Results 131 to 140 of about 628,453 (389)
ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian +5 more
wiley +1 more source
Background and Aim: To investigate whether double-knockdown of PHD1 and Keap1 in mice could enhance the resolution of carbon tetrachloride (CCl4)-induced liver fibrosis.Methods: The liver fibrosis model of mice was established by intraperitoneal ...
Jing Liu +7 more
doaj +1 more source
Hepatocyte transplantation [PDF]
Michio Mito, Masayuki Sawa
openaire +1 more source
Fibroblasts Derive from Hepatocytes in Liver Fibrosis via Epithelial to Mesenchymal Transition*
Activated fibroblasts are key contributors to the fibrotic extracellular matrix accumulation during liver fibrosis. The origin of such fibroblasts is still debated, although several studies point to stellate cells as the principal source.
M. Zeisberg +6 more
semanticscholar +1 more source
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee +9 more
wiley +1 more source
Free radicals are active molecules that are present every where and may be of internal or external origin. One of the most important destructive effects of free radicals is promoting lipid peroxidation resulting membrane destruction.
Sedigheh Asgary +3 more
doaj
Ozbil E Dumenci, Abellona MR U, Shahid A Khan, Elaine Holmes, Simon D Taylor-Robinson Imperial College London, London, UKCorrespondence: Abellona MR UImperial College London, 660 Sir Alexander Fleming Building, London SW7 2AZ, UKTel +44 7428 274231Email ...
Dumenci OE +4 more
doaj
Enhanced Transgene Expression from Recombinant Single-Stranded D-Sequence-Substituted Adeno-Associated Virus Vectors in Human Cell Lines In Vitro and in Murine Hepatocytes In Vivo [PDF]
Chen Ling +14 more
openalex +1 more source
Propofol Pretreatment Inhibits Liver Damage in Mice with Hepatic Ischemia/Reperfusion Injury and Protects Human Hepatocyte in Hypoxia/Reoxygenation [PDF]
Jing Li +5 more
openalex +1 more source
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao +20 more
wiley +1 more source

