Results 161 to 170 of about 58,347 (252)

Immunomodulatory interactions between mesenchymal stromal/stem cells and immune cells in psoriasis: therapeutic potential and challenges. [PDF]

Stem Cell Res Ther
Dashti M, Mohammadi M, Dehnavi S, Sadeghi M.   +3 more
europepmc   +1 more source

Understanding erythroid physiology and pathology in humanized mice: A closer look

British Journal of Haematology, Volume 206, Issue 5, Page 1272-1284, May 2025.
Erythropoiesis, the formation of red blood cells (RBCs) from haematopoietic stem cells (HSCs), is vital for understanding conditions like anaemia and haemoglobinopathies. However, studying this process in vivo is challenging due to the lack of accurate models.
Lu Lu, Chenfei Liu, Lezong Chen, Xumiao Zhang, Yinglin Su, Zhenzhen Chou, Yang Liang, Yuanbin Song   +7 more
wiley   +1 more source

Bioengineered extracellular vesicles: The path to precision medicine in liver diseases. [PDF]

Liver Res
Mittal A, Jakhmola VR, Baweja S.
europepmc   +1 more source

Innovative pharmacotherapy for hepatic metabolic and chronic inflammatory diseases in China

British Journal of Pharmacology, EarlyView.
Abstract Liver disease constitutes a significant global health concern, particularly in China where it has distinctive characteristics. China grapples with a staggering 300 million cases, predominantly due to hepatitis B and metabolic non‐alcoholic fatty liver disease. Additionally, hepatocellular carcinoma has become a prevalent which is a lethal type
Feng Zhang, Jiaming Ju, Hongtao Diao, Jinglun Song, Yu bian, Baofeng Yang   +5 more
wiley   +1 more source

Characterization and Proteomic Profiling of Hepatocyte-like Cells Derived from Human Wharton's Jelly Mesenchymal Stromal Cells: De Novo Expression of Liver-Specific Enzymes. [PDF]

Biology (Basel)
Lo Iacono M, Corrao S, Alberti G, Amico G, Timoneri F, Russo E, Cucina A, Indelicato S, Rappa F, Corsello T, Saieva S, Di Stefano A, Di Gaudio F, Conaldi PG, La Rocca G.   +14 more
europepmc   +1 more source

G protein‐coupled receptor‐mediated autophagy in health and disease

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan, Zeynep Aslıhan Durer, Beki Kan   +2 more
wiley   +1 more source

Preventive and Therapeutic Effects of Baicalein, Galangin, and Isorhamnetin in Chronic Liver Diseases: A Narrative Review. [PDF]

Molecules
Scarlata GGM, Lopez I, Gambardella ML, Milanović M, Milić N, Abenavoli L.   +5 more
europepmc   +1 more source

Scutellarin Alleviates Bone Marrow Mesenchymal Stromal Cellular Senescence via the Ezh2‐Nrf2 Signalling Axis in Diabetes‐Induced Bone Loss

Cell Proliferation, Volume 58, Issue 4, April 2025.
The Ezh2‐Nrf2 signalling axis plays a crucial role in mediating the beneficial effects of SCU under DOP conditions. ABSTRACT Currently, there is no specific treatment for diabetes‐induced osteoporosis (DOP). Our study identified diabetes‐induced cellular senescence, marked by elevated activity of senescence‐associated β‐galactosidase.
Tiantian Wang, Jiehao Chen, Bo Qu, Dong Zhou, Zhen Hong   +4 more
wiley   +1 more source

Suppression of regulatory factor X 7 alleviates airway remodeling and inflammation in childhood asthma.

Cytojournal
Wu Y, Dai T, Qin J, Guo J, Fan J, Mei J, Li X, Liu F.   +7 more
europepmc   +1 more source

The Active Components of Traditional Chinese Medicines Regulate the Multi-Target Signaling Pathways of Metabolic Dysfunction-Associated Fatty Liver Disease. [PDF]

Drug Des Devel Ther
Song Z, Bu S, Sang S, Li J, Zhang X, Song X, Ran Y.   +6 more
europepmc   +1 more source