Results 1 to 10 of about 25,003 (247)

Chemical and Pharmacological Aspects of Caffeic Acid and Its Activity in Hepatocarcinoma

Frontiers in Oncology, 2019
Caffeic acid (CA) is a phenolic compound synthesized by all plant species and is present in foods such as coffee, wine, tea, and popular medicines such as propolis.
Kaio Murilo Monteiro Espíndola, Roseane Guimarães Ferreira, Luis Eduardo Mosquera Narvaez, Amanda Caroline Rocha Silva Rosario, Agnes Hanna Machado da Silva, Ana Gabrielle Bispo Silva, Ana Paula Oliveira Vieira, Marta Chagas Monteiro   +7 more
doaj   +2 more sources

Epigenetic repression of de novo cysteine synthetases induces intra-cellular accumulation of cysteine in hepatocarcinoma by up-regulating the cystine uptake transporter xCT [PDF]

Cancer & Metabolism
Background The metabolic reprogramming of amino acids is critical for cancer cell growth and survival. Notably, intracellular accumulation of cysteine is often observed in various cancers, suggesting its potential role in alleviating the oxidative stress
Tomoaki Yamauchi, Yumi Okano, Daishu Terada, Sai Yasukochi, Akito Tsuruta, Yuya Tsurudome, Kentaro Ushijima, Naoya Matsunaga, Satoru Koyanagi, Shigehiro Ohdo   +9 more
doaj   +2 more sources

33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways

Journal of Advanced Research, 2021
Introduction: As a member of annexin family proteins, annexin A3 (ANXA3) has 36-kDa and 33-kDa isoforms. ANXA3 plays crucial roles in the tumorigenesis, aggressiveness and drug-resistance of cancers.
Chunmei Guo, Nannan Li, Chengyong Dong, Liming Wang, Zhaopeng Li, Qinlong Liu, Qinglai Ma, Frederick T. Greenaway, Yuxiang Tian, Lihong Hao, Shuqing Liu, Ming-Zhong Sun   +11 more
doaj   +1 more source

Antioxidant properties and cytotoxic effects of Oxalis corniculata on human Hepatocarcinoma (Hep-G2) cell line: an in vitro and in silico evaluation

Future Journal of Pharmaceutical Sciences, 2023
Oxalis corniculata is a well-known medicinal plant used in folk medicine for the management of many diseases. The aim is to determine the physico-chemical properties, microscopic study, phytochemical properties, in-silico, in-vitro antioxidant and ...
Sachin Gudasi, Shankar Gharge, R. Koli, K. Patil   +3 more
semanticscholar   +1 more source

Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma

Frontiers in Oncology, 2022
Purpose Recently, long noncoding RNA LINC01134 has been shown to reduce cell viability and apoptosis via the antioxidant stress pathway, thereby enhancing OXA resistance in hepatocellular carcinoma.
Xiaofeng Kang, Y. Huo, Songhao Jia, F. He, Huizi Li, Qing Zhou, Nijia Chang, Donghui Liu, Rong-kuan Li, Yingping Hu, Ping Zhang, An Xu   +11 more
semanticscholar   +1 more source

Late Recurrence of Hepatocellular Carcinoma in a Patient 10 Years after Liver Transplantation Unrelated to Transplanted Organ

Case Reports in Oncology, 2021
Liver transplantation (LTx) is an accepted method of hepatocellular carcinoma (HCC) treatment in cirrhotic patients; however, it has many limitations, and there is a substantial risk of recurrence.
Kornelia Morisson-Sarapak, Maciej Wrzesiński, Samir Zeair, Marta Wawrzynowicz-Syczewska   +3 more
doaj   +1 more source

Cirrhosis of the liver and hepatocellular carcinoma in the outcome of chronic hepatitis C: a case report

Лечащий Врач, 2023
The article presents a clinical case of cirrhosis of the liver of class C according to Child – Pugh in the outcome of chronic hepatitis C and with the development of primary liver cancer.
V. V. Makashova, Kh. G. Omarova, Zh. B. Ponezheva, O. S. Astrina, V. V. Breder, I. V. Pogrebnyakov, I. A. Dzhanyan, S. A. Magomedova   +7 more
doaj   +1 more source

Endoplasmic Reticulum Stress Signaling and the Pathogenesis of Hepatocarcinoma

International Journal of Molecular Sciences, 2021
Hepatocellular carcinoma (HCC), also known as hepatoma, is a primary malignancy of the liver and the third leading cause of cancer mortality globally. Although much attention has focused on HCC, its pathogenesis remains largely obscure.
Juncheng Wei, Deyu Fang
semanticscholar   +1 more source

An Automated Method for Classifying Liver Lesions in Contrast-Enhanced Ultrasound Imaging Based on Deep Learning Algorithms

Diagnostics, 2023
Background: Contrast-enhanced ultrasound (CEUS) is an important imaging modality in the diagnosis of liver tumors. By using contrast agent, a more detailed image is obtained.
Mădălin Mămuleanu, Cristiana Marinela Urhuț, Larisa Daniela Săndulescu, Constantin Kamal, Ana-Maria Pătrașcu, Alin Gabriel Ionescu, Mircea-Sebastian Șerbănescu, Costin Teodor Streba   +7 more
doaj   +1 more source

YRDC Mediates the Resistance of Lenvatinib in Hepatocarcinoma Cells via Modulating the Translation of KRAS

Frontiers in Pharmacology, 2021
Lenvatinib is the latest and promising agent that has demonstrated a significant improvement of progression-free survival in advanced hepatocellular carcinoma (HCC). However, resistance emerges soon after initial treatment, limiting the clinical benefits
Jun Guo, Peng Zhu, Z. Ye, Mengke Wang, Haijun Yang, Shiqiong Huang, Yan Shu, Wei Zhang, Honghao Zhou, Qing Li   +9 more
semanticscholar   +1 more source