N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen +6 more
wiley +1 more source
Diverse novel and avian-associated viruses in the ileal viromes of Northern Mockingbird (Mimus polyglottos). [PDF]
Bourke BP +4 more
europepmc +1 more source
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi +6 more
wiley +1 more source
Advances in Rapid Nucleic Acid Diagnostics for Hepatitis B and C Viruses: A Comprehensive Review. [PDF]
Ho HY +6 more
europepmc +1 more source
We detect the risk factors and image characteristics of incidentally detected IAAD. Independent risk factors of IAAD included fatty liver and smoking. In the ultrasound findings of IAAD, an intimal flap was frequently observed. In the CT scan, displacement of intimal calcifications was frequently observed. For suspected IAAD, the abdominal aorta should
Hiromasa Tsubouchi +15 more
wiley +1 more source
Hepatic Viral Reservoirs in Concurrent HIV and HBV: From Mechanistic Insight to Integrated Cure Strategies. [PDF]
Bobadilla R +4 more
europepmc +1 more source
Site-specific alteration of murine hepatitis virus type 4 peplomer glycoprotein E2 results in reduced neurovirulence [PDF]
Buchmeier, M J +3 more
core
Reframing Post‐Hepatectomy Liver Failure as a Determinant of Post‐Recurrence Survival in HCC
ABSTRACT Background Post‐hepatectomy liver failure (PHLF) is traditionally considered a transient perioperative complication with limited long‐term consequences, yet its long‐term oncologic implications in hepatocellular carcinoma (HCC) remain unclear. Methods Patients undergoing primary hepatectomy for HCC between 2007 and 2018 were analyzed.
Hiroshi Horie +7 more
wiley +1 more source
Construction and characterization of recombinant duck enteritis virus expressing duck hepatitis A virus 3 immunogenic genes. [PDF]
Jia W +10 more
europepmc +1 more source

