Results 101 to 110 of about 19,226,899 (298)

Significance of Vitamin D Receptor Gene Polymorphisms for Risk of Hepatocellular Carcinoma in Chronic Hepatitis C

Translational Oncology, 2014
BACKGROUND/AIMS: Biological and epidemiological data suggest that vitamin D levels may influence cancer development. Several single nucleotide polymorphisms have been described in the vitamin D receptor (VDR) gene in association with cancer risk.
Chao-Hung Hung, Yi-Chun Chiu, Tsung-Hui Hu, Chien-Hung Chen, Sheng-Nan Lu, Chao-Min Huang, Jing-Houng Wang, Chuan-Mo Lee   +7 more
doaj   +1 more source

Viral adaptation to host immune responses occurs in chronic hepatitis B virus (HBV) infection, and adaptation is greatest in HBV e antigen-negative disease [PDF]

, 2012
Hepatitis B virus (HBV)-specific T-cell responses are important in the natural history of HBV infection. The number of known HBV-specific T-cell epitopes is limited, and it is not clear whether viral evolution occurs in chronic HBV infection. We aimed to
Chopra, A., Gordon, A, Scott Bowden, Pfafferott, K, Desmond, P.V., Ian R. James, Revill, P.A., Chopra, A, Mallal, SA, Silvana Gaudieri, Anna Ayres, Lewin, S.R., Thompson, AJ, Desmond, C.P., Jennifer Audsley, James, IR, Locarnini, SA, Stephen A. Locarnini, Sharon R. Lewin, James, I.R., Locarnini, S.A., Chivers, S., Christopher P. Desmond, Desmond, PV, Thompson, A.J., Stuart K. Roberts, Audsley, J, Revill, PA, Lau, GK, Gaudieri, S, Gaudieri, S., Audsley, J., Day, C, Caroline Day, Ayres, A, Day, C., Paul V. Desmond, Pfafferott, K., Gordon, A., Roberts, SK, Peter A. Revill, Alexander J. Thompson, Ayres, A., Desmond, CP, Sarah Chivers, Katja Pfafferott, Bowden, S., George K. Lau, Simon A. Mallal, Lewinb, SR, Lau, G.K., Roberts, S. K., Abha Chopra, Bowden, S, Mallal, S.A., Adam Gordon, Chivers, S   +56 more
core   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Prevalence of chronic viral hepatitis B, D among Mongol migrants in Sweden compared to a sex- and age-matched native Mongol cohort

BMC Infectious Diseases
Background & aims Chronic hepatitis B/D is the most severe form of chronic viral hepatitis, yet public awareness of its burden remains low. This study examined the prevalence of viral hepatitis B and D among Mongol migrants in Sweden and facilitated ...
Delgersaikhan Zulkhuu, Habiba Kamal, Sanjaasuren Enkhtaivan, Ochirmaa Narantsogt, Ganbolor Jargalsaikhan, Munguntsetseg Batkhuu, Byambasuren Ochirsum, Marcus Ahl, Karin Lindahl, Michael Ingre, Natalie Stiglund, Alexandros Petropoulos, Gustaf Sandh, Niklas K. Björkström, Sonja Saario, Susanne Cederberg, Annika Olsson, Anna Wange Baye, Ihssan Derdabi, Desideria Georgos, Andreas S. Bungert, Nara Bungert Dashdorj, N. D. Dashdorj Onom, Soo Aleman   +23 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Development of multiple myeloma in a patient with chronic hepatitis C: A case report and review of the literature [PDF]

, 2006
An association between chronic hepatitis C virus (HCV) infection and essential mixed cryoglobulinaemia and non-Hodgkin lymphoma (NHL) has been suggested. However, a causative role of HCV in these conditions has not been established.
Lakatos, Péter László, Horányi, Margit, Abonyi, Margit E., Fischer, Simon, Fekete, Sándor   +4 more
core   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Prevalence of HDV-RNA in HBV-DNA Positive Patients

Viral Hepatitis Journal, 2012
Objective:Hepatitis D virus (HDV) requires Hepatitis B virus(HBV) for replication and may cause to severe acute and chronic hepatitis. HDV is more frequently detected in our region In this study, HDV-RNA frequency was investigated in HBV-DNA-positive ...
Mustafa BERKTAŞ, Mehmet PARLAK, Aytekin ÇIKMAN, Metin YÜCE, Görkem YAMAN   +4 more
doaj   +1 more source

Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation [PDF]

, 2010
End-stage liver disease caused by chronic hepatitis C virus (HCV) infection is a leading cause for liver transplantation (LT). Due to viral evasion from host immune responses and the absence of preventive antiviral strategies, reinfection of the graft is
Pessaux, Patrick, Doffoel, Michel, Leroux-Roels, G., Stoll-Keller, Françoise, Michel Doffoël, Patel, Arvind H, Samira Fafi-Kremer, Fofana, I., Soulier, E., Patric Carolla, Fafi-Kremer, S., Doffoel, M., Stoll-Keller, F., Cosset, F.-L., Meuleman, Philip, Fafi-Kremer, Samira, Eric Soulier, Philip Meuleman, Isabel Fofana, Wolf, P., Soulier, Eric, Cosset, François-Loic, François-Loïc Cosset, Leroux-Roels, Geert, Wolf, Philippe, Françoise Stoll-Keller, Philippe Wolf, Carolla, Patric, Pessaux, P., Meuleman, P., Baumert, Thomas F, Patel, A.H., Fofana, Isabel, Patrick Pessaux, Thomas F. Baumert, Arvind H. Patel, Geert Leroux-Roels, Carolla, P., Baumert, T.F.   +38 more
core   +1 more source