Results 121 to 130 of about 137,616 (341)

Rapid bupropion-induced hepatotoxicity: a case report and review of the literature

open access: yesJournal of Medical Case Reports, 2018
Background Bupropion is an antidepressant that is also used as a non-nicotine method to aid in smoking cessation. Bupropion-induced hepatotoxicity is quoted to affect between 0.1% and 1% of treated patients with either a hepatocellular and/or cholestatic
Sulakchanan Anandabaskaran, Vincent Ho
doaj   +1 more source

Intelligent Theranostic Systems Enabled by Aggregation‐Induced Emission in Precision Medicine

open access: yesAggregate, EarlyView.
Aggregation‐induced emission (AIE) luminogens are driving a new generation of intelligent theranostic systems that integrate high‐fidelity imaging and multifunctional therapy. This review highlights how AIEgens, through restriction of intramolecular motion (RIM), enable deep‐tissue NIR‐II imaging, ultrasensitive biosensing, CRISPR‐assisted gene ...
Qinqin Huang   +7 more
wiley   +1 more source

Fimbriae‐Targeted Peptide‐Selenoviologen Cyclophane Complex for Enhanced Photodynamic Therapy of Periodontitis

open access: yesAggregate, EarlyView.
This study develops a supramolecular photosensitizer (SeVB⊃PQ) by combining SeVB with a P. gingivalis‐targeting peptide. SeVB⊃PQ selectively binds P. gingivalis, boosts ROS generation under irradiation, disrupts ATP synthesis, restores microbial balance, reduces inflammation, and promotes alveolar bone regeneration, offering a promising platform for ...
Rui Ding   +7 more
wiley   +1 more source

Vitamin E and hepatotoxic agents [PDF]

open access: bronze, 1969
J. Green   +3 more
openalex   +1 more source

Advances in miRNA research: Unraveling the complexities of gene regulation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Overview of miRNA‐mediated regulation in key biological processes. This illustration offers a comprehensive view of the diverse functions that microRNAs perform in governing various biological processes, highlighting their profound significance within the complex web of gene expression and cellular function.
Jiawei Zheng, Guoqing Zhang, Linzhu Ren
wiley   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić   +4 more
wiley   +1 more source

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