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Hepatic peroxisome proliferator-activated receptor γ and α-mRNA expression in HCV-infected adults is decreased by HIV co-infection and is also affected by ethnicity [PDF]

open access: yesClinics, 2015
OBJECTIVE: To determine peroxisome proliferator activated receptor α and γ mRNA expression in liver tissue of hepatitis C virus-infected patients with and without human immunodeficiency virus and its possible contribution to an acceleration of liver ...
Nathan J. Shores   +6 more
doaj   +5 more sources

Opportunities and Challenges: Hepatitis C Testing and Treatment Access Experiences Among People in Methadone and Buprenorphine Treatment During COVID-19, Arizona, 2021

open access: yesAJPM Focus, 2023
Introduction: The purpose of this study was to characterize hepatitis C virus screening and treatment access experiences among people in treatment for opioid use disorder in Arizona during COVID-19.
Beth E. Meyerson, PhD   +13 more
doaj   +3 more sources

‘It’s been a long haul, a big haul, but we’ve made it’: hepatitis C virus treatment in post-transplant patients with virus recurrence: An interpretative phenomenological analysis [PDF]

open access: yesHealth Psychology Open, 2018
The lived experience of both interferon-based and new interferon-free treatments in patients with hepatitis C virus remains understudied. To explore their journey through hepatitis C virus treatment, we interviewed seven post-transplant patients with ...
Anna Krzeczkowska   +4 more
doaj   +4 more sources

Human immunodeficiency virus and hepatitis C virus/hepatitis B virus co-infection in Southern Brazil: clinical and epidemiological evaluation [PDF]

open access: yesBrazilian Journal of Infectious Diseases, 2014
Hepatitis B virus, hepatitis C virus and human immunodeficiency virus share a similar transmission pathway and are often diagnosed in the same patient. These patients tend to have a faster progression of hepatic fibrosis.
Sonia Mara Raboni   +9 more
doaj   +3 more sources

Hepatitis C Virus [PDF]

open access: yesTrends in Microbiology, 2019
Hepatitis C virus (HCV) is an enveloped, RNA virus transmitted through blood-to-blood contact. It infects humans only and primarily targets liver cells. HCV evades innate and adaptive immunity and establishes chronic infections in 70% of cases. If untreated, 20% of patients develop liver cirrhosis, and a fraction of these progress to hepatocellular ...
Pietschmann, Thomas, Brown, Richard J P
openaire   +6 more sources

Hepatitis C virus [PDF]

open access: yesArchives of Virology, 1991
HepCV is the major cause of NANB PT hepatitis and is also implicated as the cause in a large proportion of sporadic cases of NANBH. Chronic infection with HepCV has also been linked to the development of hepatocellular carcinoma. Chimpanzees and marmosets are the only animals found to be experimentally infectable and the virus has not been propagated ...
Christine A. Lee, C Pereira, G Dusheiko
openaire   +6 more sources

Awareness and prevalence of hepatitis C virus infection among pregnant women in Nigeria: A national pilot cross-sectional study

open access: yesWomen's Health, 2021
Background: There are no national data on hepatitis C virus awareness and burden among pregnant women to justify its routine screening. Objectives: To investigate awareness, seroprevalence and risk factors for hepatitis C virus infection among pregnant ...
George Uchenna Eleje   +42 more
doaj   +1 more source

Recombination in Hepatitis C Virus [PDF]

open access: yesViruses, 2011
Hepatitis C virus (HCV) is a Flavivirus with a positive-sense, single-stranded RNA genome of about 9,600 nucleotides. It is a major cause of liver disease, infecting almost 200 million people all over the world. Similarly to most RNA viruses, HCV displays very high levels of genetic diversity which have been used to differentiate six major genotypes ...
Fernando González-Candelas   +2 more
openaire   +5 more sources

Near‐Infrared Optical Sensing of Biomacromolecules with Upconversion Nanoplatforms

open access: yesAdvanced Photonics Research, Volume 4, Issue 1, January 2023., 2023
In the past decades, continuous efforts have been dedicated to develop intelligent upconversion nanoplatforms (UCNs) for optical sensing of diverse biomacromolecules including DNA, RNA, proteins, and enzymes. Optical sensing and imaging have perceived massive success in biomedical analysis and disease diagnosis in terms of minimal invasiveness, good ...
Liben Yan, Zhimin Wang
wiley   +1 more source

Hepatitis C Virus and Hepatitis B Virus Co-Infection

open access: yesViruses, 2020
Hepatitis C virus (HCV) and hepatitis B virus (HBV) co-infection can be encountered in either virus endemic countries. Co-infection can also be found in populations at risk of parenteral transmission.
Yi-Fen Shih, Chun-Jen Liu
doaj   +1 more source

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