Force for ancient and recent life: viral and stem-loop RNA consortia promote life. [PDF]
Lytic viruses were thought to kill the most numerous host (i.e., kill the winner). But persisting viruses/defectives can also protect against viruses, especially in a ubiquitous virosphere. In 1991, Yarmolinsky et al.
Villarreal, Luis P
core +1 more source
HCV infection in northeastern Brazil: unexpected high prevalence of genotype 3a and absence of African genotypes [PDF]
The genomic diversity of HCV embraces 6 genotypes and at least 52 subtypes with clinical and epidemiological correlations. There is a paucity of studies assessing HCV genotypes and biomolecular epidemiology in Brazil. We studied genotype distribution and
Raymundo PARANÁ +7 more
doaj
Aetiology and Clinical Profile of Infectious Causes of Febrile Jaundice at a Tertiary Care Hospital in Eastern Odisha- An Observational Prospective Study [PDF]
Introduction: Fever with jaundice is one of the most common presentations seen in both outdoor and indoor patients. This manifestation is seen in many individuals infected with hepatotropic viruses (A to E), bacteria, protozoa, fungi, and non ...
Chaitanya Teja Annam +3 more
doaj +1 more source
HDV can constrain HBV genetic evolution in hbsag: Implications for the identification of innovative pharmacological targets [PDF]
Chronic HBV + HDV infection is associated with greater risk of liver fibrosis, earlier hepatic decompensation, and liver cirrhosis hepatocellular carcinoma compared to HBV mono-infection.
Andreoni, Massimo +34 more
core +2 more sources
Viral Hepatitis - The Road Traveled and the Journey Remaining
Ghulam Fareed Malik,1 Noval Zakaria,1 Muhammad Ibrahim Majeed,2 Faisal Wasim Ismail1 1Section of Gastroenterology, Department of Medicine, The Aga Khan University, Karachi, Pakistan; 2Medical College, The Aga Khan University, Karachi ...
Malik GF +3 more
doaj
Recombinant Flag-tagged E1E2 glycoproteins from three hepatitis C virus genotypes are biologically functional and elicit cross-reactive neutralizing antibodies in mice [PDF]
Hepatitis C virus (HCV) is a globally disseminated human pathogen for which no vaccine is currently available. HCV is highly diverse genetically and can be classified into 7 genotypes and multiple sub-types. Due to this antigenic variation, the induction
Bieńkowska-Szewczyk, Krystyna +5 more
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Viruses in Horses with Neurologic and Respiratory Diseases. [PDF]
Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Altan, Eda +7 more
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Protective efficacy of serially up-ranked subdominant CD8+ T cell epitopes against virus challenges.
Immunodominance in T cell responses to complex antigens like viruses is still incompletely understood. Some data indicate that the dominant responses to viruses are not necessarily the most protective, while other data imply that dominant responses are ...
Eung-Jun Im +9 more
doaj +1 more source
Hepatitis B Virus (HBV) and S-Escape Mutants: From the Beginning until Now [PDF]
Despite of the progress made in vaccine and antiviral therapy development, hepatitis B virus (HBV) infection remains a major health care problem. More than 240 million people are chronically infected worldwide showing differences in the severity of liver
Cuestas, María Luján +4 more
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Immunotherapy and Gene Therapy for Oncoviruses Infections: A Review
Immunotherapy has been shown to be highly effective in some types of cancer caused by viruses. Gene therapy involves insertion or modification of a therapeutic gene, to correct for inappropriate gene products that cause/may cause diseases.
Nathália Alves Araújo de Almeida +3 more
doaj +1 more source

