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Heterogeneity of hepatitis delta antigen

Virology, 1990
Hepatitis delta antigen (HDAg) is the only known protein encoded by the hepatitis delta virus (HDV). Two HDAg species of different sizes have been detected in the sera and livers of the infected humans, chimpanzees, and woodchucks, even though only one RNA species was previously identified in most of the HDV strains.
Y P, Xia   +4 more
openaire   +2 more sources

Acute Delta Hepatitis and Hepatitis B Antigen Carriage

Annals of Internal Medicine, 1986
Excerpt To the editor: In the July issue, De Cock and colleagues (1) described the clinical course of acute delta hepatitis superimposed in 38 persons who were carriers of hepatitis B surface antig...
N C, Tassopoulos   +2 more
openaire   +2 more sources

The roles of the delta antigen in the structure and replication of hepatitis delta virus

Journal of Hepatology, 1991
The delta antigen is the only known protein encoded by hepatitis delta virus (HDV). The predicted protein is 195 amino acids in length, but for reasons that are not yet clear, there occurs during the replication of the HDV genome, a specific base change in the termination codon of this open reading frame.
J, Taylor, M, Chao, S Y, Hsieh, W S, Ryu
openaire   +2 more sources

Hepatitis delta antigen. Antigenic structure and humoral immune response.

The Journal of Immunology, 1989
Abstract Hepatitis delta virus (HDV) is a small RNA virus that is dependent on helper functions provided by hepatitis B virus. The hepatitis delta Ag (HDAg) is the only protein known to be made from the viral genome, from an ORF with a coding capacity of 214 amino acids.
K F, Bergmann   +3 more
openaire   +2 more sources

Delta-Interacting Protein A and the Origin of Hepatitis Delta Antigen

Science, 1997
Robert Brazas and Don Ganem ([1][1]) propose that the cellular protein, delta-interacting protein A (DIPA), interacts with hepatitis delta antigen (HDAg), affecting hepatitis delta virus (HDV) replication.
Manyuan Long   +2 more
openaire   +1 more source

Hepatitis Delta Antigen

2007
Hepatitis delta antigen (HDAg) was first detected in the nucleus of the hepatocytes of some patients infected with hepatitis B virus (HBV).68 The presence of HDAg was frequently associated with severe hepatitis. This antigen was initially thought to be a previously unrecognized HBV-encoded antigen, but later was found to be associated with a novel ...
openaire   +1 more source

Immune response to synthetic peptides of hepatitis delta antigen

Journal of Clinical Microbiology, 1993
Hepatitis delta antigen (HDAg) is the only viral protein known to be expressed during hepatitis delta virus (HDV) infection. Detection of antibody to HDAg (anti-HD) is the usual method for diagnosis of HDV infection since viremia lasts only a few weeks.
F, Poisson   +5 more
openaire   +2 more sources

[Delta-antigen in hepatitis B].

Schweizerische medizinische Wochenschrift, 1982
Among 571 liver biopsies delta-Ag was found in 10 of 365 HBsAg positive patients (9 with CAH, 1 with CPH). Delta-Ag was demonstrated in nuclei and cytoplasm of liver cells in both cryostat and paraffin sections. Follow-up studies revealed persistence of delta-Ag for as long as 6 years and temporary appearance or loss of Dane particle-associated ...
E, Stöcklin   +4 more
openaire   +1 more source

Hepatitis Delta Antigen and RNA Polymerase II

2007
Replication and transcription of HDV proceed via RNA-dependent RNA synthesis. These reactions are thought to be catalyzed at least in part by host RNA polymerase II (RNAPII). Hepatitis delta antigen (HDAg), which is critical for these processes, was recently proposed to function as a transcription elongation factor for RNAPII.
Yuki Yamaguchi, Hiroski Handa
openaire   +1 more source

Functional studies of hepatitis delta antigen and delta virus RNA.

Progress in clinical and biological research, 1991
We have sequenced an HDV RNA from an acute delta hepatitis patient from the Nauru Islands. By comparison with other HDV sequences previously reported, we have identified three conserved regions: the first one is the sequence around the catalytic cleavage site for genomic-sense RNA; the second is the corresponding site for the antigenomic sense RNA; and
M M, Lai   +4 more
openaire   +1 more source

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