the structural elements required for designing mRNA vaccine constructs for effective in vitro synthetic ...
Subbiah Jeeva +4 more
doaj +1 more source
Approaches to Improve Chemically Defined Synthetic Peptide Vaccines
Frontiers in Immunology, 2018 Progress made in peptide-based vaccinations to induce T-cell-dependent immune responses against cancer has invigorated the search for optimal vaccine modalities.
Brett J. Hos +3 more
doaj +1 more source
Frontiers in Immunology, 2022 Human cytomegalovirus (HCMV) is an ubiquitous herpesvirus that can cause serious morbidity and mortality in immunocompromised or immune-immature individuals.
Iris N. Pardieck +9 more
doaj +1 more source
Opportunities for integrated pest management to control the poultry red mite, Dermanyssus gallinae [PDF]
, 2011 Dermanyssus gallinae is the most economically important ectoparasite of laying hens in Europe. Control of D. gallinae is already hampered by issues of pesticide resistance and product withdrawal and, with the prohibition of conventional cages in 2012 and
COSOROABA I. +11 more
core +2 more sources
National Institute of Allergy and Infectious Diseases workshop report: "Chlamydia vaccines: The way forward". [PDF]
, 2019 Chlamydia trachomatis (Ct), an intracellular pathogen, is the most common bacterial sexually transmitted infection. In addition to acute cervicitis and urethritis, Ct can lead to serious sequelae of significant public health burden including pelvic ...
Brunham, Robert C +4 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Bacterial outer membrane vesicles and vaccine applications [PDF]
, 2014 Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Acevedo, Reinaldo +10 more
core +5 more sources