Results 21 to 30 of about 369,907 (149)
Quantitative Serum HBsAg and M2BPGi Levels in Patients with Chronic Hepatitis D
Central Asian Journal of Medical Sciences, 2016 Objectives: Quantification of serum HBsAg has several clinical significances such as acting as a biomarker for the hepatitis D virus (HDV)-RNA level and necroinflammatory activity in HDV infection.
Sarantuya Gidaagaya +6 more
doaj +1 more source
Virologic Tools for HCV Drug Resistance Testing
Viruses, 2015 Recent advances in molecular biology have led to the development of new antiviral drugs that target specific steps of the Hepatitis C Virus (HCV) lifecycle. These drugs, collectively termed direct-acting antivirals (DAAs), include non-structural (NS) HCV
Slim Fourati, Jean-Michel Pawlotsky
doaj +1 more source
Pharmacotherapy of hepatitis D: the current and the future [PDF]
Exploration of Digestive DiseasesHepatitis D virus (HDV), a satellite virus requiring hepatitis B surface antigen (HBsAg) for propagation, is a hepatotropic virus implicated in acute and chronic viral hepatitis, with an accentuated risk of cirrhosis and hepatocellular carcinoma.
George Sarin Zacharia, Anu Jacob
doaj +1 more source
Identification of Novel HBV/HDV Entry Inhibitors by Pharmacophore- and QSAR-Guided Virtual Screening
Viruses, 2021 The hepatic bile acid transporter Na+/taurocholate co-transporting polypeptide (NTCP) was identified in 2012 as the high-affinity hepatic receptor for the hepatitis B and D viruses (HBV/HDV).
Michael Kirstgen +10 more
doaj +1 more source
VITAMIN D LEVELS IN PATIENTS WITH CHRONIC HEPATITIS B, CHRONIC HEPATITIS C, AND HEALTH CONTROLS [PDF]
Journal of IMAB, 2019 Purpose: Hepatitis B virus and Hepatitis C virus infection are the most common cause of acute and chronic hepatitis. Over the past decade, numerous studies reported that patients with chronic liver disease, especially HCV-positive and HBV-positive ...
Biljana Ilkovska +3 more
doaj +1 more source
Modern aspects of anti-viral therapy for hepatitis D
Журнал инфектологииViral hepatitis D (HDV infection) worsens the prognosis of HBV infection course in 80-90% of cases, accelerating fibrosis and leading to liver cirrhosis or hepatocellular carcinoma. Hepatitis D affects at least 125 000 people in Russia, and in the world,
A. S. Zheleznova +2 more
doaj +1 more source
Comparative analysis of vitamin D contents in patients with chronic viral hepatitis C and healthy.
Medičnì Perspektivi, 2020 From scientific literature it is known that vitamin D helps maintain the most important functions of the immune system, there is evidence of its role in inflammatory and metabolic diseases of the liver, including infection with hepatitis C.
L. L. Shostakovych-Koretskaya +5 more
doaj +3 more sources
Вестник трансплантологии и искусственных органовChronic hepatitis B virus (HBV) infection is one of the main problems of modern transplantology and transplant hepatology, often leading to potentially fatal complications. The only definitive treatment for HBV-related cirrhosis is liver transplantation.
U. R. Salimov +5 more
doaj +1 more source
Family foci of HDV infection in the Republic of Sakha (Yakutia)
Журнал инфектологииThis study is devoted to the analysis of the epidemiological situation of chronic hepatitis D in Yakutia, as a region where chronic viral hepatitis is widespread.Aim: To characterize family foci of chronic hepatitis D in the Republic of Sakha (Yakutia ...
O. M. Zamorshchikova +2 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source