Results 71 to 80 of about 140,561 (343)

Role of transarterial chemoembolization as neoadjuvant treatment in T2 stage patients waiting for liver transplantation [PDF]

, 2012
RIASSUNTO Scopo: Valutare retrospettivamente i risultati clinici a lungo termine di pazienti cirrotici con HCC allo stadio T2 sottoposti a trapianto ortotopico di fegato (TOF) dopo chemioembolizzazione intraarteriosa (TACE), rispetto ai risultati ...
BARATTINI, MATTEO
core  

Sarcoidosis-associated hepatocellular carcinoma [PDF]

, 2010
Sarcoidosis is a systemic granulomatous inflammation of unknown etiology, and seems to involve the liver parenchyma in most cases. However, sarcoidosis-associated hepatocellular carcinoma is rare. We report here a case in which a hepatocellular carcinoma
Aiko, Satoshi, Horio, Takuya, Kawai, Toshiaki, Nakanishi, Kuniaki, Ogata, Sho, Saito, Hiroki, Shimazaki, Hideyuki, Sugiura, Yoshiaki   +7 more
core   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

Preclinical Study of Locoregional Therapy of Hepatocellular Carcinoma by Bioelectric Ablation with Microsecond Pulsed Electric Fields (μsPEFs)

Scientific Reports, 2015
Unresectable hepatocellular carcinoma (HCC) needs locoregional ablation as a curative or downstage therapy. Microsecond Pulsed Electric Fields (μsPEFs) is an option.
Xinhua Chen, Zhigang Ren, Chengxiang Li, Fei Guo, Dianbo Zhou, Jianwen Jiang, Xinmei Chen, Jihong Sun, Chenguo Yao, Shusen Zheng   +9 more
doaj   +1 more source

Tumor necrosis as a predictor of early tumor recurrence after resection in patients with hepatoma.

PLoS ONE, 2023
BackgroundTumor necrosis is a significant risk factor affecting patients' prognosis after liver resection (LR) for hepatocellular carcinoma (HCC). We aimed to develop a model with tumor necrosis as a variable to predict early tumor recurrence in HCC ...
Yi-Hao Yen, Fang-Ying Kuo, Hock-Liew Eng, Yueh-Wei Liu, Chee-Chien Yong, Wei-Feng Li, Chih-Chi Wang, Chih-Yun Lin   +7 more
doaj   +1 more source

Hepatic microRNA profiles offer predictive and mechanistic insights after exposure to genotoxic and epigenetic hepatocarcinogens. [PDF]

, 2012
In recent years, accumulating evidence supports the importance of microRNAs in liver physiology and disease; however, few studies have examined the involvement of these noncoding genes in chemical hepatocarcinogenesis.
Currie, RA, Gooderham, NJ, Koufaris, C, Wright, J   +3 more
core   +1 more source

Locoregional Therapies for Hepatocellular Carcinoma prior to Liver Transplant: Comparative Pathologic Necrosis, Radiologic Response, and Recurrence [PDF]

, 2023
McKenzie Mosenthal, William Adams, Scott J. Cotler, Xianzhong Ding, Marc A. Borge, A. Malamis, David D. Lee, Tarita O. Thomas, A. Jawahar, Parag Amin, Christopher Molvar   +10 more
openalex   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Low alanine aminotransferase activity gene variant in a Siberian Husky with copper-associated hepatopathy

BMC Veterinary Research, 2023
Background Alanine aminotransferase (ALT) is commonly used as a marker of hepatocellular injury. Increased serum ALT activity due to hepatocyte injury occurs in copper-associated hepatopathy (CuCH) and other necroinflammatory liver conditions.
Christine Kim, John P. Loftus, Heather J. Huson   +2 more
doaj   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source