Results 141 to 150 of about 691,238 (259)
When to consider an inborn error of immunity: clues for physicians
Internal Medicine Journal, Volume 56, Issue 9, Page 1488-1499, September 2026.Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley +1 more source
Hepatitis C : by the numbers [PDF]
Hepatitis C is among the deadliest infectious diseases in the United States. In 2019, approximately 14,242 death certificates listed hepatitis C as an underlying or contributing cause of death in the United States and the number of people newly infected ...
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Immunology, Volume 179, Issue 1, Page 138-148, September 2026.This study investigates the impact of switching to long‐acting (LA) injectable cabotegravir and rilpivirine (CAB/RPV‐LA) on immune‐activation and ‐senescence in people with HIV (PWH). Thirty‐seven PWH switching to CAB/RPV‐LA and nine continuing oral ART were analysed over 72 weeks. LA therapy led to significant reductions in activation T and senescence
Mariasilvia Guardiani +16 more
wiley +1 more source
Treatment Goals for Primary Biliary Cholangitis, an Australian Perspective
Journal of Gastroenterology and Hepatology, Volume 41, Issue 9, Page 2623-2638, September 2026.ABSTRACT Primary biliary cholangitis (PBC) is an autoimmune liver disease that targets the small intrahepatic bile ducts with diagnosis based on elevated serum alkaline phosphatase (ALP) levels and the presence of anti‐mitochondrial antibodies. Untreated, it may run a progressive course to cirrhosis and hepatic decompensation, at which point liver ...
Simone I. Strasser +6 more
wiley +1 more source
Revista Española de Enfermedades Digestivas, 2007 Romero-Portales, M. +1 more
openaire +4 more sources
Enhancing CRISPR‐Cas12a base editing in plants with LbCas12a variants and introns
Journal of Integrative Plant Biology, Volume 68, Issue 9, Page 3243-3259, September 2026.Intron optimization of LbCas12a‐RRV improves cytosine and adenine base editing efficiency in plants, supports multiplexed and double‐strand break‐free genome modification, and expands precise genome engineering tools for crop breeding and plant functional research. ABSTRACT Cytosine base editors (CBEs) and adenine base editors (ABEs) are powerful tools
Yanhao Cheng +5 more
wiley +1 more source
Journal of Viral Hepatitis, Volume 33, Issue 9, September 2026.ABSTRACT To close gaps in implementing care of people with hepatitis B virus (HBV) infection in resource‐limited settings, we evaluated the accuracy of a novel liver point‐of‐care ultrasound (POCUS) protocol for hepatitis (PUSH) among front‐line non‐radiology healthcare workers in Zambia. At University Teaching Hospital in Lusaka, Zambia, from March to
Costanza Bertoni +15 more
wiley +1 more source
Delta High School; class of 1935
, 1955 Our Class reunion, 1955, celebrating our first get together in twenty years: First row: Pearl Steele Hawley, Mary Daly Warnick, Hazel Lovell Walker, Nina Millett Nichols, Phyllis Wright Wood, Roe Ann Sampson Gooch, Pearl Warnick Nelson, Ruby Allen Bishop.
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ChemMedChem, Volume 21, Issue 16, 27 August 2026.Ligand‐based virtual screening of over five million compounds identifies a thienopyrimidinone hit as a novel allosteric nSMase2 modulator. Structure‐guided optimisation improves inhibitory potency and delivers derivatives with antiviral activity against West Nile virus, expanding the chemical space of nSMase2 inhibitors and supporting host‐directed ...
Hadrián Álvarez‐Fernández +6 more
wiley +1 more source