Results 1 to 10 of about 19,226,899 (298)
Chronic hepatitis D associated with worse patient-reported outcomes than chronic hepatitis B [PDF]
JHEP Reports, 2021 Health-related quality of life (HRQoL) determined by patient-reported outcomes (PROs) is impaired in chronic hepatitis B (CHB) and C patients, but there are no data regarding patients with chronic hepatitis D (CHD). The aim of this study was to assess PRO scores in untreated patients with CHD and compare them with those obtained for patients with CHB ...
Stepanova, Maria +7 more
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Burden of Chronic Hepatitis D in Mongolia
Central Asian Journal of Medical Sciences, 2020 No abstract in ...
Sarantuya Gidaagaya +2 more
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Peripheral Biomarkers in Chronic Hepatitis D Infection: A Review. [PDF]
J Viral HepatABSTRACT Chronic hepatitis D represents the most severe form of viral hepatitis and is associated with higher rates of advanced fibrosis, cirrhosis and hepatocellular carcinoma than hepatitis B monoinfection. It is caused by the hepatitis D virus (HDV), a defective RNA virus that requires co‐infection with hepatitis B (HBV) for ...
Cargill Z, Lok J, Dusheiko G, Carey I.
europepmc +3 more sources
Interferon alpha for chronic hepatitis D [PDF]
Cochrane Database of Systematic Reviews, 2011 Hepatitis D virus is a small defective RNA virus that requires the presence of hepatitis B virus infection to infect a person. Hepatitis D is a difficult-to-treat infection. Several clinical trials have been published on the efficacy of interferon alpha for hepatitis D virus (HDV) infection.
Abbas, Zaigham +3 more
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Interferon‐based treatment of chronic hepatitis D
Liver International, 2022 AbstractTreatment of hepatitis D virus (HDV) infection has been based on the administration of interferon‐alfa for more than three decades. First studies to treat HDV‐infected patients with type 1 interferons were already performed in the 1980s. Several smaller trials and case series were reported thereafter.
Lisa Sandmann, Heiner Wedemeyer
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Entecavir Treatment of Chronic Hepatitis D
Clinical Infectious Diseases, 2012 Hepatitis D virus (HDV) requires hepatitis B surface antigen (HBsAg) to propagate infection and cause disease. Entecavir is a nucleoside analog with potent antiviral efficacy, and in the woodchuck animal model it also decreased hepatitis B virus (HBV) cccDNA and woodchuck surface antigen.
Kabacam, Gokhan +9 more
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An update on the management of chronic hepatitis D
Gastroenterology Report, 2019 Abstract Hepatitis D virus (HDV) infection is associated with severe liver-related morbidity and mortality. The prevalence of HDV is rising especially among people who abuse drugs and immigrants from endemic areas. Reliable diagnostic assays with enhanced sensitivity and specificity are essential for screening at-risk populations ...
Shah, Pir Ahmad +3 more
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Microbiology Spectrum, 2016 ABSTRACTChronic hepatitis B, C, and D virus infections contribute significantly to the morbidity and mortality of immunocompromised individuals. To contextualize discussion of these infections in immunocompromised patients, this paper provides an overview of aspects of infection in normal hosts.
Bryan R, Cobb, Alexandra, Valsamakis
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“Defective” mutations of hepatitis D viruses in chronic hepatitis D patients
World Journal of Gastroenterology, 2005 To verify whether "defective" mutations existed in hepatitis D virus (HDV).Hepatitis delta antigen (HDAg)-coding sequences were amplified using Pfu DNA polymerases with proof-reading activities from sera of five patients with chronic hepatitis D. Multiple colonies were sequenced for each patient. Pfu analyzed a total of 270 HDV clones.
Jaw-Ching, Wu +6 more
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Positive Selection of Hepatitis Delta Antigen in Chronic Hepatitis D Patients [PDF]
Journal of Virology, 2007 ABSTRACTLiver disease may become ameliorated in some patients with chronic hepatitis D virus (HDV) infection. We present here a study based on longitudinal sampling to investigate the viral dynamics in chronic HDV infection. We examined the HDV variants from different time points, especially those before and after the elevation of serum ...
Shen-Yung, Wang +5 more
openaire +2 more sources