Results 1 to 10 of about 20,762,734 (419)
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
Nature, 2009 Jacques Fellay +2 more
exaly +2 more sources
Canadian Journal of Gastroenterology, 2000 Hepatitis C has been identified as the most common cause of post-transfusion hepatitis worldwide, accounting for approximately 90% of this disease in Japan, the United States and Western Europe. Hepatitis C is a major global public health problem. New infections continue to occur, and the source of infection includes transfusion of blood or blood ...
Daniel Lavanchy, Pilar Gavinio
+10 more sources
Versatile SARS-CoV-2 Reverse-Genetics Systems for the Study of Antiviral Resistance and Replication
Viruses, 2022 The COVID-19 pandemic continues to threaten healthcare systems worldwide due to the limited access to vaccines, suboptimal treatment options, and the continuous emergence of new and more transmissible SARS-CoV-2 variants.
Ulrik Fahnøe +11 more
doaj +1 more source
The Lancet, 2015 Hepatitis C virus (HCV) infection is a major health problem worldwide. The effects of chronic infection include cirrhosis, end-stage liver disease, and hepatocellular carcinoma. As a result of shared routes of transmission, co-infection with HIV is a substantial problem, and individuals infected with both viruses have poorer outcomes than do peers ...
Webster, D, Klenerman, P, Dusheiko, G
openaire +3 more sources
The Lancet, 1998 Hepatitis C virus (HCV) infection afflicts millions of people in the United States and worldwide. We examine the epidemiology of HCV infection, the molecular biology of the virus, the pathophysiology of infection, the clinical diagnosis and manifestations of infection, and the treatment of HCV infection.
T A, Morton, G D, Kelen
+10 more sources
mSphere, 2022 The International Liver Association recommends the use of accurate and sensitive molecular methods for determination of hepatitis B virus (HBV) DNA levels in plasma or serum of chronic HBsAg carriers. The level of HBV replication represents the strongest
Valérie Ortonne +7 more
doaj +1 more source
Viruses, 2021 Liver steatosis is a common complication of chronic hepatitis C virus (HCV) infection, which can result in accelerated liver fibrosis development, especially in patients infected with genotype 3a.
Andrea Galli +2 more
doaj +1 more source
BMC Medical Genetics, 2020 Background Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease worldwide. Current studies have shown that PNPLA3 (Patatin-like phospholipase domain containing 3) rs738409 G/C gene polymorphism is associated ...
Shan Tang +13 more
doaj +1 more source
In vitro efficacy of artemisinin-based treatments against SARS-CoV-2
Scientific Reports, 2021 Effective and affordable treatments for patients suffering from coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are needed.
Yuyong Zhou +13 more
doaj +1 more source
SARS-CoV-2 Production in a Scalable High Cell Density Bioreactor
Vaccines, 2021 The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has demonstrated the value of pursuing different vaccine strategies. Vaccines based on whole viruses, a widely used vaccine technology, depend on efficient virus production.
Anna Offersgaard +14 more
doaj +1 more source