Results 71 to 80 of about 778,157 (293)
Abl Tyrosine Kinase Regulates Hepatitis C Virus Entry
Abl is a central regulator of multiple cellular processes controlling actin dynamics, proliferation, and differentiation. Here, we showed that knockdown of Abl impaired hepatitis C virus (HCV) propagation.
Saehong Min+11 more
doaj +1 more source
Influence of Intracellular Delay on the Dynamics of Hepatitis C Virus [PDF]
In this paper we present a delay induced model for hepatitis C virus incorporating the healthy and infected hepatocytes as well as infectious and noninfectious virions. The model is mathematically analyzed and characterized, both for the steady states and the dynamical behavior of the model.
arxiv
This study uses gut microbiome data to predict corticosteroid response in patients with immune thrombocytopenia (ITP). Fecal samples from 212 patients with ITP are sequenced. Six machine‐learning algorithms are used to train predictive models. The support vector machine‐based model integrated clinical data and selected microbial species, diversities ...
Feng‐Qi Liu+38 more
wiley +1 more source
Virus removal from aqueous environments with polyelectrolyte coatings on a polypropylene fleece
We present three methods to immobilize heparin‐mimicking, virus‐binding polymers on filter materials. Linear polyglycerol sulfate is grafted to the surface either via mussel‐inspired coating chemistry, or by using a benzophenone anchor. Herpes simplex virus type 1 and severe acute respiratory virus 2 are efficiently removed from solution upon ...
Maiko Schulze+6 more
wiley +1 more source
Antigen‐Targeting Inserted Nanomicelles Guide Pre‐Existing Immunity to Kill Head and Neck Cancer
This study introduces a tumor‐targeted nanomicelle platform (preS1‐pHLIP) that exploits pre‐existing antiviral immunity to combat heterogeneous cancers. By delivering viral antigens to label tumors as virus‐like targets, the nanomicelles activate antiviral B and T cells, triggering in situ tumor lysis.
Lizhuo Zhang+16 more
wiley +1 more source
Background/Purpose: This study aims at investigating the epidemiological profile of chronic hepatitis C (CHC) regarding hepatitis C virus (HCV) genotype in Taiwan.
Grace Hui-Min Wu+8 more
doaj
Mathematical analysis of an extended cellular model of the Hepatitis C Virus infection with non-cytolytic process [PDF]
The aims of this work is to analyse of the global stability of the extended model of hepatitis C virus(HCV) infection with cellular proliferation, spontaneous cure and hepatocyte homeostasis. We first give general information about hepatitis C. Secondly, We prove the existence of local, maximal and global solutions of the model and establish some ...
arxiv
Early detection of hepatocellular carcinoma in patients with liver cirrhosis and/or hepatitis virus B/C infection improves survival. Through marker discovery, 8 methylated DNA markers are identified and a logistic regression model (COMET‐LR) is built in the training set, which achieved 90.0% sensitivity at 97.4% specificity in the validation set.
Tian Yang+16 more
wiley +1 more source
Background & Aims: Hepatitis C virus (HCV) is a leading cause of chronic liver diseases and the most common indication for liver transplantation in the United States.
Ursula Andreo+10 more
doaj
An Effective Evolutionary Clustering Algorithm: Hepatitis C Case Study [PDF]
Clustering analysis plays an important role in scientific research and commercial application. K-means algorithm is a widely used partition method in clustering. However, it is known that the K-means algorithm may get stuck at suboptimal solutions, depending on the choice of the initial cluster centers. In this article, we propose a technique to handle
arxiv