Results 31 to 40 of about 283,567 (361)

Recombinant Flag-tagged E1E2 glycoproteins from three hepatitis C virus genotypes are biologically functional and elicit cross-reactive neutralizing antibodies in mice [PDF]

, 2018
Hepatitis C virus (HCV) is a globally disseminated human pathogen for which no vaccine is currently available. HCV is highly diverse genetically and can be classified into 7 genotypes and multiple sub-types. Due to this antigenic variation, the induction
Bieńkowska-Szewczyk, Krystyna, Chmielewska, Alicja, Krapchev, Vasil B., Patel, Arvind H., Rychłowska, Malgorzata, Zimmer, Karolina   +5 more
core   +1 more source

IgG1 and IgG4 antibodies against Core and NS3 antigens of hepatitis C virus

Revista da Sociedade Brasileira de Medicina Tropical, 2019
INTRODUCTION: IgG subclasses involved in the immune response to hepatitis C virus (HCV) antigens have been rarely studied. We investigated the immune response mediated by IgG1 and IgG4 antibodies against the recombinant core and NS3 antigens in patients
Vanessa Costa dos Santos, Maria Isabel Schinoni, Isabela Silva de Oliveira, Maria Luiza Sousa Atta, Ajax Mercês Atta   +4 more
doaj   +1 more source

Hepatitis B Virus (HBV) and S-Escape Mutants: From the Beginning until Now [PDF]

, 2015
Despite of the progress made in vaccine and antiviral therapy development, hepatitis B virus (HBV) infection remains a major health care problem. More than 240 million people are chronically infected worldwide showing differences in the severity of liver
Cuestas, María Luján, Eguibar, Nair, Gonzalez, Rodrigo Horacio, Nusblat, Alejandro David, Perazzo, Priscila   +4 more
core   +1 more source

Seroprevalence and clinico-epidemiological correlates of hepatitis c infection in pregnancy at a booking antenatal clinic, federal medical centre, Yenagoa

Nigerian Journal of Medicine, 2018
BACKGROUND: World health organization estimated that approximately 170 million people are infected with Hepatitis C virus with about 130 million being carriers, three to four million persons are newly infected in each year and more than 350,000 people ...
E L Kotingo, D O Allagoa, J E Omietimi, E O S Aigere, P W Oweisi, C T John   +5 more
doaj   +1 more source

Immune response to vaccines in children with celiac disease [PDF]

, 2017
Celiac disease (CD) is an immune-mediated systemic condition evoked by ingestion of gluten and related prolamines in genetically susceptible subjects. The disease is featured by a variable combination of clinical signs, specific antibodies, HLA-DQ2 and ...
ANANIA, Caterina, CHIESA, CLAUDIO, OLIVERO, FRANCESCA, PACIFICO, Lucia, Spagnolo, Alessandra   +4 more
core   +1 more source

Adverse reactions of biological therapies in patients with psoriasis [PDF]

, 2017
Psoriasis is a chronic, immune-mediated disorder characterized by well demarcated, erythematous plaques covered by thick, silvery-white scales, most often located on the knees, elbows, sacral area and scalp.
Georgescu, Simona R., Limbău, Alexandra M., Mitran, Cristina I., Mitran, Mădălina I., Sârbu, Maria I., Tampa, Mircea   +5 more
core   +7 more sources

Clinical Outcomes of Patients Within the Rheumatoid Arthritis Care Pathway Cohort at a Tertiary Care Integrated Delivery Network: A Comparison to Usual Care

Arthritis Care &Research, EarlyView.
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multidisciplinary team‐based care.
Tarun Sharma, Tyson S. Barrett, Teigan Dwyer, Nancy Campbell, Jessica Heintzinger, Ellen Kraemer, Adam Dore, Susan Manzi   +7 more
wiley   +1 more source

Prevalence of antibodies to Hepatitis C virus among Nigerian patients with HIV infection [PDF]

, 2005
Nigeria belongs to the group of countries highly endemic for viral hepatitis; unfortunately information on the prevalence of hepatitis C amongst patients with HIV in Nigeria is very scarce.
Chigozie Jesse Uneke, Greg Ike Anyanwu, John Alechenu Idoko, Julia Hauwa Idoko, Okonkwo Moses Njoku, Petrus Uchenna Inyama   +5 more
core   +1 more source

Incidence, prevalence, and clinical course of hepatitis C following liver transplantation [PDF]

, 1992
Hepatitis C virus (HCV) is the agent responsible for posttransfusion hepatitis. The incidence, timing, and clinical course of HCV positive hepatitis in liver transplant recipients are unknown.
A.Jake Demetris, Aach, Alter, Barcena, Barrera, Brillanti, Choo, Colombo, David H. Van Thiel, Esteban, Esteban, Feinman, Grandele, Gray, Gunjan Shah, Hernandez, Jessica H. Lewis, Judith S. Gavaler, Kaplan, Knodell, Kuo, Kühnl, Mattsson, McFarlane, McHutchison, Noel, Poel, Read, Read, Rumi, Saturo Todo, Simonetti, Stevens, Thomas E. Starzl, Trainer, Weiner   +35 more
core   +1 more source

Clinical Conditions Associated With a High Antinuclear Antibody Titer in Individuals Without Autoimmune Disease

Arthritis Care &Research, EarlyView.
Objective Antinuclear antibodies (ANAs) are present at high titers in 2% of the general population, but their clinical significance in individuals without an autoimmune (AI) disease is not known. We tested the hypothesis that the presence of a high ANA titer in non‐AI conditions is associated with disease.
Matthew Chung, John P. Shelley, Gul Karakoc, John Still, Xiaodi Ruan, Jonathan Mosley, C. Michael Stein, Vivian K. Kawai   +7 more
wiley   +1 more source