Results 31 to 40 of about 25,003 (247)

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy

Case Reports in Hepatology, 2018
Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant different from hepatocarcinoma. The differences lie in genomic alterations, a greater prevalence of fibrolamellar hepatocarcinoma in young patients, and its ...
Oscar Suarez, María Perez, Martin Garzon, Rodrigo Daza, Geovanny Hernandez, Carolina Salinas, Jorge Ceballos, Enrique P. de Leon, Jacqueline Mugnier, Oscar Beltrán, Adriana Varón   +10 more
doaj   +1 more source

Effect of Allium senescens Extract on Sorafenib Resistance in Hepatocarcinoma Cells

Applied Sciences, 2021
Although Allium species are involved in bioactivity, to the best of our knowledge, there is no research on the effects of Allium senescens on drug resistance in hepatocarcinoma.
Sohyeon Park, Yoonjin Park, Heejong Shin, Boyong Kim, Seunggwan Lee   +4 more
doaj   +1 more source

MiR-122 inhibits hepatocarcinoma cell progression by targeting LMNB2.

Oncology Research, 2020
In the present study, we proposed to investigate the role of miR-122 in hepatocarcinoma progression and to explore the mechanism. In hepatocarcinoma tissues and cells, we used qRT-PCR to validate the miR-122 expression level.
Xiao-na Li, Hong Yang, Tao Yang
semanticscholar   +1 more source

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

Hepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol, Antoine Rimbert, Justina C. Wolters, Marieke Smit, Vincent W. Bloks, Niels J. Kloosterhuis, Nicolette C. A. Huijkman, Mirjam H. Koster, Umesh Tharehalli, Simon M. de Neck, Colin Bournez, Marceline M. Fuh, Jeroen Kuipers, Sujith Rajan, Alain de Bruin, Henry N. Ginsberg, Gerard J. P. van Westen, M. Mahmood Hussain, Ludger Scheja, Joerg Heeren, Philip Zimmerman, Bart van de Sluis, Jan Albert Kuivenhoven   +22 more
wiley   +1 more source

Hepatocarcinoma

, 2018
Pour la troisième année, dans le cadre du module d’enseignement « Physiopathologie de la signalisation » proposé par l’université Paris-sud, les étudiants du Master « Biologie Santé » de l’université Paris-Saclay se sont confrontés à l’écriture scientifique.
Benihoud, Karim, Dupre, Sophie, Guittet, Olivier, Le Stunff, Herve   +3 more
openaire   +2 more sources

From Non-Alcoholic Fatty Liver Disease to Liver Cancer: Microbiota and Inflammation as Key Players

Pathogens, 2023
It is estimated that 25% of the world’s population has non-alcoholic fatty liver disease. This disease can advance to a more severe form, non-alcoholic steatohepatitis (NASH), a disease with a greater probability of progression to cirrhosis and ...
Avilene Rodríguez-Lara, Ascensión Rueda-Robles, María José Sáez-Lara, Julio Plaza-Diaz, Ana I. Álvarez-Mercado   +4 more
doaj   +1 more source

Role of gut microbiota and oxidative stress in the progression of non-alcoholic fatty liver disease to hepatocarcinoma: Current and innovative therapeutic approaches

Redox Biology, 2018
Non-alcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease in industrialized countries. NAFLD progresses through the inflammatory phase of non-alcoholic steatohepatitis (NASH) to fibrosis and cirrhosis, with some cases ...
A. Borrelli, P. Bonelli, F. Tuccillo, I. Goldfine, Joseph L. Evans, F. Buonaguro, A. Mancini   +6 more
semanticscholar   +1 more source

Tratamiento del hepatocarcinoma [PDF]

Revista Clínica Española, 2004
En las ultimas dos decadas se han desarrollado formas eficaces de tratamiento del hepatocarcinoma (HCC) cuya aplicacion ha contribuido a mejorar el pronostico de una porcion relevante de los pacientes que padecen esta enfermedad (tabla 1). Sin embargo, la eleccion de la actitud terapeutica adecuada para cada caso individual sigue siendo en ocasiones ...
Sangro, B. (Bruno), Prieto, J. (Jesús)
openaire   +2 more sources

Loss of TRPV2 Homeostatic Control of Cell Proliferation Drives Tumor Progression

Cells, 2014
Herein we evaluate the involvement of the TRPV2 channel, belonging to the Transient Receptor Potential Vanilloid channel family (TRPVs), in development and progression of different tumor types.
Sonia Liberati, Maria Beatrice Morelli, Consuelo Amantini, Valerio Farfariello, Matteo Santoni, Alessandro Conti, Massimo Nabissi, Stefano Cascinu, Giorgio Santoni   +8 more
doaj   +1 more source