Results 41 to 50 of about 140,561 (343)

Prognostic value of interleukin-10 and tumor necrosis factor-α polymorphisms in patients with hepatocellular carcinoma treated with transarterial chemoembolization

open access: yesThe Egyptian Journal of Internal Medicine, 2019
Background Transarterial chemoembolization (TACE), a locoregional therapy, is widely recommended as first-line treatment for intermediate-stage hepatocellular carcinoma (HCC).
Ahmed A Ghafar   +4 more
doaj   +1 more source

First human study in treatment of unresectable liver metastases from colorectal cancer with irinotecan-loaded beads (DEBIRI) [PDF]

open access: yes, 2012
The objective of this pilot clinical study was to assess the safety, technical feasibility, pharmacokinetic (PK) profile and tumour response of DC Bead™ with irinotecan (DEBIRI™) delivered by intra-arterial embolisation for the treatment of metastatic ...
Eichler, Katrin   +6 more
core   +1 more source

Obesity as a cause of hepatocellular carcinoma

open access: yesAnnals of Hepatology, 2015
During recent years the incidence of obesity has increased significantly, and in some instances rapidly, in many resource-rich countries. Paralleling this increase has been an increase in the incidence of hepatocellular carcinoma.
Michael C. Kew
doaj   +1 more source

Polyethylene Glycol Epirubicin-Loaded Transcatheter Arterial Chemoembolization Procedures Utilizing a Combined Approach with 100 and 200 μm Microspheres: A Promising Alternative to Current Standards [PDF]

open access: yes, 2019
PURPOSE:To report clinical effectiveness, toxicity profile, and prognostic factors of combined 100 μm ± 25 and 200 μm ± 50 epirubicin-loaded polyethylene glycol (PEG) microsphere drug-eluting embolic transcatheter arterial chemoembolization protocol in ...
Argirò, Renato   +12 more
core   +1 more source

Clinical Relevance of Transjugular Liver Biopsy in Comparison with Percutaneous and Laparoscopic Liver Biopsy

open access: yesGastroenterology Research and Practice, 2009
Background. Transjugular liver biopsy (TJLB) is frequently used to obtain liver specimens in high-risk patients. However, TJLB sample size possibly limits their clinical relevance. Methods. 102 patients that underwent TJLB were included.
Max G. Beckmann   +9 more
doaj   +1 more source

T2 Hepatocellular Carcinoma Exception Policies That Prolong Waiting Time Improve the Use of Evidence-based Treatment Practices

open access: yesTransplantation Direct, 2020
Background. A United Network for Organ Sharing policy change in 2015 created a 6-mo delay in the receipt of T2 hepatocellular carcinoma exception points.
Claire Durkin, MD   +2 more
doaj   +1 more source

Tubeimoside-2 Triggers Methuosis in Hepatocarcinoma Cells through the MKK4–p38α Axis

open access: yesPharmaceutics, 2023
Liver cancer, consisting mainly of hepatocellular carcinoma, is the third leading cause of cancer-related mortality worldwide. Despite advances in targeted therapies, these approaches remain insufficient in meeting the pressing clinical demands. Here, we
Yichao Gan   +9 more
doaj   +1 more source

Midzonal Necrosis as a Pattern of Hepatocellular Injury After Shock

open access: yesGastroenterology, 1984
Midzonal necrosis is rarely observed in human liver, except in patients with yellow fever. In a retrospective analysis of livers from 1000 consecutively autopsied adult patients, we observed midzonal necrosis in 1.8% of the cases, and in 8% of patients with centrilobular necrosis.
S M, de la Monte   +3 more
openaire   +2 more sources

Expression of a Secretory Protein C1qTNF6, a C1qTNF Family Member, in Hepatocellular Carcinoma

open access: yesAnalytical Cellular Pathology, 2011
Background: Recent studies have revealed that the adiponectin-associated protein belonging to the C1qTNF family mediates various biological processes. However, the pathobiological property of C1qTNF6 in carcinogenesis remains unclear.
Tamotsu Takeuchi   +2 more
doaj   +1 more source

Au-24 as a potential thioredoxin reductase inhibitor in hepatocellular carcinoma cells

open access: yesPharmacological Research, 2022
A novel TrxR inhibitor Au-24 and its inhibitory ability to hepatocellular carcinoma in vitro and in vivo is reported herein. Au-24 can suppress HepG2 cells from proliferating by lowering mitochondrial membrane potential (MMP) and increasing reactive ...
Gaopan Dong   +7 more
doaj   +1 more source

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