Results 241 to 250 of about 149,243 (305)

Improving access to direct acting antivirals via a multimodal integrated care program in an addiction medicine clinic

open access: yesThe American Journal on Addictions, Volume 35, Issue 4, Page 534-542, July 2026.
Abstract Background and Objectives Injection drug use is a driver of hepatitis C virus (HCV) transmission, thus integrating HCV care into addiction care is likely necessary for HCV elimination. Here we describe how we integrated HCV care into our addiction medicine (AM) clinic and evaluate its effect on HCV treatment.
Arya Zandvakili   +11 more
wiley   +1 more source

Diagnostic Impact of Liver Biopsy Among Antinuclear Antibody Positive Individuals With Mild Liver Enzyme Elevation

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 1, Page 103-111, July 2026.
In ANA‐positive patients with suspected autoimmune hepatitis (AIH), liver biopsy rarely altered therapeutic management when alanine aminotransferase (ALT) was below 101 U/L and cirrhosis was absent. These findings suggest that biopsy may be safely deferred in this low‐risk group.
David Mehdi Asgher Niazi   +8 more
wiley   +1 more source

The T Cell Receptor: Molecular Sensor, Therapeutic Mediator and Probabilistic Driver of Adaptive Immunity

open access: yesImmunological Reviews, Volume 340, Issue 1, July 2026.
ABSTRACT Advances in high‐throughput sequencing, single‐cell profiling, and genome engineering have transformed the study of T cell receptors (TCRs), enabling the identification and functional interrogation of antigen‐specific repertoires at an unprecedented scale.
Kilian Schober
wiley   +1 more source

Assessing the Utility of Shortened Read Time of the Abbott Bioline HCV Test to Predict Viremia

open access: yesJournal of Viral Hepatitis, Volume 33, Issue 7, July 2026.
ABSTRACT The current two‐step model for HCV diagnosis risks losing people from care; a one‐step diagnostic approach could improve retention. We investigated whether shortening the read time of an HCV antibody test from 20‐min to 1 or 5‐min could accurately predict HCV RNA viremia in‐lieu of a standard RNA test.
Bridget Louise Draper   +6 more
wiley   +1 more source

Drug Use and Social Connectivity Related to Hepatitis C Infection Among Rural People Who Use Drugs

open access: yesJournal of Viral Hepatitis, Volume 33, Issue 7, July 2026.
ABSTRACT People who use drugs (PWUD) have a disproportionately elevated risk of hepatitis C virus (HCV). Appropriate screening and treatment may be limited, especially in rural environments experiencing healthcare shortages. In order to develop targeted intervention strategies for rural PWUD, we investigated individual and network‐level correlates of ...
Alex Rains   +6 more
wiley   +1 more source

Reframing Wnt/β‐Catenin Signalling in Liver Fibrosis: Transcriptional State Regulation by CBP and p300

open access: yesLiver International, Volume 46, Issue 7, July 2026.
ABSTRACT Liver fibrosis is a shared pathological phenotype of chronic liver diseases of diverse etiologies, including viral hepatitis, alcohol‐associated liver disease and metabolic dysfunction–associated steatohepatitis (MASH), as well as cholestatic liver diseases such as primary biliary cholangitis and primary sclerosing cholangitis, and may ...
Kiminori Kimura, Michinori Kohara
wiley   +1 more source

Burnt‐Out MASLD Predicts Outcomes After Curative Resection for Hepatocellular Carcinoma

open access: yesLiver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background and Aims Hepatic steatosis often diminishes as metabolic dysfunction–associated steatotic liver disease (MASLD) progresses, leading to a so‐called ‘burnt‐out’ state. Whether this phenotype simply reflects advanced liver injury or represents a biologically distinct condition with prognostic relevance after hepatocellular carcinoma ...
Yukihiro Watanabe   +10 more
wiley   +1 more source

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