Results 11 to 20 of about 383,605 (247)

Hepatocellular carcinoma [PDF]

open access: yesNature Reviews Disease Primers, 2016
Liver cancer is the second leading cause of cancer-related deaths globally and has an incidence of approximately 850,000 new cases per year. Hepatocellular carcinoma (HCC) represents approximately 90% of all cases of primary liver cancer. The main risk factors for developing HCC are well known and include hepatitis B and C virus infection, alcohol ...
Llovet, Josep M.   +6 more
  +9 more sources

Hepatocellular carcinoma [PDF]

open access: yesJournal of British Surgery, 1998
Abstract Background Hepatocellular carcinoma is one of the world's most common malignancies. The aims of the present paper are to review data on (1) epidemiology and screening programmes for the early detection of the tumour and (2) advances in the diagnostic imaging and management.
Akriviadis, E. A.   +6 more
  +8 more sources

Hepatocellular carcinoma [PDF]

open access: yesBritish Journal of Cancer, 2001
The number of papers published regarding hepatocellular carcinoma between 1999 and 2001 increased from previous years. This year a study confirmed the increase in incidence in the United States. Also, several studies established for the first time that tobacco smoking was a risk factor for the development of this tumor. Several studies established that
Giovannini, M   +4 more
  +7 more sources

Hepatocellular Carcinoma [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2015
The hepatitis B virus (HBV) is a widespread human pathogen that causes liver inflammation, cirrhosis, and hepatocellular carcinoma (HCC). Recent sequencing technologies have refined our knowledge of the genomic landscape and pathogenesis of HCC, but the mechanisms by which HBV exerts its oncogenic role remain controversial.
Marie-Annick, Buendia   +1 more
openaire   +2 more sources

The Modified Response Evaluation Criteria in Solid Tumors (RECIST) Yield a More Accurate Prognoses Than the RECIST 1.1 in Hepatocellular Carcinoma Treated with Transarterial Radioembolization

open access: yesGut and Liver, 2020
Background/Aims: The Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 and modified RECIST (mRECIST) criteria have been used to assess treatment responses for hepatocellular carcinoma (HCC) patients. We investigated which criteria provides better
Jae Seung Lee   +12 more
doaj   +1 more source

Elevated N‐methyltransferase expression induced by hepatic stellate cells contributes to the metastasis of hepatocellular carcinoma via regulation of the CD44v3 isoform

open access: yesMolecular Oncology, 2019
The cross‐talk between hepatic stellate cells (HSCs) and hepatic carcinoma cells contributes to hepatocellular carcinoma (HCC) progression, but the underlying mechanism is largely unknown.
Jie Li   +17 more
doaj   +1 more source

Associated Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Registry: What Have We Learned?

open access: yesGut and Liver, 2020
In 2007, the first associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure was performed in Regensburg, Germany. ALPPS is a variation of twostage hepatectomy to induce rapid liver hypertrophy allowing the removal of ...
Hauke Lang   +2 more
doaj   +1 more source

von Willebrand Factor Antigen Predicts Outcomes in Patients after Liver Resection of Hepatocellular Carcinoma

open access: yesGut and Liver, 2020
Background/Aims: von Willebrand factor antigen (vWF-Ag) is a noninvasive predictor of portal hypertension that serves as a negative prognostic marker in various malignancies. Increased portal hypertension is associated with higher postoperative morbidity
Christoph Schwarz   +8 more
doaj   +1 more source

Clopidogrel‐induced liver damage: A case report and review of the literature

open access: yesClinical Case Reports, 2020
Liver damage is a rare side effect of clopidogrel. That is reversible in most cases. Considering the widespread use of this medication in cardiovascular diseases, the management of hepatotoxicity requires further meticulous investigation.
Vahid Eslami, Azin Gheymati
doaj   +1 more source

Epidemiological and Clinical Characteristics of Hepatitis C Virus Infection in South Korea from 2007 to 2017: A Prospective Multicenter Cohort Study

open access: yesGut and Liver, 2020
Background/Aims: This study aimed to elucidate the epidemiological and clinical characteristics of chronic hepatitis C (CHC) patients in South Korea from 2007 to 2017 and to compare the treatment patterns between two periods before and after the first ...
Joon Yeul Nam   +11 more
doaj   +1 more source

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