Results 221 to 230 of about 160,647 (335)

The Proteomic Profiling of Circulating Extracellular Vesicles of Western Diet and Chemical‐Induced Murine MASH Model

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is an increasingly prevalent chronic liver condition that can progress to severe complications such as metabolic dysfunction‐associated steatohepatitis (MASH). Despite its growing burden, there are no reliable non‐invasive biomarkers for tracking disease progression.
Szu‐Jen Wang   +9 more
wiley   +1 more source

MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen   +4 more
wiley   +1 more source

The use of cyclosporine in organ transplants [PDF]

open access: yes, 1984
Gordon, RD   +3 more
core  

Nanoformulated Diacerein Alleviates Hyperlipidemia via Gut Microbiota Modulation In Vivo

open access: yesNano Select, EarlyView.
A nanoformulation of diacerein (Nano‐DIA) was fabricated with carboxymethyl cellulose, achieving enhanced solubility and rapid dissolution for alternative anti‐hyperlipidemia therapeutics. Mechanistic studies revealed its in vivo lipid‐lowering efficacy is through metabolite‐mediated and microbiota‐dependent manner, highlighting its dual action on host
Zheng Peng   +8 more
wiley   +1 more source

Liver Transplantation in PNPO Deficiency: Management Challenges and Biological Lessons. [PDF]

open access: yesJIMD Rep
Webster R   +12 more
europepmc   +1 more source

Hepatoprotective effect of vitamin A and E on diclofenac induced hepatotoxicity in male Wistar albino rats

open access: diamond, 2019
T Siva   +6 more
openalex   +1 more source

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

open access: yesChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges   +15 more
wiley   +1 more source

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