Results 101 to 110 of about 912,101 (303)

Hepatitis C infection and associated oral health problems [PDF]

open access: yes, 2000
The document attached has been archived with permission from the Australian Dental Association. An external link to the publisher’s copy is included.Hepatitis C infection is widespread throughout the community.
Ainamo J.   +13 more
core   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei   +11 more
wiley   +1 more source

Abl Tyrosine Kinase Regulates Hepatitis C Virus Entry

open access: yesFrontiers in Microbiology, 2017
Abl is a central regulator of multiple cellular processes controlling actin dynamics, proliferation, and differentiation. Here, we showed that knockdown of Abl impaired hepatitis C virus (HCV) propagation.
Saehong Min   +11 more
doaj   +1 more source

Vitamin D as One of Predicators of the Stable Viral Response to Antiviral Therapy in Patients with Chronis Hepatitis С [PDF]

open access: yes, 2016
Chronic hepatitis C (CHC) it is not exceptionally medical problem but a significant social and economic threat, taking into account the unfavorable consequences of this disease: cirrhosis and hepatocellular carcinoma.
Androsova, O. (Olga)   +3 more
core  

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

open access: yesAdvanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen   +12 more
wiley   +1 more source

IL28B is associated with outcomes of chronic HBV infection [PDF]

open access: yes, 2015
Purpose The role of IL28B gene variants and expression in hepatitis B virus (HBV) infections are not well understood. Here, we evaluated whether IL28B gene expression and rs12979860 variations are associated with HBV outcomes.
Chi, Xiumei   +11 more
core   +1 more source

Consumed by Abdominal Distention

open access: yes
Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge   +3 more
wiley   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

Audit of Antenatal Testing of Sexually Transmissible Infections and Blood Borne Viruses at Western Australian Hospitals [PDF]

open access: yes, 2008
In August 2007, the Western Australian Department of Health (DOH) released updated recommendations for testing of sexually transmissible infections (STI) and blood-borne viruses (BBV) in antenates.
Combs, B. G.   +3 more
core   +1 more source

Modulation of triglyceride and cholesterol ester synthesis impairs assembly of infectious hepatitis C virus [PDF]

open access: yes, 2014
In hepatitis C virus infection, replication of the viral genome and virion assembly are linked to cellular metabolic processes. In particular, lipid droplets, which store principally triacylglycerides (TAGs) and cholesterol esters (CEs), have been ...
Hague, Charlotte V.   +4 more
core   +1 more source

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