Results 21 to 30 of about 21,170 (204)
METTL1 gene polymorphisms synergistically confer hepatoblastoma susceptibility
Discover Oncology, 2022 Introduction Hepatoblastoma is a rare but devastating pediatric liver malignancy. Overexpressed methyltransferase-like 1 (METTL1) is a methyltransferase that catalyzes essential N7-methylguanosine (m7G) modification of eukaryotic mRNA.
Lili Ge +10 more
doaj +1 more source
Progress and Comment on Surgical Treatment of Hepatoblastoma in Children
Zhongliu Fangzhi Yanjiu, 2022 Hepatoblastoma is the most common malignant tumor of liver in childhood. The onset of hepatoblastoma is insidious and the early symptoms are not typical. It is usually found in physical examination, mainly in the right lobe, and can involve several liver
ZHAN Jianghua, WANG Zhiru
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Expression Profiling Identifies Circular RNA Signature in Hepatoblastoma
Cellular Physiology and Biochemistry, 2018 Background/Aims: Hepatoblastoma is the most common malignant pediatric liver cancer. circular RNAs (circRNAs) play important roles in fine-tuning gene expression and are often deregulated in cancers.
Bai-Hui Liu +5 more
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Embryonal/Fetal Subtype Hepatoblastoma: A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2014 Hepatoblastoma is the most common primary liver tumor of childhood and after neuroblastoma and nephroblastoma the third most common abdominal neoplasm in this age group.
I Spyridakis +4 more
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Targeting PIM Kinases Affects Maintenance of CD133 Tumor Cell Population in Hepatoblastoma
Translational Oncology, 2019 Hepatoblastoma is the most common primary liver tumor in children, but treatment has not changed significantly in the past 20 years. We have previously demonstrated that Proviral Integration site for Moloney murine leukemia (PIM) kinases promote ...
Laura L. Stafman +7 more
doaj +1 more source
Focal adhesion kinase: Insight into molecular roles and functions in hepatocellular carcinoma [PDF]
, 2017 Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. Due to the high incidence of post-operative recurrence after current treatments, the identification of new and more effective drugs is required.
Alisi, Anna +4 more
core +2 more sources
Prognostic roles of pathology markers immunoexpression and clinical parameters in Hepatoblastoma
Journal of Biomedical Science, 2017 Background Hepatoblastoma, a leading primary hepatic malignant tumor in children, is originated from primitive hepatic stem cells. We aimed to elucidate the relationships between the histological distribution of β-catenin and hepatic stem cell markers ...
Jia-Feng Wu +6 more
doaj +1 more source
BMC Cancer, 2021 Background This study aimed to probe and verify aberrantly methylated and expressed genes in hepatoblastoma and to analyze their interactions with tumor immune microenvironment.
Yanbing Zhang +3 more
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Genetic and Modifiable Risk Factors Contributing to Cisplatin-Induced Toxicities [PDF]
, 2019 Effective administration of traditional cytotoxic chemotherapy is often limited by off-target toxicities. This clinical dilemma is epitomized by cisplatin, a platinating agent that has potent antineoplastic activity due to its affinity for DNA and other ...
Dinh, Paul C. Jr. +4 more
core +1 more source
Early experience in pediatric hepatic resection at IOM, TUTH
Journal of Society of Surgeons of Nepal, 2016 Total 5 pediatric hepatectomy were performed at IOM TUTH during last 2 years. Three children were cases of hepatoblastoma and two were cases of symptomatic focal noduler hyperplasia (FNH).
S Shah, P Kansakar, P Vaidya
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