Results 121 to 130 of about 146,077 (348)

Outcomes and safety of concomitant nevirapine and rifampicin treatment under programme conditions in Malawi. [PDF]

open access: yes, 2010
SETTING: Thyolo District Hospital, rural Malawi. OBJECTIVES: To report on 1) clinical, immunological and virological outcomes and 2) safety among human immunodeficiency virus (HIV) infected patients with tuberculosis (TB) who received concurrent ...
Bauerfeind, A   +9 more
core   +1 more source

The low intestinal and hepatic toxicity of hydrolyzed fumonisin B1 correlates with its inability to alter the metabolism of sphingolipids [PDF]

open access: yes, 2012
Fumonisins are mycotoxins frequently found as natural contaminants in maize, where they are produced by the plant pathogen Fusarium verticillioides. They are toxic to animals and exert their effects through mechanisms involving disruption of sphingolipid
Bracarense, Ana-Paula   +8 more
core   +1 more source

Isolation and Extraction of Gentian Polysaccharide and Its Protective Effect on Chemical Liver Injury

open access: yesFood Safety and Health, EarlyView.
The water‐soluble polysaccharide GSBP‐N‐a‐1 with an average molecular weight of 3.82 kDa was successfully isolated and purified from Gentiana scabra. It was confirmed that the crude polysaccharides of Gentiana scabra could inhibit oxidative stress and inflammatory response by activating the Nrf2‐HO‐1 pathway, and significantly alleviate the chemical ...
Tianjiao Fu, Yan Dong, Guangxin Yuan
wiley   +1 more source

Acute and subacute hepatotoxicity of genipin in mice and its potential mechanism

open access: yesHeliyon, 2023
Gardenia, as a medicinal and edible herb, has the pharmacological activity of protecting the liver and cholagogue, but the hepatotoxicity induced by the chemical component genipin (GP) limits its application.
Shuaikang Wang   +8 more
doaj  

Phytochemical Contents and Bioactive Compounds in Widely Consumed Cereals, Legumes, and Vegetables in Abruzzo Region, Italy: A Critical Review

open access: yesFood Safety and Health, EarlyView.
This review aims to collect and identify cereals, legumes, and vegetables mostly consumed in the Abruzzo region from 2020 till now, pointing attention to their biological effects. ABSTRACT The Abruzzo region boasts a wide range of typical food products including cereals, legumes, and vegetables. In this context, they take part in the Mediterranean diet,
Giulia Gentile   +3 more
wiley   +1 more source

Identification of a metabolic biomarker panel in rats for prediction of acute and idiosyncratic hepatotoxicity

open access: yesComputational and Structural Biotechnology Journal, 2014
It has been estimated that 10% of acute liver failure is due to “idiosyncratic hepatotoxicity”. The inability to identify such compounds with classical preclinical markers of hepatotoxicity has driven the need to discover a mechanism-based biomarker ...
Jinchun Sun   +8 more
doaj   +1 more source

Vitamin E and hepatotoxic agents [PDF]

open access: bronze, 1969
J. Green   +3 more
openalex   +1 more source

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