Results 51 to 60 of about 1,112,974 (279)
Status of Direct-Acting Antiviral Therapy for Hepatitis C Virus Infection and Remaining Challenges.
Gastroenterology, 2019 Chronic infection with hepatitis C virus is a major cause of liver disease and hepatocellular carcinoma worldwide. After the discovery of hepatitis C virus 3 decades ago, the identification of the structure of the viral proteins, combined with high ...
T. Baumert +3 more
semanticscholar +1 more source
, 2018 An estimated 185 million individuals have been infected with hepatitis C virus (HCV) worldwide. Although often clinically silent for decades, chronic HCV infection predisposes to late-onset complications, including liver cirrhosis and hepatocellular carcinoma.
openaire +1 more source
Brazilian Journal of Infectious Diseases, 2013 Objectives: Progression of hepatic fibrosis is accelerated in patients co-infected with human immunodeficiency virus and hepatitis C virus compared to hepatitis C virus mono-infected patients.
Denise Cerqueira Paranaguá Vezozzo +8 more
doaj +2 more sources
Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection
Science, 2010 Anti-MicroRNA Antiviral MicroRNAs (miRNAs) are small noncoding RNAs found in eukaryotes and viruses. They are critical regulators of a wide range of cellular processes.
R. Lanford +7 more
semanticscholar +1 more source
Hepatitis C virus core antigen assay: can we think beyond convention in resource limited settings?
Brazilian Journal of Infectious Diseases, 2013 Hepatitis C virus infects over 15 million patients from India and 2.86 million from Brazil. Detection of anti-hepatitis C virus antibodies has limited sensitivity during acute phase: the pre-seroconversion window period.
Anita Chakravarti +3 more
doaj +2 more sources
Bioinformatics Techniques used in Hepatitis C Virus Research
Journal of Pure and Applied Microbiology, 2017 Hepatitis C is widely spread and induces life threatening situations. Researchers from various fields have developed vaccine, but they are not that effective because of the variation in genotype of Hepatitis virus and also not much affordable.
Vikas Kaushik +2 more
doaj +1 more source
The context-specificity of virulence evolution revealed through evolutionary invasion analysis [PDF]
arXiv, 2023 Models are often employed to integrate knowledge about epidemics across scales and simulate disease dynamics. While these approaches have played a central role in studying the mechanics underlying epidemics, we lack ways to reliably predict how the relationship between virulence (the harm to hosts caused by an infection) and transmission will evolve in
arxiv
Journal of Infectious Diseases, 2018 Background Hepatitis C virus (HCV) exhibits great genetic diversity and is classified into 7 genotypes (GTs), with varied geographic prevalence. Until the recent development of pangenotypic direct-acting antiviral regimens, the determination of HCV GT ...
S. Borgia +10 more
semanticscholar +1 more source
SAGE Open MedicineObjective: Hepatitis B virus and hepatitis C virus are the leading causes of global liver-related morbidity and mortality. Waste handlers are one of the high-risk groups for hepatitis B virus and hepatitis C virus acquisition. Thus, the aim of this study
Alemu Gedefie +13 more
doaj +1 more source
Infection and Drug Resistance, 2022 Mitikie Wondmagegn,1 Yitayih Wondimeneh,2 Alem Getaneh,2 Getnet Ayalew2 1Department of Medical Laboratory Science, College of Medicine and Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia; 2Department of Medical Microbiology, School of ...
Wondmagegn M +3 more
doaj