Results 131 to 140 of about 628,453 (389)

Self‐Feeding of Engineered Tissues via Controlled Glucose Release Facilitates Survival and Vascularization of Living Implants

open access: yesAdvanced Functional Materials, EarlyView.
ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian   +5 more
wiley   +1 more source

Effects of Simultaneous Downregulation of PHD1 and Keap1 on Prevention and Reversal of Liver Fibrosis in Mice

open access: yesFrontiers in Pharmacology, 2018
Background and Aim: To investigate whether double-knockdown of PHD1 and Keap1 in mice could enhance the resolution of carbon tetrachloride (CCl4)-induced liver fibrosis.Methods: The liver fibrosis model of mice was established by intraperitoneal ...
Jing Liu   +7 more
doaj   +1 more source

Hepatocyte transplantation [PDF]

open access: yesTransplant International, 1996
Michio Mito, Masayuki Sawa
openaire   +1 more source

Fibroblasts Derive from Hepatocytes in Liver Fibrosis via Epithelial to Mesenchymal Transition*

open access: yesJournal of Biological Chemistry, 2007
Activated fibroblasts are key contributors to the fibrotic extracellular matrix accumulation during liver fibrosis. The origin of such fibroblasts is still debated, although several studies point to stellate cells as the principal source.
M. Zeisberg   +6 more
semanticscholar   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee   +9 more
wiley   +1 more source

Antioxidant effect of the essential oil and extract of Matricaria chamomilla L. on isolated rat hepatocytes

open access: yesJournal of Medicinal Plants, 2002
Free radicals are active molecules that are present every where and may be of internal or external origin. One of the most important destructive effects of free radicals is promoting lipid peroxidation resulting membrane destruction.
Sedigheh Asgary   +3 more
doaj  

Exploring Metabolic Consequences of CPS1 and CAD Dysregulation in Hepatocellular Carcinoma by Network Reconstruction

open access: yesJournal of Hepatocellular Carcinoma, 2020
Ozbil E Dumenci, Abellona MR U, Shahid A Khan, Elaine Holmes, Simon D Taylor-Robinson Imperial College London, London, UKCorrespondence: Abellona MR UImperial College London, 660 Sir Alexander Fleming Building, London SW7 2AZ, UKTel +44 7428 274231Email ...
Dumenci OE   +4 more
doaj  

Enhanced Transgene Expression from Recombinant Single-Stranded D-Sequence-Substituted Adeno-Associated Virus Vectors in Human Cell Lines In Vitro and in Murine Hepatocytes In Vivo [PDF]

open access: bronze, 2014
Chen Ling   +14 more
openalex   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

open access: yesAdvanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao   +20 more
wiley   +1 more source

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