Results 61 to 70 of about 993,013 (333)

New human hepatocellular carcinoma (HCC) cell line with highly metastatic potential (MHCC97) and its expressions of the factors associated with metastasis

open access: yesBritish Journal of Cancer, 1999
A new human hepatocellular carcinoma (HCC) cell line with a highly metastatic potential was established from subcutaneous xenograft of a metastatic model of human HCC in nude mice (LCI-D20) by means of alternating cell culture in vitro and growth in nude
J. Tian   +6 more
semanticscholar   +1 more source

Impairments in signaling cascades mediating the progression of liver disease from chronic hepatitis to hepatocellular carcinoma in animal and human models [PDF]

open access: yes, 2011
The most common risk factors for chronic liver disease, cirrhosis, and hepatocellular carcinoma (HCC) include chronic alcohol abuse and infection with hepatitis B (HBV) or hepatitis C (HCV) virus.
Setshedi, Mashiko
core   +1 more source

Association of primary hepatocellular carcinoma laterality with oncological outcomes for hepatic resection patients: A retrospective, multicenter, propensity score-matched study

open access: yesAsian Journal of Surgery
Background & aims: The anatomical location of hepatocellular carcinoma (HCC) represents a fundamental clinical determinant of significance in the context of hepatic resection.
Okjoo Lee   +6 more
doaj   +1 more source

Combined transarterial chemoembolization and arterial administration of Bletilla striata in treatment of liver tumor in rats [PDF]

open access: yes, 2013
AIM: To evaluate and compare the effect of combined transarterial chemoembolization (TACE) and arterial administration of Bletilla striata (a Chinese traditional medicine against liver tumor) versus TACE alone for the treatment of hepatocellular ...
Vossoughi, Daryusch   +7 more
core   +1 more source

Molecular diagnosis and therapy of hepatocellular carcinoma (HCC): an emerging field for advanced technologies.

open access: yesJournal of Hepatology, 2012
Despite great progress in diagnosis and management of hepatocellular carcinoma (HCC), the exact biology of the tumor remains poorly understood overall limiting the patients' outcome.
J. Marquardt, P. Galle, A. Teufel
semanticscholar   +1 more source

HCC-Check: A Novel Diagnostic Tool for Early Detection of Hepatocellular Carcinoma Based on Cytokeratin-1 and Epithelial Membrane Antigen: A Cross-Sectional Study

open access: yesTechnology in Cancer Research & Treatment
Background: Hepatocellular carcinoma is frequently diagnosed in advanced stages, leading to a poorer prognosis. Therefore, early diagnosis and identification of biomarkers may significantly improve outcomes.
Kareem A. Attallah MSc   +4 more
doaj   +1 more source

Frequency of Elevated Hepatocellular Carcinoma (HCC) Biomarkers in Patients with Advanced Hepatitis C

open access: yesAmerican Journal of Gastroenterology, 2011
OBJECTIVES:Prospective studies of serum hepatocellular carcinoma (HCC) biomarkers in patients with advanced hepatitis C are lacking. The aim of this study was to determine the frequencies and performance of elevated α-fetoprotein (AFP), AFP-L3, and des-γ-
R. Sterling   +7 more
semanticscholar   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Detection of the level of micro RNA 224 in patients with hepatocellular carcinoma. [PDF]

open access: yesMinia Journal of Medical Research, 2019
Background: Liver cancer, predominantly hepatocellular carcinoma (HCC), is the second most deadly cancer worldwide. HCC is the most rapidly increasing cause of cancer-related mortality in the U.S.
Wael Soliman   +3 more
doaj   +1 more source

HBX suppresses PTEN to promote the malignant progression of hepatocellular carcinoma through mi-R155 activation

open access: yesAnnals of Hepatology, 2022
Introduction and objectives: Hepatocellular carcinoma (HCC) is one of the most common and fatal tumors in the world, ranking third in cancer-related mortality.
Lian-Jie Niu   +4 more
doaj   +1 more source

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