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Hepatitis C virus (HCV) infection: A systemic disease
Molecular Aspects of Medicine, 2008Hepatitis C virus (HCV) infection is a global health problem, being the second most common chronic viral infection in the world with a global prevalence of about 3% (about 180 million people). HCV is both an hepatotropic and a lymphotropic virus; and chronic infection could cause, on one hand, chronic hepatitis, cirrhosis and hepatocellular carcinoma ...
Antonio Craxì +2 more
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Hepatitis C Virus (HCV) and Lymphomagenesis
Leukemia & Lymphoma, 2003Hepatitis C virus (HCV) is the major cause for non-A, non-B hepatitis. Most HCV-infected individuals do not clear the virus resulting in a chronic infection that may potentially lead to liver cirrhosis and hepatocellular carcinoma. In addition to hepatic manifestations, HCV infection is associated with B cell lymphoproliferative disorders, including ...
Wen-Kai, Weng, Shoshana, Levy
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Inhibitors Targeting Hepatitis C Virus (HCV) Entry
Mini-Reviews in Medicinal Chemistry, 2023Abstract: Infections caused by the Hepatitis C virus (HCV) affect around 70 million people worldwide, leading to serious liver problems, such as fibrosis, steatosis, and cirrhosis, in addition to progressing to hepatocellular carcinoma and becoming globally the main cause of liver disease.
Paulo Fernando da Silva Santos-Júnior +2 more
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Transplantation, 1995
Hepatitis C virus (HCV) genotypes, determined by polymerase chain reaction with type-specific primers, were studied in 5 already HCV-infected patients receiving kidneys from HCV-infected cadaver donors. Three patients were investigated retrospectively using stored pre- and posttransplantation sera and followed 18-28 months after transplantation.
A, Widell +5 more
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Hepatitis C virus (HCV) genotypes, determined by polymerase chain reaction with type-specific primers, were studied in 5 already HCV-infected patients receiving kidneys from HCV-infected cadaver donors. Three patients were investigated retrospectively using stored pre- and posttransplantation sera and followed 18-28 months after transplantation.
A, Widell +5 more
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Prevalence of antibodies to hepatitis C virus (HCV) in haemophiliacs
Blut, 1989The prevalence of 1) hepatitis C virus (HCV), an agent likely to be responsible for parenterally transmitted hepatitis non-A, non-B, 2) hepatitis B virus (HBV) and 3) human immunodeficiency virus (HIV) infection was studied in 211 patients with clotting disorders (78% of the patients had residual factor activities of less than or equal to 2%). Of these
W, Schramm +7 more
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New drugs for hepatitis C virus (HCV)
Best Practice & Research Clinical Gastroenterology, 2000Lack of efficacy and significant side effects have severely limited the use of interferon-alpha (IFN-alpha) as the standard therapy for non-A non-B hepatitis (NANBH) caused by hepatitis C virus (HCV) and alternative, improved therapies are urgently sought.
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Hepatitis C Virus (HCV): A Review of Immunological Aspects
International Reviews of Immunology, 2008The present manuscript represents an updated review on different aspects of immunology involved during hepatitis C virus infection in human beings. This includes a brief mention of HCV structure, presentation of viral components to host immune system, and ensuing immune response and immunopathogenesis occurring during HCV infection. The present article
M, Irshad +3 more
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Prevalence of hepatitis C virus (HCV) genotypes in Balochistan
Molecular Biology Reports, 2008A molecular study was conducted to investigate the prevalence of Hepatitis C virus genotypes in HCV infected population of Balochistan. Forty HCV seropositive samples belonging to seven different locations of Balochistan were collected from different health care centres.
Sarwat, Afridi +5 more
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Journal of Medical Virology, 1998
The quasispecies nature of hepatitis C virus (HCV) in patients with mixed HCV subtype infection was compared with that in patients with single HCV subtype infection. The number of HCV quasispecies was compared between 35 patients with mixed HCV subtype infection and 83 patients with single subtype infection.
H, Toyoda +9 more
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The quasispecies nature of hepatitis C virus (HCV) in patients with mixed HCV subtype infection was compared with that in patients with single HCV subtype infection. The number of HCV quasispecies was compared between 35 patients with mixed HCV subtype infection and 83 patients with single subtype infection.
H, Toyoda +9 more
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Hepatitis C virus (HCV) and autoimmune liver diseases
1992Anti-HCV tests were positive in 18-45% of sera from patients with autoimmune chronic active hepatitis. High gammaglobulin levels may result in false positive results, however, some sera show true positivity. PCR testing of such sera is necessary in order to determine whether HCV is directly involved in specific forms of the disease.
K H, Meyer zum Büschenfelde +2 more
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