Results 91 to 100 of about 912,101 (303)

Development of a Norway rat hepacivirus reporter for high-throughput quantification of neutralizing antibodies

Journal of Virology
Hepatitis C virus (HCV) remains a major global health challenge, with vaccine research hindered by a lack of robust immunocompetent animal models.
Matthew J. Kennedy, Raphael Wolfisberg, Emma A. Lundsgaard, Caroline E. Thorselius, Laura Collignon, Louise Nielsen, Kenn Holmbeck, Jens Bukh, Troels K. H. Scheel   +8 more
doaj   +1 more source

Impact of TP53 Codon 72 and MDM2 Promoter 309 Allelic Dosage in a Moroccan Population with Hepatocellular Carcinoma

The International Journal of Biological Markers, 2011
Single-nucleotide polymorphisms (SNPs) in codon 72 of the TP53 gene (rs1042522) and in the promoter region of the MDM2 gene (SNP309; rs2279744) have been shown to play a role in the predisposition to many cancers.
Sayeh Ezzikouri, Abdellah Essaid El Feydi, Rajae Afifi, Mustapha Benazzouz, Mohammed Hassar, Pascal Pineau, Soumaya Benjelloun   +6 more
doaj   +1 more source

Functional Interplay between RNA Viruses and Non-Coding RNA in Mammals

Non-Coding RNA, 2019
Exploring virus–host interactions is key to understand mechanisms regulating the viral replicative cycle and any pathological outcomes associated with infection.
Nkerorema Djodji Damas, Nicolas Fossat, Troels K. H. Scheel   +2 more
doaj   +1 more source

Hepatitis B/C virus co-infection in Iran: A seroepidemiological study [PDF]

, 2007
Background/aims: As hepatitis B and C virus have the same transmission routes, dual infection may occur. The aim of this study was to determine the seroprevalence of HCV in HBsAg-positive subjects.
Abdolahi, N., Besharat, S., Danesh, A., Hosseini, S.A., Jabbari, A., Joshaghani, H., Kabir, M.J., Kalavi, K., Keshtkar, A.A., Moradi, A., Roshandel, D., Roshandel, G., Sedaqat, S.M., Semnani, S.   +13 more
core  

Dentistry and the ethics of infection [PDF]

, 2008
Currently, any dentist in the UK who is HIV-seropositive must stop treating patients. This is despite the fact that hepatitis B-infected dentists with a low viral load can continue to practise, and the fact that HIV is 100 times less infectious than ...
Shaw, D.M.
core   +1 more source

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

Advanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao, Jianwen Jiang, Ruiqing Zhang, Dongya Zhang, Chenchen Zhang, Ang Li, Haifeng Lu, Hua Zhang, Lin Zhou, Wenzhi Guo, Peihao Wen, Jianfeng Xue, Jie Pan, Tuerganaili Aji, Zhou Lan, Xianzhi Jiang, Shusen Zheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

Hepatitis C [PDF]

Journal of Midwifery & Women's Health, 2021
openaire   +2 more sources

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study [PDF]

, 2018
Background/Aims: The hepatitis C virus (HCV) infection is important cause of chronic hepatitis. Liver biopsy is considered the gold standard for assessment of fibrosis but this procedure is an invasive procedure.
Akhan, S., Aydoǧdu, Ö., Baykam, N., Beslen, N., Bostanci, F., Candan, M., Daǧli, Ö., Demirdal, T., Duyar, E., Erdoǧan, S., Gökal, A.A., Güner, R., Gürbüz, Y., Inan, D., Kaya, A., Kaya, S., Kiliç, S., Kinikli, S., Kuruüzüm, Z., Kökoǧlu, Ö.F., Köksal, I., Leblebicioǧlu, H., Namiduru, M., Parlak, M., Sehmen, E., Tabak, F., Tarakçi, H., Turgut, Hüseyin, Ural, O., Yamazhan, T., Yilmaz, G., Yuluǧkural, Z., Önlen, Y., Özdemir, D., Özdener, F.   +34 more
core   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source