Results 71 to 80 of about 993,013 (333)

Multimodality Treatment for Early-Stage Hepatocellular Carcinoma: A Bridging Therapy for Liver Transplantation [PDF]

, 2012
Purpose: To evaluate the efficiency of a multimodality approach consisting of transcatheter arterial chemoembolization (TACE) and radiofrequency ablation (RFA) as bridging therapy for patients with hepatocellular carcinoma (HCC) awaiting orthotopic liver
Rentsch, M., P. Paprottka, F.T. Kolligs, Siegert, S., Kolligs, F. T., R.T. Hoffmann, Hoffmann, Ralf-Thorsten, Reiser, Maximilian F., Paprottka, Philipp M., D’Anastasi, Melvin, Jakobs, Tobias F., N. Ashoori, J.A. Al-Tubaikh, M.F. Reiser, Ashoori, Nima, M. Rentsch, Al-Tubaikh, J. A., Paprottka, P., Al-Tubaikh, Jarrah Ali, T.F. Jakobs, Kolligs, Frank T., Rentsch, Markus, Peporte, A., Hoffmann, R. T., M. D’Anastasi, Jakobs, T. F., D'Anastasi, M., Ashoori, N., Siegert, Sabine, S. Siegert, Bamberg, Fabian, F. Bamberg, Bamberg, F., A. Peporte   +33 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

The m6A methyltransferase METTL5 promotes neutrophil extracellular trap network release to regulate hepatocellular carcinoma progression

Cancer Medicine
Background Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide, it has a poor prognosis due to its highly invasive and metastatic nature.
Qi Wang, Yuxi Huang, Yu Zhu, Wenlong Zhang, Binfeng Wang, Xuefeng Du, Qiqiang Dai, Fabiao Zhang, Zheping Fang   +8 more
doaj   +1 more source

A case of pseudoglandular hepatocellular carcinoma: The usefulness of a multimodal approach

Radiology Case Reports, 2018
Hepatocellular carcinoma (HCC) mainly composed of the pseudoglandular pattern is very rare. We present a case of pseudoglandular HCC that was hyperechoic on ultrasound, with strongly high signal intensity on T2-weighted imaging and weak arterial contrast
Hirofumi Watanabe, MD, Yoshiki Asayama, MD, Akihiro Nishie, MD, Kousei Ishigami, MD, Yasuhiro Ushijima, MD, Daisuke Okamoto, MD, Nobuhiro Fujita, MD, Tomoharu Yoshizumi, MD, Yoshinao Oda, MD, Hiroshi Honda, MD   +9 more
doaj   +1 more source

Cross Analysis of Genomic-Pathologic Features on Multiple Primary Hepatocellular Carcinoma

Frontiers in Genetics, 2022
Hepatocellular carcinoma (HCC) is a prevalent malignancy cancer worldwide with a poor prognosis. Hepatic resection is indicated as a potentially curative option for HCC patients in the early stage.
Fei Ren, Depin Wang, Xueyuan Zhang, Xueyuan Zhang, Na Zhao, Xiaowen Wang, Yu Zhang, Li Li   +7 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

AN INITIAL INDICATION OF PREDISPOSING RISK OF SCHISTOSOMA MANSONI INFECTION FOR HEPATOCELLULAR CARCINOMA [PDF]

Journal of the Egyptian Society of Parasitology, 2015
Estimated 500,000 - 1 million cases of hepatocellular carcinoma (HCC) are reported to occur yearly worldwide, with a mean annual incidence of around 3 – 4% of global population.
INAS ABDEL AZIZ, YOSSRA NABIL, NAGLAA MAHMOUD, AMANY ABD EL-AAL, ABD EL HAMID SABRY   +4 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Identification of ferroptosis-related genes for overall survival prediction in hepatocellular carcinoma

Scientific Reports, 2022
Ferroptosis is a novel type of cell death depending on iron and is strongly related to the development of tumors. Hepatocellular carcinoma (HCC) is a malignancy with high incidence.
Lianxiang Luo, Xinyue Yao, Jing Xiang, Fangfang Huang, Hui Luo   +4 more
doaj   +1 more source

Precision diagnosis of hepatocellular carcinoma

Chinese Medical Journal, 2023
. Hepatocellular carcinoma (HCC) is the most common type of primary hepatocellular carcinoma (PHC). Early diagnosis of HCC remains the key to improve the prognosis.
Zhenxiao Wang, Hanjiao Qin, Shui Liu, Jiyao Sheng, Xuewen Zhang, Yanjie Yin   +5 more
doaj   +1 more source