Results 111 to 120 of about 25,003 (247)

TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation

Cell Death and Disease, 2018
Tripartite motif-containing 50 (TRIM50) belongs to the tripartite motif (TRIM) protein family, which has been implicated in the pathogenesis of multiple cancers. However, the role of TRIM50 in hepatocellular carcinoma (HCC) remains to be clarified.
Xiaoxiao Ma, Xiaomin Ma, Yumin Qiu, Lihui Zhu, Yueke Lin, Yajing You, D. Ma, Zhenzhi Qin, Caiyu Sun, Yunxue Zhao, Yanlin Sun, Lihui Han   +11 more
semanticscholar   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Combinación poco habitual de hepatocarcinoma con síndrome de Sjögren

Revista Cubana de Medicina Militar, 2018
El síndrome de Sjögren es una enfermedad reumática que aumenta el riesgo de padecer enfermedades malignas. Dentro de estas se identifican a los linfomas como las que con mayor frecuencia se presentan.
Urbano Solís Cartas, Yosniel Benítez Calero, Silvia Johana Calvopiña Bejarano, Gladys Lorena Aguirre Saimeda, Arelys de Armas Hernández   +4 more
doaj  

Autosomal Dominant Erythrocytosis Caused by Non‐Renal Erythropoietin (EPO) Due to EPO c.‐136 G>A Germline Mutation

American Journal of Hematology, Volume 101, Issue 4, Page 784-793, April 2026.
A novel erythropoietin (EPO) promoter mutation (c.‐136 G>A) causes autosomal dominant erythrocytosis via non‐renal expression of EPO. ABSTRACT We previously reported a five‐generation kindred with autosomal dominant erythrocytosis associated with a novel germline promoter variant in the erythropoietin (EPO) gene (EPO c.‐136 G>A).
Lucie Lanikova, Dusan Hrckulak, Veronika Zimolova, Felipe R. Lorenzo, Jihyun Song, Katerina Vecerkova, Olga Babosova, Linda Berkova, Vladimir Korinek, Steve Elliott, Josef T. Prchal   +10 more
wiley   +1 more source

Elderly patient with late diagnosed metastatic bone lytic lesions

Panorama of Emergency Medicine
In this case report, we present a patient with bony lytic lesions who was mobile despite having many pathological fractures and metastatic lesions. Patients should be investigated, especially in persistent pain.
Mohammed Al-Amri, Kamal Majed, Deena Kodakatill, Guru T. Arun, Mohamed M. Baumy, Adel N. Al-Hariri, Aftab Azad   +6 more
doaj   +1 more source

A Case of Obstructive Jaundice due to Bile Duct Tumor Thrombus of Hepatocellular Carcinoma Diagnosed by Peroral Cholangioscopy

DEN Open, Volume 6, Issue 1, April 2026.
Abstract While hepatocellular carcinoma (HCC) often invades the portal or hepatic vein to form tumor thrombus, tumor thrombus in the bile duct is rare. In such cases, differentiation from intrahepatic cholangiocarcinoma is difficult, and the tumor often appears as a smooth, yellowish‐white, polypoid mass within the bile duct lumen.
Keisuke Kinoshita, Mizuki Endo, Tomoko Tokumaru, Tomoko Saito, Takuro Uchida, Masao Iwao, Mie Arakawa, Kazuhisa Okamoto, Masaaki Kodama, Kazunari Murakami   +9 more
wiley   +1 more source

Pediculate hepatocarcinoma.

, 1988
PAn excep\ional case o1 pedlcula\e hepa\ocarcinomaoccurring in a previous pathological liver (massivesteatosis) is presentad.
Davidenko, Nicolás, Estapé, Gonzalo, Nuchovich, Gustavo, Lombardi, Gerardo Miguel   +3 more
openaire   +1 more source

Phyllanthus emblica Exerts Therapeutic Potential in Oral Cancer Through Multiple Pathways

eFood, Volume 7, Issue 2, April 2026.
Graphic Illustration of the Multifaceted Therapeutic Potential of PEWE, 1. Phyllanthus emblica water extract (PEWE) demonstrates potent anticancer effects against oral cancer by inhibiting cell proliferation, migration, and invasion while inducing apoptosis and autophagy. 2.
Tai‐Pei Lin, Min‐Hsiung Pan, Chan‐Hua Chang, Kuan‐Chung Hsiao, Yen‐Lin Chen, Jui‐Sheng Lai, Wen‐Chan Yang, Ann‐Joy Cheng, Yin‐Ju Chen, Chiou‐Ying Yang, Meng‐Yuan Huang, Ko‐Jiunn Liu   +11 more
wiley   +1 more source

Extracellular and Membrane Protein: Structure, Biological Functions, Diseases, and an Emerging Modality for Drug Discovery

MedComm, Volume 7, Issue 4, April 2026.
Targeted protein degradation represents a paradigm shift from traditional protein inhibition to complete protein elimination. This is achieved through three main strategies for degrading extracellular and membrane proteins: recruitment of cell‐surface LTRs, engagement of intracellular proteins, and receptor‐independent mechanisms.
Mengqing Zhao, Wenhao Yin, Jianjian Han, Huimin Wang, Zheng Liu, Lilong Liu, Wuxiang Mao   +6 more
wiley   +1 more source

Real-Life Clinical Data of Lenvatinib versus Sorafenib for Unresectable Hepatocellular Carcinoma in Italy

Cancer Management and Research, 2021
Valentina Burgio,1 Massimo Iavarone,2 Giovanni Giuseppe Di Costanzo,3 Fabio Marra,4 Sara Lonardi,5,6 Emiliano Tamburini,7 Fabio Piscaglia,8 Gianluca Masi,9,10 Ciro Celsa,11 Francesco Giuseppe Foschi,12 Marianna Silletta,13 Daniela Caterina Amoruso,14 ...
Burgio V, Iavarone M, Di Costanzo GG, Marra F, Lonardi S, Tamburini E, Piscaglia F, Masi G, Celsa C, Foschi FG, Silletta M, Amoruso DC, Rimini M, Bruccoleri M, Tortora R, Campani C, Soldà C, Viola MG, Forgione A, Conti F, Salani F, Catanese S, Giacchetto CM, Fulgenzi C, Coppola C, Lampertico P, Pellino A, Rancatore G, Cabibbo G, Ratti F, Pedica F, Della Corte A, Colombo M, De Cobelli F, Aldrighetti L, Cascinu S, Casadei-Gardini A   +36 more
doaj