Results 91 to 100 of about 1,000,209 (254)
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng +20 more
wiley +1 more source
Skin Cancers in Australian Liver Transplant Recipients: Risk Factors and Histology
ABSTRACT Background Skin cancer is one of the most common comorbidities for liver transplant recipients (LTRs). Carcinogenesis is a multifaceted process: immunosuppression and personal risk factors such as smoking status, UV exposure, past history of skin cancer and family history of skin cancer can all play a significant role in determining the extent
Rohan Rajaram +7 more
wiley +1 more source
РАЗВИТИЕ ГЕПАТОЦЕЛЛЮЛЯРНОЙ КАРЦИНОМЫ В ИСХОДЕ ХРОНИЧЕСКОЙ ДЕЛЬТА-ИНФЕКЦИИ
Hepatocellular carcinoma is 95% of the total malignant liver tumors. Total 318 patients with chronic delta infection, indigenous inhabitants of the Republic of Tyva, were examined. 121 patients were observed in dynamic (2009–2012).
Л. Ю. Ильченко +6 more
doaj +1 more source
Optimizing Prolonged (6 h) Normothermic Machine Perfusion of Donor Kidneys (PROPER Study)
Prolonged ex situ normothermic machine perfusion of donor kidneys up to 6 h is feasible, maintaining viability and histological integrity. Key protocol optimizations include fresh red blood cells, albumin supplementation, and urine recirculation—laying the groundwork for assessment and potential pretransplant interventions in future clinical trials ...
Asel S. Arykbaeva +14 more
wiley +1 more source
Immunological response of Hepatitis B Virus Surface Antigen in HBV Mono and HBV/HDV Co-infection
Hepatitis B virus (HBV) can evolve under selection pressure exerted by drugs and host immunity, resulting in the accumulation of escape mutations that can affect the drug or the immune activity.
Mehwish Sajjad +3 more
doaj +1 more source
Nationwide implementation of double reflex testing for hepatitis delta in Spain markedly increased anti‐HDV and HDV viral load testing between 2022 and 2024, enabling national seroprevalence estimates. Despite this progress, substantial regional heterogeneity persists, highlighting the need for standardised reflex diagnostic protocols.
Ana Alberola +95 more
wiley +1 more source
Autoantibodies in hepatitis delta
Hepatitis delta virus infection is associated with a wide range of different autoantibodies. The humoral immune response in chronic hepatitis D is directed against the cytoskeleton, the nucleus, the nuclear lamina and the endoplasmic reticulum. Smooth muscle antibodies (SMA), basal cell layer antibodies (BCLA), stellate epithelial cell antibodies (SECA)
T, Philipp +2 more
openaire +2 more sources
We used an administrative claims dataset to evaluate the relationship between hepatitis B virus (HBV) low‐level viraemia and subsequent liver‐related outcomes in patients with chronic HBV. We found that individuals with HBV low‐level viraemia have an increased risk for liver‐related events (i.e., cirrhosis, decompensation, and hepatocellular carcinoma)
Paul Y. Kwo +11 more
wiley +1 more source
Hepatitis B virus (HBV) infections remain a significant global health challenge, especially in low- and middle-income countries where access to healthcare services is often limited.
Antoanela Curici +2 more
doaj +1 more source
Epidemiological features Delta together multiple infection in Saint-Petersburg
Studied the epidemiological features of the delta as a coinfection of hepatitis B in Saint-Petersburg for 14-year period (2002–2014). Clinical and laboratory data of 232 patients admitted to Botkin CIB them during this period.
V. V. Nechaev +9 more
doaj +1 more source

