Results 1 to 10 of about 200,853 (296)

Dynamic soluble changes in sVEGFR1, HGF, and VEGF promote chemotherapy and bevacizumab resistance: A prospective translational study in the BECOX (GEMCAD 09-01) trial [PDF]

Tumor Biology, 2017
Despite initial responsiveness, acquired resistance to both bevacizumab and chemotherapy in metastatic colorectal cancer is universal. We have recently published that in vitro, chronically oxaliplatin resistance upregulates soluble vascular endothelial ...
Estela Pineda, A Salud, E Vila-Navarro, MJ Safont, Beatriz Llorente, J Aparicio, R Vera, P Escudero, E Casado, C Bosch, U Bohn, R Pérez-Carrión, A Carmona, JR Ayuso, T Ripollés, R Bouzas, M Gironella, X García-Albéniz, J Feliu, J Maurel   +19 more
doaj   +3 more sources

Hepatocyte Growth Factor and Cardiac Amyloidosis∗

JACC. CardioOncology, 2020
[Figure: see text]
Frederick L. Ruberg, MD, Omar K. Siddiqi, MD   +1 more
doaj   +3 more sources

Hepatocyte Growth Factor Differentially Modulates Oral Microbiota in Early vs. Late Experimental Periodontitis [PDF]

Biology
Background: Periodontitis is a chronic disease triggered by disturbed oral microbiota. We have previously reported that hepatocyte growth factor (HGF) could mitigate early-stage experimental periodontitis but exacerbate the condition in its late stage ...
Ruotong Ji, Xiaomin Zhao, Zhen Chen, Yifei Ge, Zhicong Wu, Xinhong Wang   +5 more
doaj   +2 more sources

Function of hepatocyte spheroids in bioactive microcapsules is enhanced by endogenous and exogenous hepatocyte growth factor [PDF]

Bioactive Materials, 2023
The ability to maintain functional hepatocytes has important implications for bioartificial liver development, cell-based therapies, drug screening, and tissue engineering. Several approaches can be used to restore hepatocyte function in vitro, including
Kihak Gwon, Daheui Choi, José M. de Hoyos-Vega, Harihara Baskaran, Alan M. Gonzalez-Suarez, Seonhwa Lee, Hye Jin Hong, Kianna M. Nguyen, Ether Dharmesh, Go Sugahara, Yuji Ishida, Takeshi Saito, Gulnaz Stybayeva, Alexander Revzin   +13 more
doaj   +2 more sources

Hepatocyte Growth Factor: A Marker of Cardiac Function, Mortality, and Disease Subtype in Cardiac Amyloidosis. [PDF]

JACC Adv
Holt MF, Michelsen AE, Flø A, Khan Y, Bjørnø VK, Skjelland M, Bjerkeli V, Paus B, Kvitting JP, Halvorsen B, Wien TN, Raki M, Gullestad L, Aukrust P, Broch K, Ueland T, Gude E.   +16 more
europepmc   +2 more sources

Interferon-β induces hepatocyte growth factor in monocytes of multiple sclerosis patients. [PDF]

PLoS ONE, 2012
Interferon-β is a first-line therapy used to prevent relapses in relapsing-remitting multiple sclerosis. The clinical benefit of interferon-β in relapsing-remitting multiple sclerosis is attributed to its immunomodulatory effects on inflammatory ...
Nicolas Molnarfi, Mahdia Benkhoucha, Kristbjörg Bjarnadóttir, Catherine Juillard, Patrice H Lalive   +4 more
doaj   +1 more source

A single injection of CM1021, a long half-life hepatocyte growth factor mimetic, increases liver mass in mice

Biochemistry and Biophysics Reports, 2021
Despite years of positive animal data, hepatocyte growth factor (HGF) has never been developed into a useful pharmaceutical, primarily due to its poor pharmacological properties. CM1021 is a fusion protein containing the K1 loop of HGF and the human IgG1
James H. Kelly
doaj   +1 more source

Hepatocyte growth factor pathway expression in breast cancer by race and subtype

Breast Cancer Research, 2021
Background African American women have the highest risk of breast cancer mortality compared to other racial groups. Differences in tumor characteristics have been implicated as a possible cause; however, the tumor microenvironment may also contribute to ...
Gieira S. Jones, Katherine A. Hoadley, Linnea T. Olsson, Alina M. Hamilton, Arjun Bhattacharya, Erin L. Kirk, Heather J. Tipaldos, Jodie M. Fleming, Michael I. Love, Hazel B. Nichols, Andrew F. Olshan, Melissa A. Troester   +11 more
doaj   +1 more source

The relationship between clinical parameters and hepatocyte growth factor/c-Met levels in the sperm of infertile males

Journal of Men's Health, 2022
Objective: Hepatocyte growth factor is a pleiotropic cytokine with potent mitogenic activity in many organs and tissues. The receptor for hepatocyte growth factor is c-Met, a transmembrane glycoprotein with tyrosine kinase activity.
Basak Ozge Kayan, Veysel Sabri Hancer, Uzay Gormus, Cenk Ozcan, Faruk Abike, Cem Murat Baykal   +5 more
doaj   +1 more source

Hepatocyte growth factor

Hepatology, 1992
The two papers in this issue of Hepatology (1, 2) dealing with hepatocyte growth factor (HGF) underscore the increasing importance of this novel growth factor in relation to hepatic growth biology. The emerging literature has already established HGF as a growth factor with potential importance not only for the liver but for ...
G K, Michalopoulos, R, Zarnegav
openaire   +4 more sources