Results 31 to 40 of about 369,907 (149)

Prevalence of Viral Hepatitis B, C, and D in Kazakhstan

open access: yesThe Scientific World Journal, 2022
Background. Viral hepatitis is a major burden for the healthcare system worldwide. Up to date, a comprehensive analysis of the prevalence of viral hepatitis in Kazakhstan and Central Asia has not been carried out yet.
Almagul Jumabayeva   +7 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Tyrosine 146 of the Human Na+/Taurocholate Cotransporting Polypeptide (NTCP) Is Essential for Its Hepatitis B Virus (HBV) Receptor Function and HBV Entry into Hepatocytes

open access: yesViruses, 2022
Na+/taurocholate cotransporting polypeptide (NTCP, gene symbol SLC10A1) is a hepatic bile acid uptake carrier participating in the enterohepatic circulation of bile acids. Apart from its transporter function, NTCP acts as the high-affinity liver-specific
Dariusz Zakrzewicz   +9 more
doaj   +1 more source

Prevalence of hepatitis D virus infection in sub-Saharan Africa: a systematic review and meta-analysis

open access: yesThe Lancet Global Health, 2017
Background: Hepatitis D virus (also known as hepatitis delta virus) can establish a persistent infection in people with chronic hepatitis B, leading to accelerated progression of liver disease. In sub-Saharan Africa, where HBsAg prevalence is higher than
Alexander J Stockdale, MRes   +8 more
doaj   +1 more source

Chronic Hepatitis B and Related Liver Diseases Are Associated with Reduced 25-Hydroxy-Vitamin D Levels: A Systematic Review and Meta-Analysis

open access: yesBiomedicines, 2023
Hepatitis B infection is a major public health problem globally leading to chronic liver disease and death, which are influenced by various environmental and host factors including serum 25-hydroxy-vitamin D levels.
Anindita Banerjee   +4 more
doaj   +1 more source

Atypical crusted scabies in a patient with chronic liver disease caused by hepatitis B and D viruses [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2018
: Crusted scabies is a less common variant of scabies that is highly contagious, difficult to treat and involves infestation by Sarcoptes scabiei var. hominis. The classical clinical presentation includes crusted, scaly and generally non-pruritic lesions
Mônica Santos   +3 more
doaj   +1 more source

Hepatitis B prevalence, knowledge and attitudes among health-care workers and antenatal mothers attending a tertiary hospital in South Tarawa, Kiribati: insights from a 2022 cross-sectional study

open access: yesWestern Pacific Surveillance and Response
Objective: Hepatitis B virus infection is hyperendemic in Kiribati (~15% prevalence rate), with vaccination and antiviral treatment being the mainstays of control.
Thomas Russell, Vikash Sharma, Alice Lee
doaj   +1 more source

Comparative analysis of vitamin D contents in patients with chronic viral hepatitis C and healthy.

open access: yesMedičnì Perspektivi, 2019
From scientific literature it is known that vitamin D helps maintain the most important functions of the immune system, there is evidence of its role in inflammatory and metabolic diseases of the liver, including infection with hepatitis C.
L. L. Shostakovych-Koretskaya   +5 more
doaj   +1 more source

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