Results 141 to 150 of about 159,244 (259)

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

A systematic review on nutraceuticals as a potential source of therapeutics against COVID-19 and other emerging viral diseases

Discover Applied Sciences
COVID-19 is a respiratory viral disease caused by acute respiratory syndrome coronavirus (SARS-CoV) that resulted in a significant pandemic. There is currently no effective antiviral medication to fight the deadly and extremely contagious COVID-19 virus.
Pankaj Singh, Fareha Rayeen, Roli Singh, Manikant Tripathi, Pradeep Kumar Singh, Saba Ubaid, Neelam Pathak   +6 more
doaj   +1 more source

Viral Infections Associated with Anemia

Novelty in Biomedicine
Background: Anemia is a serious blood disorder characterized by the bone marrow's inability to produce new blood cells, which can be either acquired or inherited.
Seyed Gholamreza Azimi, Hossein Goudarzi, Ebrahim Faghihloo   +2 more
doaj   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Unmasking Hepatitis A: A Case Study of Atypical Presentation in a Returning Traveler From Egypt

Case Reports in Hepatology
Hepatitis, characterized by inflammation of the liver, arises from various infectious and noninfectious causes, with viral hepatitis being caused by a diverse group of viruses including hepatitis A, B, C, D, and E.
Emmanuel Edwar Siddig, Claude M. Muvunyi, Ayman Ahmed   +2 more
doaj   +1 more source

Cuproptosis‐Related Genes in Immune Infiltration and Diagnosis in Hepatitis B Virus‐Related Acute Liver Failure

Exploration, EarlyView.
The role of cuproptosis in HBV‐ALF was explored via bioinformatics and liver biopsy tissues. There are some crosstalks among cuproptosis, immune infiltration, and ferroptosis (The figure was created by Bio Render). ABSTRACT Hepatitis B virus (HBV) infection poses a significant challenge to global health, particularly in developing countries such as ...
Jingwen Deng, Tao Zhu, Yueyang Wang, Sitong Zhang, Hong Deng, Guilan Quan, Tingting Peng, Chuanbin Wu, Huiqiang Cai, Chao Lu, Xiaopeng Cai   +10 more
wiley   +1 more source

Microengineering the Liver: Strategies for Constructing Functional Liver‐on‐a‐Chip Devices

Exploration, EarlyView.
This review summarizes recent advances in liver‐on‐a‐chip (LOC) technologies, including fabrication strategies and functional integration approaches, and discusses their promising applications in drug screening and related biomedical fields. ABSTRACT Reliable in vitro liver models are indispensable for researching liver diseases and developing ...
Jie Wang, Ziwei Liang, Jiapu Wang, Zongyi Li, Shaojie Wang, Yan Wei, Xin Xie, Di Huang   +7 more
wiley   +1 more source

Progress on the Protective Effect and the Mechanism of Chinese Medicine Injection and Chinese Medicine Monomeric Small Molecules on Sepsis‐Related Liver Injury

Gut Medicine, EarlyView.
ABSTRACT Sepsis‐related liver injury (SRLI) involves multiple interrelated pathological processes, including excessive inflammation, oxidative imbalance, mitochondrial dysfunction, dysregulated autophagy, and microcirculatory impairment. Increasing evidence indicates that traditional Chinese medicine (TCM)–based interventions, particularly Chinese ...
Xiang Yunsheng, Yan Yumeng
wiley   +1 more source

HIV-Now Another Long Term Chronic Condition? [PDF]

Viruses
Tang JW, Olszyna DP, Stephenson I, Archuleta S.   +3 more
europepmc   +1 more source

Crosstalk between vimentin and keratins in viral infection: Implications across the viral life cycle. [PDF]

Virulence
Lu X, Wang X, Liu X, Liu X.
europepmc   +1 more source