Results 11 to 20 of about 912,975 (349)
Archives of Virology, 1991 HepCV is the major cause of NANB PT hepatitis and is also implicated as the cause in a large proportion of sporadic cases of NANBH. Chronic infection with HepCV has also been linked to the development of hepatocellular carcinoma. Chimpanzees and marmosets are the only animals found to be experimentally infectable and the virus has not been propagated ...
Christine A. Lee, C Pereira, G Dusheiko
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Trends in Microbiology, 2019 Hepatitis C virus (HCV) is an enveloped, RNA virus transmitted through blood-to-blood contact. It infects humans only and primarily targets liver cells. HCV evades innate and adaptive immunity and establishes chronic infections in 70% of cases. If untreated, 20% of patients develop liver cirrhosis, and a fraction of these progress to hepatocellular ...
Pietschmann, Thomas, Brown, Richard J P
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Recombination in Hepatitis C Virus [PDF]
Viruses, 2011 Hepatitis C virus (HCV) is a Flavivirus with a positive-sense, single-stranded RNA genome of about 9,600 nucleotides. It is a major cause of liver disease, infecting almost 200 million people all over the world. Similarly to most RNA viruses, HCV displays very high levels of genetic diversity which have been used to differentiate six major genotypes ...
Fernando González-Candelas +2 more
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Hepatitis C virus and lymphoma [PDF]
Hepatology, 2016 Non ...
Ponzetto, Antonio, Carloni, Guido
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Hepatitis C virus infection [PDF]
Clinical Microbiology and Infection, 2005 Hepatitis C virus (HCV) infection is a major public health problem. Up to 3% of the world's population is infected with HCV, and at least 200 000 adults in the UK carry the virus. Of those exposed to HCV, 80% become chronically infected, and at least 30% of carriers develop chronic liver disease, including cirrhosis and hepatocellular carcinoma.
Roger Finch, B.J. Thomson
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Scientific Reports, 2017 The life cycle of hepatitis C virus (HCV) is highly dependent on host proteins for virus propagation. By transcriptome sequencing analysis, we identified host genes that were highly differentially expressed in HCV-infected cells.
Trang T. D. Luong +4 more
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Brazilian Journal of Infectious Diseases, 2015 Response-guided therapy is of limited use in developing countries because hepatitis C virus RNA detection by sensitive molecular methods is time- and labor-consuming and expensive.
Bo Feng +8 more
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AJPM Focus, 2023 Introduction: The purpose of this study was to characterize hepatitis C virus screening and treatment access experiences among people in treatment for opioid use disorder in Arizona during COVID-19.
Beth E. Meyerson, PhD +13 more
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Hepatitis C virus biology [PDF]
Cell Death & Differentiation, 2003 Hepatitis C virus infection represents a major problem of public health with around 350 millions of chronically infected individuals worldwide. The frequent evolution towards severe liver disease and cancer are the main features of HCV chronic infection.
GIANNINI, CARLO, Brechot C.
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An update on hepatitis C virus [PDF]
Clinical Medicine, 2015 Chronic hepatitis caused by hepatitis C virus infection is one of the leading causes of liver cirrhosis and hepatocellular carcinoma globally. Over the last few years, there have been significant advances in our understanding of the immunopathogenesis of this infection, as well as revolutionary developments in the therapeutic armamentarium.
Klenerman, P, Fitzmaurice, K
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