Association of the pri-miR-34b/c rs4938723 T > C polymorphism with hepatoblastoma susceptibility in Eastern Chinese children: A five-center case-control study [PDF]
BMC Medical GenomicsBackground Hepatoblastoma is the most prevalent liver cancer affecting children, and its intricate causes are closely linked to genetic variations. This study interrogated the influence of the miR-34b/c rs4938723 T > C polymorphism in hepatoblastoma ...
Wenli Zhang +8 more
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From preneoplastic lesion to heterogenous tumor: recent insights into hepatoblastoma biology and therapeutic opportunities [PDF]
Molecular CancerHepatoblastoma is the most common pediatric liver cancer, with the fastest rising incidence among childhood malignancies. Early genomic studies revealed that hepatoblastoma has the lowest mutational burden of any human cancer, however, recent advances in
Jun Yang +2 more
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Recent updates on the classification of hepatoblastoma according to the international pediatric liver tumors consensus [PDF]
Journal of Liver Cancer, 2022 Hepatoblastoma is the most common pediatric liver malignancy and usually occurs within the first 3 years of life. In recent years, the overall incidence of hepatoblastoma has exhibited the greatest increase among all pediatric malignancies worldwide. The
Se Un Jeong, Hyo Jeong Kang
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The Genetic Changes of Hepatoblastoma
Frontiers in Oncology, 2021 Hepatoblastoma is the most common malignant liver cancer in childhood. The etiology of hepatoblastoma remains obscure. Hepatoblastoma is closely related to genetic syndromes, hinting that hepatoblastoma is a genetic predisposition disease.
Huitong Chen +6 more
doaj +1 more source
Epigenetics and genetics of hepatoblastoma: Linkage and treatment
Frontiers in Genetics, 2022 Hepatoblastoma is a malignant embryonal tumor with multiple differentiation modes and is the clearest liver malignancy in children. However, little is known about genetic and epigenetic events in Hepatoblastoma.
Li-ran Zhu +9 more
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Nature Communications, 2023 A lack of relevant genetic models and cell lines hampers our understanding of hepatoblastoma pathogenesis and the development of new therapies for this neoplasm.
Jie Fang +28 more
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A population-based assessment of metastatic hepatoblastoma in Texas reveals ethnic disparities
Frontiers in Public Health, 2023 BackgroundHepatoblastoma (HB) is the most common primary liver cancer in children with emerging evidence that incidence is increasing globally. While overall survival for low risk hepatoblastoma is >90%, children with metastatic disease have worse ...
Andres F. Espinoza +4 more
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Total hepatectomy and liver transplant for hepatocellular adenomatosis and focal nodular hyperplasia. [PDF]
, 1992 Extensive hepatocellular adenomatosis (HA) and focal nodular hyperplasia (FNH) represent a proliferation of hepatic cells that occurs most frequently in women.
Bronsther, O +4 more
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Revista Española de Enfermedades Digestivas, 2013 Adult hepatoblastoma (AHB) is a very rare tumor, having been described 45 cases up to June 2012. In contrast to HB in infancy (IHB), it has poor prognosis. We present the case of a 37-year-old asymptomatic woman who consulted for a large -12 cm diameter- mass involving segments 5 and 6 of the liver, and alfa-fetoprotein of 1,556,30 UI/mL.
Cienfuegos,Javier A. +6 more
openaire +3 more sources
Genome-wide analysis of long noncoding RNA (lncRNA) expression in hepatoblastoma tissues. [PDF]
PLoS ONE, 2014 Long noncoding RNAs (lncRNAs) have crucial roles in cancer biology. We performed a genome-wide analysis of lncRNA expression in hepatoblastoma tissues to identify novel targets for further study of hepatoblastoma.
Rui Dong +7 more
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