Results 61 to 70 of about 283,567 (361)

The prevalence of hepatitis C virus among people of South Asian origin in Glasgow: results from a community based survey and laboratory surveillance [PDF]

, 2013
Background South Asians often present late with HCV or HBV related liver disease which could have been avoided with early diagnosis and subsequent treatment; however the prevalence of HCV/HBV among South Asians in Glasgow is not known.
Ahmed, S., Anderson, Eleanor, Banday, Shabir, Cameron, Sheila, Foster, Graham R., Fox, Ray, Goldberg, David, Hutchinson, Sharon J., McLeod, Allan, McTaggart, Christine, Mills, Peter R., O'Leary, Maureen C., Sarwar, Mohammed, Schofield, Joe, Weir, Amanda   +14 more
core   +2 more sources

Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis

Advanced Science, EarlyView.
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu, Chen Su, Jianling Liu, Mingyan Xing, Xiaoxia Wu, Lingxia Wang, Xiaoming Zhao, Hanwen Zhang, YangYang Xie, YangYang Wang, Hong Li, Yu Li, Ming Li, Haibing Zhang   +13 more
wiley   +1 more source

Screening vertical transmission of infections during pregnancy: Toxoplasmosis, HIV, Hepatitis B and C, Syphilis

Kasmera, 2016
The screening for infection diseases in pregnancy by laboratory tests can reduce the risk of perinatal and maternal morbidity and mortality. The objective of this study was to identify the presence of vertically transmitted infections: toxoplasmosis, HIV,
A Avila, M Gómez, E Castillo, M Guerra, Y Alvarez, K Bastiste, M Carrasco   +6 more
doaj  

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Seroprevalence of viral hepatitis A, B, C, D and E viruses in the Hormozgan province southern Iran

BMC Infectious Diseases, 2019
Background Viral hepatitis is a global public health problem affecting millions of people worldwide, causing thousands of deaths due to acute and persistent infection, cirrhosis, and liver cancer.
Mohammad Amin Behzadi, Victor Hugo Leyva-Grado, Mandana Namayandeh, Atoosa Ziyaeyan, Roya Feyznezhad, Hedayat Dorzaban, Marzieh Jamalidoust, Mazyar Ziyaeyan   +7 more
doaj   +1 more source

Hepatitis C–associated focal proliferative glomerulonephritis in an aviremic recipient of a hepatitis C–positive antibody donor liver [PDF]

, 2021
Humberto Bohórquez, Juan Carlos Q. Velez, Mark A. Lusco, Jennifer Scheuermann, Ari Cohen   +4 more
openalex   +1 more source

Viral Hepatitis and Rapid Diagnostic Test Based Screening for HBsAg in HIV-infected Patients in Rural Tanzania. [PDF]

, 2013
\ud \ud Co-infection with hepatitis B virus (HBV) is highly prevalent in people living with HIV in Sub-Saharan Africa. Screening for HBV surface antigen (HBsAg) before initiation of combination antiretroviral therapy (cART) is recommended. However, it is
AM Geretti, AP Kourtis, AS Lok, Bernadeta Msongole, BH Tess, Bruno Verhasselt, Christoph Hatz, CJ Hoffmann, CJ Hoffmann, CL Thio, D Nash, E Mossdorf, E Stahel, ED Chan, Emilio Letang, F Randrianirina, Fabian C. Franzeck, Geoffrey Mwaigomole, GV Matthews, J Davies, J Jaroszewicz, J Li, L Martin-Carbonero, L Stabinski, Lars Henning, M Nyirenda, MA Thompson, Manuel Battegay, Marcel Tanner, Marian Hamisi, MC Kew, Omary Abdul, PM Bossuyt, R Weber, Ramadhani Ngwale, TEMS de Vries–Sluijs, TJ Nagu   +36 more
core   +4 more sources

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Challenge pools of hepatitis C virus genotypes 1-6 prototype strains: replication fitness and pathogenicity in chimpanzees and human liver-chimeric mouse models [PDF]

, 2010
Chimpanzees represent the only animal model for studies of the natural history of hepatitis C virus (HCV). To generate virus stocks of important HCV variants, we infected chimpanzees with HCV strains of genotypes 1-6 and determined the infectivity titer ...
Bukh, Jens, Eder, Gerald, Engle, Ronald E, Feinstone, Stephen M, Govindarajan, Sugantha, Krawczynski, Krzysztof, Leroux-Roels, Geert, Meuleman, Philip, Miller, Roger H, Purcell, Robert H, Satterfield, William C, Tellier, Raymond   +11 more
core   +1 more source